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Mechanobiology of YAP and TAZ in physiology and disease.
Panciera T, Azzolin L, Cordenonsi M, Piccolo S. Panciera T, et al. Nat Rev Mol Cell Biol. 2017 Dec;18(12):758-770. doi: 10.1038/nrm.2017.87. Epub 2017 Sep 27. Nat Rev Mol Cell Biol. 2017. PMID: 28951564 Free PMC article. Review.
De Novo Generation of Somatic Stem Cells by YAP/TAZ.
Panciera T, Azzolin L, Di Biagio D, Totaro A, Cordenonsi M, Piccolo S. Panciera T, et al. J Vis Exp. 2018 May 7;(135):57462. doi: 10.3791/57462. J Vis Exp. 2018. PMID: 29782008 Free PMC article.
YAP/TAZ upstream signals and downstream responses.
Totaro A, Panciera T, Piccolo S. Totaro A, et al. Among authors: panciera t. Nat Cell Biol. 2018 Aug;20(8):888-899. doi: 10.1038/s41556-018-0142-z. Epub 2018 Jul 26. Nat Cell Biol. 2018. PMID: 30050119 Free PMC article. Review.
The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ.
Chang L, Azzolin L, Di Biagio D, Zanconato F, Battilana G, Lucon Xiccato R, Aragona M, Giulitti S, Panciera T, Gandin A, Sigismondo G, Krijgsveld J, Fassan M, Brusatin G, Cordenonsi M, Piccolo S. Chang L, et al. Among authors: panciera t. Nature. 2018 Nov;563(7730):265-269. doi: 10.1038/s41586-018-0658-1. Epub 2018 Oct 31. Nature. 2018. PMID: 30401838 Free PMC article.
Cell phenotypic plasticity requires autophagic flux driven by YAP/TAZ mechanotransduction.
Totaro A, Zhuang Q, Panciera T, Battilana G, Azzolin L, Brumana G, Gandin A, Brusatin G, Cordenonsi M, Piccolo S. Totaro A, et al. Among authors: panciera t. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17848-17857. doi: 10.1073/pnas.1908228116. Epub 2019 Aug 15. Proc Natl Acad Sci U S A. 2019. PMID: 31416916 Free PMC article.
Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties.
Panciera T, Citron A, Di Biagio D, Battilana G, Gandin A, Giulitti S, Forcato M, Bicciato S, Panzetta V, Fusco S, Azzolin L, Totaro A, Dei Tos AP, Fassan M, Vindigni V, Bassetto F, Rosato A, Brusatin G, Cordenonsi M, Piccolo S. Panciera T, et al. Nat Mater. 2020 Jul;19(7):797-806. doi: 10.1038/s41563-020-0615-x. Epub 2020 Feb 17. Nat Mater. 2020. PMID: 32066931 Free PMC article.
22 results