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Did you mean prkcq cancer (189 results)?
Blocking Interleukin (IL)4- and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer.
Rahal OM, Wolfe AR, Mandal PK, Larson R, Tin S, Jimenez C, Zhang D, Horton J, Reuben JM, McMurray JS, Woodward WA. Rahal OM, et al. Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):1034-1043. doi: 10.1016/j.ijrobp.2017.11.043. Epub 2017 Dec 7. Int J Radiat Oncol Biol Phys. 2018. PMID: 29485045 Free article.
PURPOSE: To determine the role of macrophage polarization on the response of inflammatory breast cancer (IBC) cells to radiation and whether modulation of macrophage plasticity can alter radiation response. ...KPL4 cells with stable short hairpin RNA knockdown of PRKCZ …
PURPOSE: To determine the role of macrophage polarization on the response of inflammatory breast cancer (IBC) cells to radiation and …
RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones.
Della Peruta M, Giagulli C, Laudanna C, Scarpa A, Sorio C. Della Peruta M, et al. Mol Cancer. 2010 Mar 17;9:61. doi: 10.1186/1476-4598-9-61. Mol Cancer. 2010. PMID: 20236512 Free PMC article.
BACKGROUND: Our understanding of the mechanism regulating pancreatic cancer metastatic phenotype is limited. We analyzed the role of RHOA and PRKCZ in the motility attitude of two subclones of the pancreatic adenocarcinoma cell line SUIT-2 (S2), with different in vi …
BACKGROUND: Our understanding of the mechanism regulating pancreatic cancer metastatic phenotype is limited. We analyzed the role of …
PRKCZ-AS1 promotes the tumorigenesis of lung adenocarcinoma via sponging miR-766-5p to modulate MAPK1.
Wang M, Liao Q, Zou P. Wang M, et al. Cancer Biol Ther. 2020 Apr 2;21(4):364-371. doi: 10.1080/15384047.2019.1702402. Epub 2020 Jan 15. Cancer Biol Ther. 2020. PMID: 31939714 Free PMC article.
Nevertheless, limited research has been carried on the function of PRKCZ-AS1 in LUAD. In this study, the expression of PRKCZ-AS1 in LUAD tissues and cell lines was notably upregulated. ...Furthermore, miR-766-5p could bind with PRKCZ-AS1. Besides, the express …
Nevertheless, limited research has been carried on the function of PRKCZ-AS1 in LUAD. In this study, the expression of PRKCZ-A …
Hypermethylation of PRKCZ Regulated by E6 Inhibits Invasion and EMT via Cdc42 in HPV-Related Head and Neck Squamous Cell Carcinoma.
Wang HF, Jiang J, Wu JS, Zhang M, Pang X, Dai L, Tang YL, Liang XH. Wang HF, et al. Cancers (Basel). 2022 Aug 27;14(17):4151. doi: 10.3390/cancers14174151. Cancers (Basel). 2022. PMID: 36077689 Free PMC article.
PRKCZ was hypermethylated in HPV+ HNSCC patients, and PRKCZ methylation status was negatively related to the pathological grading of HNSCC patients. Silencing PRKCZ inhibited the malignant capacity of HPV+ HNSCC cells. Mechanistically, HPV might promote DNMT1 …
PRKCZ was hypermethylated in HPV+ HNSCC patients, and PRKCZ methylation status was negatively related to the pathological grad …
Identification of Prognostic Biomarkers for Bladder Cancer Based on DNA Methylation Profile.
Zhang S, Zhang J, Zhang Q, Liang Y, Du Y, Wang G. Zhang S, et al. Front Cell Dev Biol. 2022 Jan 31;9:817086. doi: 10.3389/fcell.2021.817086. eCollection 2021. Front Cell Dev Biol. 2022. PMID: 35174173 Free PMC article.
Results: In this study, we found that DNA methylation was indeed related with the occurrence of bladder cancer. Genes with differential DNA methylation could serve as potential biomarkers for bladder cancer. Through univariate and multivariate Cox proportional hazar …
Results: In this study, we found that DNA methylation was indeed related with the occurrence of bladder cancer. Genes with differenti …
Atypical protein kinase C zeta: potential player in cell survival and cell migration of ovarian cancer.
