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Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties.
Urs NM, Gee SM, Pack TF, McCorvy JD, Evron T, Snyder JC, Yang X, Rodriguiz RM, Borrelli E, Wetsel WC, Jin J, Roth BL, O'Donnell P, Caron MG. Urs NM, et al. Among authors: pack tf. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8178-E8186. doi: 10.1073/pnas.1614347113. Epub 2016 Dec 1. Proc Natl Acad Sci U S A. 2016. PMID: 27911814 Free PMC article.
A rapid and affordable screening platform for membrane protein trafficking.
Snyder JC, Pack TF, Rochelle LK, Chakraborty SK, Zhang M, Eaton AW, Bai Y, Ernst LA, Barak LS, Waggoner AS, Caron MG. Snyder JC, et al. Among authors: pack tf. BMC Biol. 2015 Dec 17;13:107. doi: 10.1186/s12915-015-0216-3. BMC Biol. 2015. PMID: 26678094 Free PMC article.
Noncanonical scaffolding of Gαi and β-arrestin by G protein-coupled receptors.
Smith JS, Pack TF, Inoue A, Lee C, Zheng K, Choi I, Eiger DS, Warman A, Xiong X, Ma Z, Viswanathan G, Levitan IM, Rochelle LK, Staus DP, Snyder JC, Kahsai AW, Caron MG, Rajagopal S. Smith JS, et al. Among authors: pack tf. Science. 2021 Mar 12;371(6534):eaay1833. doi: 10.1126/science.aay1833. Epub 2021 Jan 21. Science. 2021. PMID: 33479120 Free PMC article.
16 results