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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 4
1949 1
1950 5
1951 2
1953 2
1954 1
1955 2
1956 3
1957 1
1958 1
1960 1
1961 1
1962 2
1963 1
1964 4
1965 1
1966 1
1967 5
1968 5
1970 4
1971 1
1972 2
1973 5
1974 4
1975 19
1976 20
1977 13
1978 14
1979 20
1980 18
1981 15
1982 13
1983 17
1984 24
1985 24
1986 29
1987 22
1988 26
1989 28
1990 40
1991 43
1992 44
1993 42
1994 48
1995 37
1996 50
1997 55
1998 61
1999 63
2000 61
2001 80
2002 83
2003 86
2004 82
2005 78
2006 91
2007 148
2008 190
2009 186
2010 199
2011 199
2012 199
2013 264
2014 399
2015 502
2016 549
2017 588
2018 585
2019 659
2020 739
2021 746
2022 665
2023 577
2024 308

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8,087 results

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13 articles found by citation matching

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Page 1
POLE, POLD1, and NTHL1: the last but not the least hereditary cancer-predisposing genes.
Magrin L, Fanale D, Brando C, Fiorino A, Corsini LR, Sciacchitano R, Filorizzo C, Dimino A, Russo A, Bazan V. Magrin L, et al. Oncogene. 2021 Oct;40(40):5893-5901. doi: 10.1038/s41388-021-01984-2. Epub 2021 Aug 6. Oncogene. 2021. PMID: 34363023 Review.
POLE, POLD1, and NTHL1 are involved in DNA replication and have recently been recognized as hereditary cancer-predisposing genes, because their alterations are associated with colorectal cancer and other tumors. ...Endometrial and breast cancers, and p
POLE, POLD1, and NTHL1 are involved in DNA replication and have recently been recognized as hereditary cancer-predisposing gen
POLE/POLD1 mutation and tumor immunotherapy.
Ma X, Dong L, Liu X, Ou K, Yang L. Ma X, et al. J Exp Clin Cancer Res. 2022 Jul 2;41(1):216. doi: 10.1186/s13046-022-02422-1. J Exp Clin Cancer Res. 2022. PMID: 35780178 Free PMC article. Review.
POLE/POLD1 exonuclease domain mutations lead to loss of proofreading function, which causes the accumulation of mutant genes in cells. ...This article reviews the function of POLE/POLD1, its relationship with deficient mismatch repair/high microsatellite instability
POLE/POLD1 exonuclease domain mutations lead to loss of proofreading function, which causes the accumulation of mutant genes in cells
Evaluation of treatment effects in patients with endometrial cancer and POLE mutations: An individual patient data meta-analysis.
McAlpine JN, Chiu DS, Nout RA, Church DN, Schmidt P, Lam S, Leung S, Bellone S, Wong A, Brucker SY, Lee CH, Clarke BA, Huntsman DG, Bernardini MQ, Ngeow J, Santin AD, Goodfellow P, Levine DA, Köbel M, Kommoss S, Bosse T, Gilks CB, Talhouk A. McAlpine JN, et al. Cancer. 2021 Jul 15;127(14):2409-2422. doi: 10.1002/cncr.33516. Epub 2021 Apr 1. Cancer. 2021. PMID: 33793971 Free article.
BACKGROUND: Endometrial cancers (ECs) with somatic mutations in DNA polymerase epsilon (POLE) are characterized by unfavorable pathological features, which prompt adjuvant treatment. ...Women who have endometrial cancers with true POLE mutations experi …
BACKGROUND: Endometrial cancers (ECs) with somatic mutations in DNA polymerase epsilon (POLE) are characterized by unfavorable …
Monocarboxylate transporters in cancer.
Payen VL, Mina E, Van Hée VF, Porporato PE, Sonveaux P. Payen VL, et al. Mol Metab. 2020 Mar;33:48-66. doi: 10.1016/j.molmet.2019.07.006. Epub 2019 Jul 27. Mol Metab. 2020. PMID: 31395464 Free PMC article. Review.
Glucose fuels glycolysis that can be coupled to the tricarboxylic acid (TCA) cycle and oxidative phosphorylation (OXPHOS) in oxidative cancer cells or to lactic fermentation in proliferating and in hypoxic cancer cells. ...This review summarizes the current knowledg …
Glucose fuels glycolysis that can be coupled to the tricarboxylic acid (TCA) cycle and oxidative phosphorylation (OXPHOS) in oxidative ca
Adjuvant therapy for endometrial cancer in the era of molecular classification: radiotherapy, chemoradiation and novel targets for therapy.
van den Heerik ASVM, Horeweg N, de Boer SM, Bosse T, Creutzberg CL. van den Heerik ASVM, et al. Int J Gynecol Cancer. 2021 Apr;31(4):594-604. doi: 10.1136/ijgc-2020-001822. Epub 2020 Oct 20. Int J Gynecol Cancer. 2021. PMID: 33082238 Free PMC article. Review.
