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Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair.
Gupta A, Yang Q, Pandita RK, Hunt CR, Xiang T, Misri S, Zeng S, Pagan J, Jeffery J, Puc J, Kumar R, Feng Z, Powell SN, Bhat A, Yaguchi T, Wadhwa R, Kaul SC, Parsons R, Khanna KK, Pandita TK. Gupta A, et al. Among authors: pandita tk, pandita rk. Cell Cycle. 2009 Jul 15;8(14):2198-210. doi: 10.4161/cc.8.14.8947. Epub 2009 Jul 7. Cell Cycle. 2009. PMID: 19502790 Free article.
Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair.
Pandita RK, Sharma GG, Laszlo A, Hopkins KM, Davey S, Chakhparonian M, Gupta A, Wellinger RJ, Zhang J, Powell SN, Roti Roti JL, Lieberman HB, Pandita TK. Pandita RK, et al. Among authors: pandita tk. Mol Cell Biol. 2006 Mar;26(5):1850-64. doi: 10.1128/MCB.26.5.1850-1864.2006. Mol Cell Biol. 2006. PMID: 16479004 Free PMC article.
Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status.
Hunt CR, Pandita RK, Laszlo A, Higashikubo R, Agarwal M, Kitamura T, Gupta A, Rief N, Horikoshi N, Baskaran R, Lee JH, Löbrich M, Paull TT, Roti Roti JL, Pandita TK. Hunt CR, et al. Among authors: pandita tk, pandita rk. Cancer Res. 2007 Apr 1;67(7):3010-7. doi: 10.1158/0008-5472.CAN-06-4328. Cancer Res. 2007. PMID: 17409407
MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice.
Gupta A, Hunt CR, Hegde ML, Chakraborty S, Chakraborty S, Udayakumar D, Horikoshi N, Singh M, Ramnarain DB, Hittelman WN, Namjoshi S, Asaithamby A, Hazra TK, Ludwig T, Pandita RK, Tyler JK, Pandita TK. Gupta A, et al. Among authors: pandita tk, pandita rk. Cell Rep. 2014 Jul 10;8(1):177-89. doi: 10.1016/j.celrep.2014.05.044. Epub 2014 Jun 19. Cell Rep. 2014. PMID: 24953651 Free PMC article.
Role of Histone Methylation in Maintenance of Genome Integrity.
Mushtaq A, Mir US, Hunt CR, Pandita S, Tantray WW, Bhat A, Pandita RK, Altaf M, Pandita TK. Mushtaq A, et al. Among authors: pandita rk. Genes (Basel). 2021 Jun 29;12(7):1000. doi: 10.3390/genes12071000. Genes (Basel). 2021. PMID: 34209979 Free PMC article. Review.
Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation.
Sharma GG, Hwang KK, Pandita RK, Gupta A, Dhar S, Parenteau J, Agarwal M, Worman HJ, Wellinger RJ, Pandita TK. Sharma GG, et al. Among authors: pandita tk, pandita rk. Mol Cell Biol. 2003 Nov;23(22):8363-76. doi: 10.1128/MCB.23.22.8363-8376.2003. Mol Cell Biol. 2003. PMID: 14585993 Free PMC article.
The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis.
Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, Ludwig T, Pandita TK. Gupta A, et al. Among authors: pandita s, pandita tk, pandita rk. Mol Cell Biol. 2008 Jan;28(1):397-409. doi: 10.1128/MCB.01045-07. Epub 2007 Oct 29. Mol Cell Biol. 2008. PMID: 17967868 Free PMC article.
112 results