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Development and validation of cancer-associated fibroblasts-related gene landscape in prognosis and immune microenvironment of bladder cancer.
Zhang M, Zhu J, Zhang P, Li L, Min M, Li T, He W. Zhang M, et al. Front Oncol. 2023 Jun 15;13:1174252. doi: 10.3389/fonc.2023.1174252. eCollection 2023. Front Oncol. 2023. PMID: 37397364 Free PMC article.
BACKGROUNDS: Bladder cancer (BLCA) is one of the most prevalent cancers of the genitourinary system, the clinical outcomes of patients with BLCA are bad, and the morbidity rate is high. ...Previous studies have shown the involvement of CAFs in tumor growth, cance …
BACKGROUNDS: Bladder cancer (BLCA) is one of the most prevalent cancers of the genitourinary system, the clinical outcomes of …
A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma.
Das Mahapatra K, Pasquali L, Søndergaard JN, Lapins J, Nemeth IB, Baltás E, Kemény L, Homey B, Moldovan LI, Kjems J, Kutter C, Sonkoly E, Kristensen LS, Pivarcsi A. Das Mahapatra K, et al. Sci Rep. 2020 Feb 27;10(1):3637. doi: 10.1038/s41598-020-59660-6. Sci Rep. 2020. PMID: 32108138 Free PMC article.
Cutaneous Squamous Cell Carcinoma (cSCC) is the most common and fastest-increasing cancer with metastatic potential. Long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) are novel regulators of gene expression. ...Representative transcripts were validated by NanoStr …
Cutaneous Squamous Cell Carcinoma (cSCC) is the most common and fastest-increasing cancer with metastatic potential. Long non-coding …
Identification of candidate genes and long non-coding RNAs associated with the effect of ATP5J in colorectal cancer.
Bai B, Xie B, Pan Z, Shan L, Zhao J, Zhu H. Bai B, et al. Int J Oncol. 2018 Apr;52(4):1129-1138. doi: 10.3892/ijo.2018.4281. Epub 2018 Feb 22. Int J Oncol. 2018. PMID: 29484395 Free PMC article.
The incidence and development of colorectal cancer (CRC) is a process with multiple gene interactions. We have previously demonstrated that ATP synthase-coupling factor 6, mitochondrial (ATP5J) is associated with CRC migration and 5-fluorouracil resistance; nevertheless, t …
The incidence and development of colorectal cancer (CRC) is a process with multiple gene interactions. We have previously demonstrate …
Immunohistochemistry in the Diagnosis of Mucinous Neoplasms Involving the Ovary: The Added Value of SATB2 and Biomarker Discovery Through Protein Expression Database Mining.
Strickland S, Wasserman JK, Giassi A, Djordjevic B, Parra-Herran C. Strickland S, et al. Int J Gynecol Pathol. 2016 May;35(3):191-208. doi: 10.1097/PGP.0000000000000238. Int J Gynecol Pathol. 2016. PMID: 26535987
Conversely, SATB2 was more specific for lower GI origin, being positive in 78.8% lower GI but only 11.5% upper GI and 1.7% primary ovarian neoplasms. PAX8 expression was common in primary ovarian neoplasms (75% of all neoplasms, 65% of carcinomas); only 1 (1. …
Conversely, SATB2 was more specific for lower GI origin, being positive in 78.8% lower GI but only 11.5% upper GI and 1.7% primary ovarian …
Meiotic genes in premature ovarian insufficiency: variants in HROB and REC8 as likely genetic causes.
Tucker EJ, Bell KM, Robevska G, van den Bergen J, Ayers KL, Listyasari N, Faradz SM, Dulon J, Bakhshalizadeh S, Sreenivasan R, Nouyou B, Carre W, Akloul L, Duros S, Domin-Bernhard M, Belaud-Rotureau MA, Touraine P, Jaillard S, Sinclair AH. Tucker EJ, et al. Eur J Hum Genet. 2022 Feb;30(2):219-228. doi: 10.1038/s41431-021-00977-9. Epub 2021 Oct 28. Eur J Hum Genet. 2022. PMID: 34707299 Free PMC article.
In addition to infertility, patients face increased risk of comorbidities such as heart disease, osteoporosis, cancer and/or early mortality. We used whole exome sequencing to identify the genetic cause of POI in seven women. ...We also identified novel variants in MCM8, N …
In addition to infertility, patients face increased risk of comorbidities such as heart disease, osteoporosis, cancer and/or early mo …
Construction and Analysis of a circRNA-Mediated ceRNA Network in Lung Adenocarcinoma.
Wang Z, Pei H, Liang H, Zhang Q, Wei L, Shi D, Chen Y, Zhang J. Wang Z, et al. Onco Targets Ther. 2021 Jun 8;14:3659-3669. doi: 10.2147/OTT.S305030. eCollection 2021. Onco Targets Ther. 2021. PMID: 34135596 Free PMC article.
BACKGROUND: Circular RNAs (circRNAs), a new class of regulatory noncoding RNAs, are involved in gene regulation and may play a role in cancer development. The aim of this study was to identify circRNAs involved in lung adenocarcinoma (LUAD) using bioinformatics analysis. . …
BACKGROUND: Circular RNAs (circRNAs), a new class of regulatory noncoding RNAs, are involved in gene regulation and may play a role in ca …
The transcriptional regulator CBX2 and ovarian function: A whole genome and whole transcriptome approach.
Bouazzi L, Sproll P, Eid W, Biason-Lauber A. Bouazzi L, et al. Sci Rep. 2019 Nov 19;9(1):17033. doi: 10.1038/s41598-019-53370-4. Sci Rep. 2019. PMID: 31745224 Free PMC article.
We identified CBX2 regulated genes associated with polycystic ovary syndrome (PCOS) such as TGFbeta, MAP3K15 and DKK1, as well as genes implicated in premature ovarian failure (POF) (i.e. POF1B, BMP15 and HOXA13) and the pituitary deficiency (i.e. LHX4 and KISS1). ...
We identified CBX2 regulated genes associated with polycystic ovary syndrome (PCOS) such as TGFbeta, MAP3K15 and DKK1, as well as genes impl …
A clinical proteomics study of exhaled breath condensate and biomarkers for pulmonary embolism.
Gade IL, Riddersholm SJ, Stilling-Vinther T, Brøndum RF, Bennike TB, Honoré B. Gade IL, et al. J Breath Res. 2023 Nov 17;18(1). doi: 10.1088/1752-7163/ad0aaa. J Breath Res. 2023. PMID: 37939397
The levels of HSPA5, PEBP1 and SFTPA2 were higher and levels of POF1B, EPPK1, PSMA4, ALDOA, and CFL1 were lower in PE compared with controls. ...
The levels of HSPA5, PEBP1 and SFTPA2 were higher and levels of POF1B, EPPK1, PSMA4, ALDOA, and CFL1 were lower in PE compared with c …