For high-risk endometrial cancer, recent large randomized trials support the use of pelvic radiotherapy, especially in stage I-II endometrial cancer with risk factors. ...Recent molecular studies, most notably the work from The Cancer Genome Atlas (TCGA) proj …
For high-risk endometrial cancer, recent large randomized trials support the use of pelvic radiotherapy, especially in stage I-II end …
POLE proofreading defects: Contributions to mutagenesis and cancer.
Park VS, Pursell ZF. Park VS, et al. DNA Repair (Amst). 2019 Apr;76:50-59. doi: 10.1016/j.dnarep.2019.02.007. Epub 2019 Feb 16. DNA Repair (Amst). 2019. PMID: 30818169 Free PMC article. Review.
This review describes how mutations in these replication DNA polymerases help to drive mutagenesis and tumor development, with particular attention to DNA polymerase epsilon. Recent studies using cancer genome sequencing, mutational signature analyses, yeast and mouse mode …
This review describes how mutations in these replication DNA polymerases help to drive mutagenesis and tumor development, with particular at …
Incorporation of molecular characteristics into endometrial cancer management.
Vermij L, Smit V, Nout R, Bosse T. Vermij L, et al. Histopathology. 2020 Jan;76(1):52-63. doi: 10.1111/his.14015. Histopathology. 2020. PMID: 31846532 Free PMC article. Review.
Histopathological evaluation including subtyping and grading is the current cornerstone for endometrial cancer (EC) classification. This provides clinicians with prognostic information and input for further treatment recommendations. Nonetheless, patients with histological …
Histopathological evaluation including subtyping and grading is the current cornerstone for endometrial cancer (EC) classification. T …
Genetic Predisposition to Colorectal Cancer: How Many and Which Genes to Test?
Rebuzzi F, Ulivi P, Tedaldi G. Rebuzzi F, et al. Int J Mol Sci. 2023 Jan 21;24(3):2137. doi: 10.3390/ijms24032137. Int J Mol Sci. 2023. PMID: 36768460 Free PMC article. Review.
Colorectal cancer is one of the most common tumors, and genetic predisposition is one of the key risk factors in the development of this malignancy. ...Moreover, the recent advances in molecular techniques, in particular Next-Generation Sequencing, have led to the identifi …
Colorectal cancer is one of the most common tumors, and genetic predisposition is one of the key risk factors in the development of t …
p53abn Endometrial Cancer: understanding the most aggressive endometrial cancers in the era of molecular classification.
Jamieson A, Thompson EF, Huvila J, Gilks CB, McAlpine JN. Jamieson A, et al. Int J Gynecol Cancer. 2021 Jun;31(6):907-913. doi: 10.1136/ijgc-2020-002256. Epub 2021 Feb 15. Int J Gynecol Cancer. 2021. PMID: 33589443 Review.
In both systems there is a small subset of endometrial cancers (serous histotype/high numbers of somatic copy number abnormalities) that account for a disproportionately high percentage of endometrial cancer related deaths. ...Immunostaining for p53 stratifies the r …
In both systems there is a small subset of endometrial cancers (serous histotype/high numbers of somatic copy number abnormalities) t …
Impact of cancer metabolism on therapy resistance - Clinical implications.
Gonçalves AC, Richiardone E, Jorge J, Polónia B, Xavier CPR, Salaroglio IC, Riganti C, Vasconcelos MH, Corbet C, Sarmento-Ribeiro AB. Gonçalves AC, et al. Drug Resist Updat. 2021 Dec;59:100797. doi: 10.1016/j.drup.2021.100797. Epub 2021 Dec 16. Drug Resist Updat. 2021. PMID: 34955385 Free article. Review.
Furthermore, we report the role of TME-mediated intratumoral metabolic heterogeneity in therapy resistance and how adaptations in amino acid, glucose, and lipid metabolism support the growth of therapy-resistant cancers and/or cellular subpopulations. We also report the in …
Furthermore, we report the role of TME-mediated intratumoral metabolic heterogeneity in therapy resistance and how adaptations in amino acid …
8,087 results