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Year Number of Results
1991 1
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2008 1
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2012 1
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2014 1
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49 results

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In PD-1+ human colon cancer cells NIVOLUMAB promotes survival and could protect tumor cells from conventional therapies.
Ieranò C, Righelli D, D'Alterio C, Napolitano M, Portella L, Rea G, Auletta F, Santagata S, Trotta AM, Guardascione G, Liotti F, Prevete N, Maiolino P, Luciano A, Barbieri A, Di Mauro A, Roma C, Esposito Abate R, Tatangelo F, Pacelli R, Normanno N, Melillo RM, Scala S. Ieranò C, et al. J Immunother Cancer. 2022 Mar;10(3):e004032. doi: 10.1136/jitc-2021-004032. J Immunother Cancer. 2022. PMID: 35246475 Free PMC article.
Transcriptional profile of NIVO-treated HT29 and HCT116 human colon cancer cells revealed downregulation of BATF2, DRAM1, FXYD3, IFIT3, MT-TN, and TNFRSF11A, and upregulation of CLK1, DCAF13, DNAJC2, MTHFD1L, PRPF3, PSMD7, and SCFD1; the opposite regulation was described i …
Transcriptional profile of NIVO-treated HT29 and HCT116 human colon cancer cells revealed downregulation of BATF2, DRAM1, FXYD3, IFIT3, MT-T …
Transcriptional activation of Proteasome 26S non-ATPase subunit 7 by forkhead box P3 participates in gastric cancer cell proliferation and apoptosis.
Xu Y, Wang D, Zhao G. Xu Y, et al. Bioengineered. 2022 Feb;13(2):2525-2536. doi: 10.1080/21655979.2021.2018097. Bioengineered. 2022. PMID: 35037550 Free PMC article.
FOXP3 was also predicted to have binding sites on PSMD7 promoter. Thus, this study investigated the relationship between PSMD7 and FOXP3 and their roles in gastric cancer. ...FOXP3 was found to bind to PSMD7 promoter and activate PSMD7 expression. Over …
FOXP3 was also predicted to have binding sites on PSMD7 promoter. Thus, this study investigated the relationship between PSMD7 …
Deubiquitinase PSMD7 facilitates pancreatic cancer progression through activating Nocth1 pathway via modifying SOX2 degradation.
Luo C, Yu Y, Zhu J, Chen L, Li D, Peng X, Liu Z, Li Q, Cao Q, Huang K, Yuan R. Luo C, et al. Cell Biosci. 2024 Mar 17;14(1):35. doi: 10.1186/s13578-024-01213-9. Cell Biosci. 2024. PMID: 38494478 Free PMC article.
However, the clinical significance and biological functions of PSMD7 in pancreatic cancer (PC) remain unclear. RESULTS: In this study, we first reported frequent overexpression of PSMD7 in PC tissues, and high levels of PSMD7 were markedly linked to shorter s …
However, the clinical significance and biological functions of PSMD7 in pancreatic cancer (PC) remain unclear. RESULTS: In this study …
PSMD7 downregulation suppresses lung cancer progression by regulating the p53 pathway.
Xu X, Xuan X, Zhang J, Xu H, Yang X, Zhang L, Zhao Y, Xu H, Li D. Xu X, et al. J Cancer. 2021 Jun 11;12(16):4945-4957. doi: 10.7150/jca.53613. eCollection 2021. J Cancer. 2021. PMID: 34234864 Free PMC article.
In this study, we assessed PSMD7 expression and investigated the underlying molecular events by which PSMD7 regulates tumor progression in non-small cell lung cancer (NSCLC). ...PSMD7 knockdown inhibited expression of a set of proteins regulating cell cycle p …
In this study, we assessed PSMD7 expression and investigated the underlying molecular events by which PSMD7 regulates tumor pr …
Deubiquitinase PSMD7 promotes the proliferation, invasion, and cisplatin resistance of gastric cancer cells by stabilizing RAD23B.
Wang J, Liu R, Mo H, Xiao X, Xu Q, Zhao W. Wang J, et al. Int J Biol Sci. 2021 Jul 25;17(13):3331-3342. doi: 10.7150/ijbs.61128. eCollection 2021. Int J Biol Sci. 2021. PMID: 34512150 Free PMC article.
