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Targeted deletion of all isoforms of the trkC gene suggests the use of alternate receptors by its ligand neurotrophin-3 in neuronal development and implicates trkC in normal cardiogenesis.
Tessarollo L, Tsoulfas P, Donovan MJ, Palko ME, Blair-Flynn J, Hempstead BL, Parada LF. Tessarollo L, et al. Among authors: palko me. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14776-81. doi: 10.1073/pnas.94.26.14776. Proc Natl Acad Sci U S A. 1997. PMID: 9405689 Free PMC article.
Dissection of NT3 functions in vivo by gene replacement strategy.
Coppola V, Kucera J, Palko ME, Martinez-De Velasco J, Lyons WE, Fritzsch B, Tessarollo L. Coppola V, et al. Among authors: palko me. Development. 2001 Nov;128(21):4315-27. doi: 10.1242/dev.128.21.4315. Development. 2001. PMID: 11684666
Gene targeting in mouse embryonic stem cells.
Tessarollo L, Palko ME, Akagi K, Coppola V. Tessarollo L, et al. Among authors: palko me. Methods Mol Biol. 2009;530:141-64. doi: 10.1007/978-1-59745-471-1_8. Methods Mol Biol. 2009. PMID: 19266325 Free PMC article.
TrkA in vivo function is negatively regulated by ubiquitination.
Kiris E, Wang T, Yanpallewar S, Dorsey SG, Becker J, Bavari S, Palko ME, Coppola V, Tessarollo L. Kiris E, et al. Among authors: palko me. J Neurosci. 2014 Mar 12;34(11):4090-8. doi: 10.1523/JNEUROSCI.4294-13.2014. J Neurosci. 2014. PMID: 24623787 Free PMC article.
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