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2020 1
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The integration of single-cell sequencing, TCGA, and GEO data analysis revealed that PRRT3-AS1 is a biomarker and therapeutic target of SKCM.
Zhang W, Xie X, Huang Z, Zhong X, Liu Y, Cheong KL, Zhou J, Tang S. Zhang W, et al. Front Immunol. 2022 Sep 23;13:919145. doi: 10.3389/fimmu.2022.919145. eCollection 2022. Front Immunol. 2022. PMID: 36211371 Free PMC article.
Cellular function experiments in vitro revealed that PRRT3-AS1 may be required for cancer cell migration in SKCM. PRRT3-AS1 was found to be related to epithelial-mesenchymal transition (EMT) signaling pathways. DNA methylation of PRRT3-AS1 was negative …
Cellular function experiments in vitro revealed that PRRT3-AS1 may be required for cancer cell migration in SKCM. PRRT3 …
LncRNA PRRT3-AS1 exerts oncogenic effects on nonsmall cell lung cancer by targeting microRNA-507/homeobox B5 axis.
Zhou R, Xu J, Wang L, Li J. Zhou R, et al. Oncol Res. 2022 Nov 10;29(6):411-423. doi: 10.32604/or.2022.026236. eCollection 2021. Oncol Res. 2022. PMID: 37304647 Free PMC article.
Long noncoding RNAs (lncRNAs) act as key regulators controlling complex cellular behaviors in nonsmall cell lung cancer (NSCLC). We investigated the expression of lncRNA PRRT3 antisense RNA 1 (PRRT3-AS1) in paired samples of NSCLC and adjacent normal tissues …
Long noncoding RNAs (lncRNAs) act as key regulators controlling complex cellular behaviors in nonsmall cell lung cancer (NSCLC). We i …
Long non-coding RNA PRRT3-AS1 silencing inhibits prostate cancer cell proliferation and promotes apoptosis and autophagy.
Fan L, Li H, Wang W. Fan L, et al. Exp Physiol. 2020 May;105(5):793-808. doi: 10.1113/EP088011. Epub 2020 Apr 22. Exp Physiol. 2020. PMID: 32086850 Free article.
Further work is needed to consolidate the therapeutic value of lncRNA PRRT3-AS1 in clinical trials and treatment of prostate cancer. ABSTRACT: Although long non-coding RNAs (lncRNAs) are correlated with multiple cancers, their molecular mechanisms in prostate …
Further work is needed to consolidate the therapeutic value of lncRNA PRRT3-AS1 in clinical trials and treatment of prostate cance …
Individualized lncRNA differential expression profile reveals heterogeneity of breast cancer.
Zhao Z, Guo Y, Liu Y, Sun L, Chen B, Wang C, Chen T, Wang Y, Li Y, Dong Q, Ai L, Wang R, Gu Y, Li X. Zhao Z, et al. Oncogene. 2021 Jul;40(27):4604-4614. doi: 10.1038/s41388-021-01883-6. Epub 2021 Jun 15. Oncogene. 2021. PMID: 34131286 Free PMC article.
Long non-coding RNAs (lncRNAs) play key regulatory roles in breast cancer. However, population-level differential expression analysis methods disregard the heterogeneous expression of lncRNAs in individual patients. ...Last, drug response analysis revealed lncRNA ENSG00000 …
Long non-coding RNAs (lncRNAs) play key regulatory roles in breast cancer. However, population-level differential expression analysis …
Identification of CNGB1 as a Predictor of Response to Neoadjuvant Chemotherapy in Muscle-Invasive Bladder Cancer.
Hepburn AC, Lazzarini N, Veeratterapillay R, Wilson L, Bacardit J, Heer R. Hepburn AC, et al. Cancers (Basel). 2021 Aug 2;13(15):3903. doi: 10.3390/cancers13153903. Cancers (Basel). 2021. PMID: 34359804 Free PMC article.
Cisplatin-based neoadjuvant chemotherapy (NAC) is recommended prior to radical cystectomy for muscle-invasive bladder cancer (MIBC) patients. Despite a 5-10% survival benefit, some patients do not respond and experience substantial toxicity and delay in surgery. ...Kaplan- …
Cisplatin-based neoadjuvant chemotherapy (NAC) is recommended prior to radical cystectomy for muscle-invasive bladder cancer (MIBC) p …
Insight on the hub gene associated signatures and potential therapeutic agents in epilepsy and glioma.
