Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1998 1
2003 1
2005 3
2006 3
2007 3
2008 4
2009 6
2010 5
2011 8
2012 11
2013 10
2014 12
2015 11
2016 7
2017 11
2018 10
2019 9
2020 12
2021 17
2022 24
2023 15
2024 5

Text availability

Article attribute

Article type

Publication date

Search Results

174 results

Results by year

Filters applied: . Clear all
Page 1
An integrative prognostic and immune analysis of PTPRD in cancer.
Ou C, Peng Q, Zeng C. Ou C, et al. Math Biosci Eng. 2022 Mar 25;19(6):5361-5379. doi: 10.3934/mbe.2022251. Math Biosci Eng. 2022. PMID: 35603359 Free article.
GO and KEGG enrichment analysis was executed by the Metascape database. A correlation between PTPRD expression and prognosis was found in various cancers. Aberrant PTPRD expression was closely related to immune infiltration. ...Functional enrichment analysis …
GO and KEGG enrichment analysis was executed by the Metascape database. A correlation between PTPRD expression and prognosis was foun …
DIAPH2, PTPRD and HIC1 Gene Polymorphisms and Laryngeal Cancer Risk.
Śnit M, Misiołek M, Ścierski W, Koniewska A, Stryjewska-Makuch G, Okła S, Grzeszczak W. Śnit M, et al. Int J Environ Res Public Health. 2021 Jul 13;18(14):7486. doi: 10.3390/ijerph18147486. Int J Environ Res Public Health. 2021. PMID: 34299935 Free PMC article.
This study was designed to assess the association between DIAPH2, PTPRD and HIC1 SNPs and laryngeal cancer risk. PATIENTS AND METHODS: This study including 267 patients with histologically confirmed laryngeal cancer and 157 controls. ...Statistical analysis t …
This study was designed to assess the association between DIAPH2, PTPRD and HIC1 SNPs and laryngeal cancer risk. PATIENTS AND …
Manipulating PTPRD function with ectodomain antibodies.
Qian Z, Song D, Ipsaro JJ, Bautista C, Joshua-Tor L, Yeh JT, Tonks NK. Qian Z, et al. Genes Dev. 2023 Aug 1;37(15-16):743-759. doi: 10.1101/gad.350713.123. Epub 2023 Sep 5. Genes Dev. 2023. PMID: 37669874 Free PMC article.
We have validated antibody binding to endogenous PTPRD in a metastatic breast cancer cell line, CAL51, and demonstrated that a monoclonal antibody, RD-43, inhibited phosphatase activity and induced the degradation of PTPRD. Similar effects were observed follo …
We have validated antibody binding to endogenous PTPRD in a metastatic breast cancer cell line, CAL51, and demonstrated that a …
PTPRD/PTPRT mutation as a predictive biomarker of immune checkpoint inhibitors across multiple cancer types.
Shang X, Zhang W, Zhang X, Yu M, Liu J, Cheng Y, Cheng B. Shang X, et al. Front Immunol. 2022 Sep 29;13:991091. doi: 10.3389/fimmu.2022.991091. eCollection 2022. Front Immunol. 2022. PMID: 36248841 Free PMC article.
PTPRD and PTPRT (PTPRD/PTPRT) are the phosphatases of JAK-STAT signaling, a critical pathway in anti-cancer immunity regulation. However, the pan-cancer association between PTPRD/PTPRT mutation and the efficacy of ICIs remains unclear across pan …
PTPRD and PTPRT (PTPRD/PTPRT) are the phosphatases of JAK-STAT signaling, a critical pathway in anti-cancer immunity re …
Marginal zone lymphomas.
Zucca E, Rossi D, Bertoni F. Zucca E, et al. Hematol Oncol. 2023 Jun;41 Suppl 1:88-91. doi: 10.1002/hon.3152. Hematol Oncol. 2023. PMID: 37294969 Review.
However, they differ in the presence of recurrent translocations, mutations affecting the Notch signaling pathway (NOTCH2 and less commonly NOTCH1), the transcription factors Kruppel-like factor 2 (KLF2) or the receptor-type protein tyrosine phosphatase delta (PTPRD). This …
However, they differ in the presence of recurrent translocations, mutations affecting the Notch signaling pathway (NOTCH2 and less commonly …