Seto KK, Andrulis IL. Seto KK, et al. PLoS One. 2015 Apr 14;10(4):e0123528. doi: 10.1371/journal.pone.0123528. eCollection 2015. PLoS One. 2015. PMID: 25874946 Free PMC article.
Ovarian cancer is one of the most aggressive gynaecological cancers, thus understanding the different biological pathways involved in ovarian cancer progression is important in identifying potential therapeutic targets for the disease. The aim of this study w …
Ovarian cancer is one of the most aggressive gynaecological cancers, thus understanding the different biological pathways invo …
Methylation-mediated silencing of protein kinase C zeta induces apoptosis avoidance through ATM/CHK2 inactivation in dedifferentiated chondrosarcoma.
Shimada E, Matsumoto Y, Nakagawa M, Susuki Y, Endo M, Setsu N, Fujiwara T, Iida K, Nabeshima A, Yahiro K, Kimura A, Hirose T, Kanahori M, Oyama R, Oda Y, Nakashima Y. Shimada E, et al. Br J Cancer. 2022 May;126(9):1289-1300. doi: 10.1038/s41416-021-01695-1. Epub 2022 Jan 11. Br J Cancer. 2022. PMID: 35017658 Free PMC article.
Decitabine increased PRKCZ expression through de-methylating the promoter region of PRKCZ, which activated the ATM/CHK2 pathway and inhibited cell proliferation by inducing apoptosis. ...Decitabine-induced expression of PRKCZ represents a promising therapy fo …
Decitabine increased PRKCZ expression through de-methylating the promoter region of PRKCZ, which activated the ATM/CHK2 pathwa …
scBPGRN: Integrating single-cell multi-omics data to construct gene regulatory networks based on BP neural network.
Xuan C, Wang Y, Zhang B, Wu H, Ding T, Gao J. Xuan C, et al. Comput Biol Med. 2022 Dec;151(Pt A):106249. doi: 10.1016/j.compbiomed.2022.106249. Epub 2022 Oct 28. Comput Biol Med. 2022. PMID: 36335815
The deterioration and metastasis of cancer involve various aspects of genomic changes, including genomic DNA changes, epigenetic modifications, gene expression, and other complex interactions. ...Finally, the node strength is calculated to identify the genes associated wit …
The deterioration and metastasis of cancer involve various aspects of genomic changes, including genomic DNA changes, epigenetic modi …
Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers.
Reimand J, Bader GD. Reimand J, et al. Mol Syst Biol. 2013;9:637. doi: 10.1038/msb.2012.68. Mol Syst Biol. 2013. PMID: 23340843 Free PMC article.
Our findings include multiple actionable cancer gene candidates (FLNB, GRM1, POU2F1), protein complexes (HCF1, ASF1), and kinases (PRKCZ). This study demonstrates new ways of interpreting cancer genomes and presents new leads for cancer research....
Our findings include multiple actionable cancer gene candidates (FLNB, GRM1, POU2F1), protein complexes (HCF1, ASF1), and kinases ( …
Pan-Cancer Study on Protein Kinase C Family as a Potential Biomarker for the Tumors Immune Landscape and the Response to Immunotherapy.
Abdelatty A, Sun Q, Hu J, Wu F, Wei G, Xu H, Zhou G, Wang X, Xia H, Lan L. Abdelatty A, et al. Front Cell Dev Biol. 2022 Jan 31;9:798319. doi: 10.3389/fcell.2021.798319. eCollection 2021. Front Cell Dev Biol. 2022. PMID: 35174160 Free PMC article.
Univariate and multivariate Cox analysis was performed to evaluate the prognostic role of PKC genes in cancers. Methylation level and CNAs could drive the expression levels of some PKC members, especially PRKCI, whose CNGs are predicted to elevate their level in many ca …
Univariate and multivariate Cox analysis was performed to evaluate the prognostic role of PKC genes in cancers. Methylation level and …
40 results