Zhao K, Bai X, Wang X, Cao Y, Zhang L, Li W, Wang S. Zhao K, et al. Brain Res Bull. 2023 Jul;199:110666. doi: 10.1016/j.brainresbull.2023.110666. Epub 2023 May 14. Brain Res Bull. 2023. PMID: 37192718 Free article.
We used lasso regression model to reduce 88 characteristic genes, and finally screened out 14 genes (EIF4A2, CEP170B, SNPH, EPHA4, KLK7, GNG3, MYOP, ANKRD29, RASD2, PRRT3, EFR3A, SGIP1, RAB6B, CNNM1) as the features of glioma prognosis model whose ROC curve is 0.9. Then, w …
We used lasso regression model to reduce 88 characteristic genes, and finally screened out 14 genes (EIF4A2, CEP170B, SNPH, EPHA4, KLK7, GNG …
Construction and Validation of a Ferroptosis-Related lncRNA Signature as a Novel Biomarker for Prognosis, Immunotherapy and Targeted Therapy in Hepatocellular Carcinoma.
Zhang Z, Zhang W, Wang Y, Wan T, Hu B, Li C, Ge X, Lu S. Zhang Z, et al. Front Cell Dev Biol. 2022 Feb 22;10:792676. doi: 10.3389/fcell.2022.792676. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35295858 Free PMC article.
Least Absolute Shrinkage and Selection Operator (LASSO) regression and Cox regression analyses were used to screen the six FR-lncRNAs (including MKLN1-AS, LINC01224, LNCSRLR, LINC01063, PRRT3-AS1, and POLH-AS1). Kaplan-Meier (K-M) and receiver operating characteristic (ROC …
Least Absolute Shrinkage and Selection Operator (LASSO) regression and Cox regression analyses were used to screen the six FR-lncRNAs (inclu …
Identification of biomarkers of hepatocellular carcinoma gene prognosis based on the immune-related lncRNA signature of transcriptome data.
Ma A, Sun Y, Ogbodu RO, Xiao L, Deng H, Zhou H. Ma A, et al. Funct Integr Genomics. 2023 Mar 28;23(2):104. doi: 10.1007/s10142-023-01019-x. Funct Integr Genomics. 2023. PMID: 36976410 Retracted.
METHODS: The developed lncRNA signature was validated using 343 HCC patients from The Cancer Genome Atlas (TCGA) and 81 samples from Gene Expression Omnibus (GEO). ...After PRRT3-AS1 knockdown, the protein expression of CD24, THY1, LYN, CD47, and TRAF2 in HepG2 cell …
METHODS: The developed lncRNA signature was validated using 343 HCC patients from The Cancer Genome Atlas (TCGA) and 81 samples from …
Construction and verification of a novel circadian clock related long non-coding RNA model and prediction of treatment for survival prognosis in patients with hepatocellular carcinoma.
Zhang Z, Gao W, Tan X, Deng T, Zhou W, Jian H, Zeng P. Zhang Z, et al. BMC Cancer. 2023 Jan 17;23(1):57. doi: 10.1186/s12885-023-10508-y. BMC Cancer. 2023. PMID: 36647032 Free PMC article.
Circadian clock-related lncRNAs expressed in HCC were extracted from The Cancer Genome Atlas. A nomogram was established to predict individual survival rate. ...Further GDSC analysis indicated that patients in each risk score group may be sensitive to different anti-can …
Circadian clock-related lncRNAs expressed in HCC were extracted from The Cancer Genome Atlas. A nomogram was established to predict i …
Development and validation of a set of novel and robust 4-lncRNA-based nomogram predicting prostate cancer survival by bioinformatics analysis.
Zhang P, Tan X, Zhang D, Gong Q, Zhang X. Zhang P, et al. PLoS One. 2021 May 4;16(5):e0249951. doi: 10.1371/journal.pone.0249951. eCollection 2021. PLoS One. 2021. PMID: 33945533 Free PMC article.
BACKGROUND AND OBJECTIVE: Accumulating evidence shows that long noncoding RNAs (lncRNAs) possess great potential in the diagnosis and prognosis of prostate cancer (PCa). Therefore, this study aimed to construct an lncRNA-based signature to more accurately predict the progn …
BACKGROUND AND OBJECTIVE: Accumulating evidence shows that long noncoding RNAs (lncRNAs) possess great potential in the diagnosis and progno …
12 results