PTPRD-inactivation-induced CXCL8 promotes angiogenesis and metastasis in gastric cancer and is inhibited by metformin.
Bae WJ, Ahn JM, Byeon HE, Kim S, Lee D. Bae WJ, et al. J Exp Clin Cancer Res. 2019 Dec 5;38(1):484. doi: 10.1186/s13046-019-1469-4. J Exp Clin Cancer Res. 2019. PMID: 31805999 Free PMC article.
BACKGROUND: Protein tyrosine phosphatase receptor delta (PTPRD) is frequently inactivated in various types of cancers. Here, we explored the underlying mechanism of PTPRD-loss-induced cancer metastasis and investigated an efficient treatment option for …
BACKGROUND: Protein tyrosine phosphatase receptor delta (PTPRD) is frequently inactivated in various types of cancers. Here, w …
PTPRD/PTPRT mutation correlates to treatment outcomes of immunotherapy and immune landscape in pan-cancers.
Wang G, Ji X, Wang H, Tang X, Xing X, Ji J. Wang G, et al. Chin J Cancer Res. 2023 Jun 30;35(3):316-330. doi: 10.21147/j.issn.1000-9604.2023.03.09. Chin J Cancer Res. 2023. PMID: 37440827 Free PMC article.
Then, the association between PTPRD/PTPRT mutation and immune profiles was analyzed using The Cancer Genome Atlas (TCGA) cohort. ...CONCLUSIONS: PTPRD/PTPRT mutation could serve as a potential predictive biomarker for cancer immunotherapy....
Then, the association between PTPRD/PTPRT mutation and immune profiles was analyzed using The Cancer Genome Atlas (TCGA) cohor …
Identification of key genes associated with polycystic ovary syndrome (PCOS) and ovarian cancer using an integrated bioinformatics analysis.
Zou J, Li Y, Liao N, Liu J, Zhang Q, Luo M, Xiao J, Chen Y, Wang M, Chen K, Zeng J, Mo Z. Zou J, et al. J Ovarian Res. 2022 Feb 28;15(1):30. doi: 10.1186/s13048-022-00962-w. J Ovarian Res. 2022. PMID: 35227296 Free PMC article.
BACKGROUND: Accumulating evidence suggests a strong association between polycystic ovary syndrome (PCOS) and ovarian cancer (OC), but the potential molecular mechanism remains unclear. ...Twelve genes, including RNF144B, LPAR3, CRISPLD2, JCHAIN, OR7E14P, IL27RA, PTPRD …
BACKGROUND: Accumulating evidence suggests a strong association between polycystic ovary syndrome (PCOS) and ovarian cancer (OC), but …
Tyrosine phosphatase PTPRD suppresses colon cancer cell migration in coordination with CD44.
Funato K, Yamazumi Y, Oda T, Akiyama T. Funato K, et al. Exp Ther Med. 2011 May;2(3):457-463. doi: 10.3892/etm.2011.231. Epub 2011 Mar 21. Exp Ther Med. 2011. PMID: 22977525 Free PMC article.
However, the molecular functions of PTPRD in cancer progression have yet to be elucidated. Herein, PTPRD suppressed colon cancer cell migration and was required for appropriate cell-cell adhesion. ...Our findings suggest that PTPRD is required f …
However, the molecular functions of PTPRD in cancer progression have yet to be elucidated. Herein, PTPRD suppressed col …
Reduced expression of PTPRD correlates with poor prognosis in gastric adenocarcinoma.
Wang D, Wang L, Zhou J, Pan J, Qian W, Fu J, Zhang G, Zhu Y, Liu C, Wang C, Jin Z, He Z, Wu J, Shi B. Wang D, et al. PLoS One. 2014 Nov 20;9(11):e113754. doi: 10.1371/journal.pone.0113754. eCollection 2014. PLoS One. 2014. PMID: 25412184 Free PMC article.
Cox regression analysis confirmed PTPRD expression as independent predictor of the overall survival of gastric cancer patients. ...CONCLUSIONS: These results indicated that PTPRD is a candidate tumour suppressor in gastric cancer. Thus, PTPRD ma …
Cox regression analysis confirmed PTPRD expression as independent predictor of the overall survival of gastric cancer patients …
174 results