Palde PB - Search Results

1

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.

Ryan K, Bolaňos B, Smith M, Palde PB, Cuenca PD, VanArsdale TL, Niessen S, Zhang L, Behenna D, Ornelas MA, Tran KT, Kaiser S, Lum L, Stewart A, Gajiwala KS. Ryan K, et al. Among authors: palde pb. J Biol Chem. 2021 Jan-Jun;296:100251. doi: 10.1074/jbc.RA120.016573. Epub 2021 Jan 9. J Biol Chem. 2021. PMID: 33361107 Free PMC article.

2

[No title available]

[No authors listed] [No authors listed] PMID: 33428942

3

Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.

Kung PP, Bingham P, Burke BJ, Chen Q, Cheng X, Deng YL, Dou D, Feng J, Gallego GM, Gehring MR, Grant SK, Greasley S, Harris AR, Maegley KA, Meier J, Meng X, Montano JL, Morgan BA, Naughton BS, Palde PB, Paul TA, Richardson P, Sakata S, Shaginian A, Sonnenburg WK, Subramanyam C, Timofeevski S, Wan J, Yan W, Stewart AE. Kung PP, et al. Among authors: palde pb. ACS Med Chem Lett. 2020 Apr 10;11(6):1175-1184. doi: 10.1021/acsmedchemlett.0c00029. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32550998 Free PMC article.

4

SAM-Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance.

Jensen-Pergakes K, Tatlock J, Maegley KA, McAlpine IJ, McTigue M, Xie T, Dillon CP, Wang Y, Yamazaki S, Spiegel N, Shi M, Nemeth A, Miller N, Hendrickson E, Lam H, Sherrill J, Chung CY, McMillan EA, Bryant SK, Palde P, Braganza J, Brooun A, Deng YL, Goshtasbi V, Kephart SE, Kumpf RA, Liu W, Patman RL, Rui E, Scales S, Tran-Dube M, Wang F, Wythes M, Paul TA. Jensen-Pergakes K, et al. Mol Cancer Ther. 2022 Jan;21(1):3-15. doi: 10.1158/1535-7163.MCT-21-0620. Epub 2021 Nov 4. Mol Cancer Ther. 2022. PMID: 34737197

5

First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosis.

Palde PB, Bhaskar A, Pedró Rosa LE, Madoux F, Chase P, Gupta V, Spicer T, Scampavia L, Singh A, Carroll KS. Palde PB, et al. ACS Chem Biol. 2016 Jan 15;11(1):172-84. doi: 10.1021/acschembio.5b00517. Epub 2015 Nov 11. ACS Chem Biol. 2016. PMID: 26524379 Free PMC article.

6

Strategies for recognition of stem-loop RNA structures by synthetic ligands: application to the HIV-1 frameshift stimulatory sequence.

Palde PB, Ofori LO, Gareiss PC, Lerea J, Miller BL. Palde PB, et al. J Med Chem. 2010 Aug 26;53(16):6018-27. doi: 10.1021/jm100231t. J Med Chem. 2010. PMID: 20672840 Free PMC article.

7

Functional Site Discovery in a Sulfur Metabolism Enzyme by Using Directed Evolution.

Paritala H, Palde PB, Carroll KS. Paritala H, et al. Among authors: palde pb. Chembiochem. 2016 Oct 4;17(19):1873-1878. doi: 10.1002/cbic.201600264. Epub 2016 Aug 12. Chembiochem. 2016. PMID: 27411165 Free PMC article.

8

A universal entropy-driven mechanism for thioredoxin-target recognition.

Palde PB, Carroll KS. Palde PB, et al. Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):7960-5. doi: 10.1073/pnas.1504376112. Epub 2015 Jun 15. Proc Natl Acad Sci U S A. 2015. PMID: 26080424 Free PMC article.

9

Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase.

Truong TH, Ung PM, Palde PB, Paulsen CE, Schlessinger A, Carroll KS. Truong TH, et al. Among authors: palde pb. Cell Chem Biol. 2016 Jul 21;23(7):837-848. doi: 10.1016/j.chembiol.2016.05.017. Epub 2016 Jul 14. Cell Chem Biol. 2016. PMID: 27427230 Free PMC article.

10

Selective recognition of alkyl pyranosides in protic and aprotic solvents.

Palde PB, Gareiss PC, Miller BL. Palde PB, et al. J Am Chem Soc. 2008 Jul 23;130(29):9566-73. doi: 10.1021/ja802229f. Epub 2008 Jun 25. J Am Chem Soc. 2008. PMID: 18576640

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