Elevated levels of PSMD7 were also detected in GC cell lines. Notably, the upregulation of PSMD7 closely correlated with malignant clinical parameters and reduced the survival of GC patients. ...Ectopic expression of PSMD7 facilitated GC cell proliferation an …
Elevated levels of PSMD7 were also detected in GC cell lines. Notably, the upregulation of PSMD7 closely correlated with malig …
Deubiquitinating enzyme PSMD7 promotes bladder cancer development: Involvement of RAB1A stabilization.
Wang J, Wang T, Feng YK, Liu Y, Fu B, Liu XT, Wu QZ. Wang J, et al. Cell Signal. 2024 Feb;114:110996. doi: 10.1016/j.cellsig.2023.110996. Epub 2023 Nov 30. Cell Signal. 2024. PMID: 38040402
To investigate the functional role of PSMD7, two BC cell lines, T24 and 5637, were selected. The cells were transfected with vectors containing short hairpin RNAs against PSMD7 or plasmids containing full-length PSMD7 to knockdown or overexpress PSMD7. …
To investigate the functional role of PSMD7, two BC cell lines, T24 and 5637, were selected. The cells were transfected with vectors …
Novel insights into the non-canonical roles of PSMD14/POH1/Rpn11 in proteostasis and in the modulation of cancer progression.
Bustamante HA, Albornoz N, Morselli E, Soza A, Burgos PV. Bustamante HA, et al. Cell Signal. 2023 Jan;101:110490. doi: 10.1016/j.cellsig.2022.110490. Epub 2022 Oct 12. Cell Signal. 2023. PMID: 36241058
During the assembly of the lid, activity of PSMD14 has been detected in the context of the heterodimer with PSMD7. Additionally, assembly of the lid subcomplex occurs as an independent event of the base subcomplex and 20S proteasome. This feature opens the possibility that …
During the assembly of the lid, activity of PSMD14 has been detected in the context of the heterodimer with PSMD7. Additionally, asse …
Deubiquitinase PSMD7 regulates cell fate and is associated with disease progression in breast cancer.
Zhao Y, Yang X, Xu X, Zhang J, Zhang L, Xu H, Miao Z, Li D, Wang S. Zhao Y, et al. Am J Transl Res. 2020 Sep 15;12(9):5433-5448. eCollection 2020. Am J Transl Res. 2020. PMID: 33042429 Free PMC article.
In this study, we assessed the level of PSMD7 in breast cancer tissues and investigated the underlying molecular events by which PSMD7 could play a role in tumor progression. The results showed that the PSMD7 level was significantly upregulated in breast canc …
In this study, we assessed the level of PSMD7 in breast cancer tissues and investigated the underlying molecular events by which P …
Identification of PSMD7 as a prognostic factor correlated with immune infiltration in head and neck squamous cell carcinoma.
Zhang S, Yu S, Wang J, Cheng Z. Zhang S, et al. Biosci Rep. 2021 Mar 26;41(3):BSR20203829. doi: 10.1042/BSR20203829. Biosci Rep. 2021. PMID: 33687056 Free PMC article.
High expression of PSMD7 suggested inferior survival of HNSCC patients. GSEA and CERES score indicated that PSMD7 was closely correlated with tumor-related signaling pathways and cell survival. ...Moreover, PSMD7 influenced the prognosis of HNSCC patients par …
High expression of PSMD7 suggested inferior survival of HNSCC patients. GSEA and CERES score indicated that PSMD7 was closely …
PSMD7 downregulation induces apoptosis and suppresses tumorigenesis of esophageal squamous cell carcinoma via the mTOR/p70S6K pathway.
Shi K, Zhang JZ, Zhao RL, Yang L, Guo D. Shi K, et al. FEBS Open Bio. 2018 Mar 7;8(4):533-543. doi: 10.1002/2211-5463.12394. eCollection 2018 Apr. FEBS Open Bio. 2018. PMID: 29632807 Free PMC article.
PSMD7, a 19S proteasome subunit, is overexpressed in most carcinoma cells. ...Our results showed that PSMD7 was highly expressed in ESCC cells. Downregulation of PSMD7 by lentivirus-mediated shRNA led to decreased proliferation, increased cell apoptosis, and …
PSMD7, a 19S proteasome subunit, is overexpressed in most carcinoma cells. ...Our results showed that PSMD7 was highly express …
49 results