Pacheco-Quinto J - Search Results

1

Intracellular metalloprotease activity controls intraneuronal Aβ aggregation and limits secretion of Aβ via exosomes.

Pacheco-Quinto J, Clausen D, Pérez-González R, Peng H, Meszaros A, Eckman CB, Levy E, Eckman EA. Pacheco-Quinto J, et al. FASEB J. 2019 Mar;33(3):3758-3771. doi: 10.1096/fj.201801319R. Epub 2018 Nov 27. FASEB J. 2019. PMID: 30481490 Free PMC article.

2

Endothelin-converting enzymes and related metalloproteases in Alzheimer's disease.

Pacheco-Quinto J, Herdt A, Eckman CB, Eckman EA. Pacheco-Quinto J, et al. J Alzheimers Dis. 2013;33 Suppl 1(0 1):S101-10. doi: 10.3233/JAD-2012-129043. J Alzheimers Dis. 2013. PMID: 22903130 Free PMC article. Review.

3

Endothelin-converting enzymes degrade intracellular β-amyloid produced within the endosomal/lysosomal pathway and autophagosomes.

Pacheco-Quinto J, Eckman EA. Pacheco-Quinto J, et al. J Biol Chem. 2013 Feb 22;288(8):5606-15. doi: 10.1074/jbc.M112.422964. Epub 2013 Jan 2. J Biol Chem. 2013. PMID: 23283972 Free PMC article.

4

Evidence of a novel mechanism for partial γ-secretase inhibition induced paradoxical increase in secreted amyloid β protein.

Barnwell E, Padmaraju V, Baranello R, Pacheco-Quinto J, Crosson C, Ablonczy Z, Eckman E, Eckman CB, Ramakrishnan V, Greig NH, Pappolla MA, Sambamurti K. Barnwell E, et al. Among authors: pacheco quinto j. PLoS One. 2014 Mar 21;9(3):e91531. doi: 10.1371/journal.pone.0091531. eCollection 2014. PLoS One. 2014. PMID: 24658363 Free PMC article.

5

Major amyloid-β-degrading enzymes, endothelin-converting enzyme-2 and neprilysin, are expressed by distinct populations of GABAergic interneurons in hippocampus and neocortex.

Pacheco-Quinto J, Eckman CB, Eckman EA. Pacheco-Quinto J, et al. Neurobiol Aging. 2016 Dec;48:83-92. doi: 10.1016/j.neurobiolaging.2016.08.011. Epub 2016 Aug 20. Neurobiol Aging. 2016. PMID: 27644077 Free PMC article.

6

Neuroimmunomodulators in Neuroborreliosis and Lyme Encephalopathy.

Eckman EA, Pacheco-Quinto J, Herdt AR, Halperin JJ. Eckman EA, et al. Among authors: pacheco quinto j. Clin Infect Dis. 2018 Jun 18;67(1):80-88. doi: 10.1093/cid/ciy019. Clin Infect Dis. 2018. PMID: 29340592

7

Specificity and Diagnostic Utility of Cerebrospinal Fluid CXCL13 in Lyme Neuroborreliosis.

Eckman EA, Clausen DM, Herdt AR, Pacheco-Quinto J, Halperin JJ. Eckman EA, et al. Among authors: pacheco quinto j. Clin Infect Dis. 2021 May 18;72(10):1719-1726. doi: 10.1093/cid/ciaa335. Clin Infect Dis. 2021. PMID: 32221538

8

Extracellular vesicles: where the amyloid precursor protein carboxyl-terminal fragments accumulate and amyloid-β oligomerizes.

Pérez-González R, Kim Y, Miller C, Pacheco-Quinto J, Eckman EA, Levy E. Pérez-González R, et al. Among authors: pacheco quinto j. FASEB J. 2020 Sep;34(9):12922-12931. doi: 10.1096/fj.202000823R. Epub 2020 Aug 9. FASEB J. 2020. PMID: 32772431 Free PMC article.

9

Nascent Aβ42 Fibrillization in Synaptic Endosomes Precedes Plaque Formation in a Mouse Model of Alzheimer's-like β-Amyloidosis.

Eckman EA, Clausen DM, Solé-Domėnech S, Lee CW, Sinobas-Pereira C, Domalewski RJ, Nichols MR, Pacheco-Quinto J. Eckman EA, et al. Among authors: pacheco quinto j. J Neurosci. 2023 Dec 13;43(50):8812-8824. doi: 10.1523/JNEUROSCI.1318-23.2023. J Neurosci. 2023. PMID: 37884349

10

Evidence for lymphatic Aβ clearance in Alzheimer's transgenic mice.

Pappolla M, Sambamurti K, Vidal R, Pacheco-Quinto J, Poeggeler B, Matsubara E. Pappolla M, et al. Among authors: pacheco quinto j. Neurobiol Dis. 2014 Nov;71:215-9. doi: 10.1016/j.nbd.2014.07.012. Epub 2014 Aug 4. Neurobiol Dis. 2014. PMID: 25102344 Free PMC article.

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