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Role of Glycosyltransferases Modifying Type B Flagellin of Emerging Hypervirulent Clostridium difficile Lineages and Their Impact on Motility and Biofilm Formation.
Valiente E, Bouché L, Hitchen P, Faulds-Pain A, Songane M, Dawson LF, Donahue E, Stabler RA, Panico M, Morris HR, Bajaj-Elliott M, Logan SM, Dell A, Wren BW. Valiente E, et al. Among authors: panico m. J Biol Chem. 2016 Dec 2;291(49):25450-25461. doi: 10.1074/jbc.M116.749523. Epub 2016 Oct 4. J Biol Chem. 2016. PMID: 27703012 Free PMC article.
We show that the glycosyltransferases 1 and 2 (GT1 and GT2) are responsible for the sequential addition of a GlcNAc and two rhamnoses, respectively, and that GT3 is associated with the incorporation of a novel sulfonated peptidyl-amido sugar moiety whose structure is reported in …
We show that the glycosyltransferases 1 and 2 (GT1 and GT2) are responsible for the sequential addition of a GlcNAc and two rhamnoses, respe …
The Type B Flagellin of Hypervirulent Clostridium difficile Is Modified with Novel Sulfonated Peptidylamido-glycans.
Bouché L, Panico M, Hitchen P, Binet D, Sastre F, Faulds-Pain A, Valiente E, Vinogradov E, Aubry A, Fulton K, Twine S, Logan SM, Wren BW, Dell A, Morris HR. Bouché L, et al. Among authors: panico m. J Biol Chem. 2016 Dec 2;291(49):25439-25449. doi: 10.1074/jbc.M116.749481. Epub 2016 Oct 7. J Biol Chem. 2016. PMID: 27758867 Free PMC article.
266 results