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Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD).
Lagu B, Kluge AF, Tozzo E, Fredenburg R, Bell EL, Goddeeris MM, Dwyer P, Basinski A, Senaiar RS, Jaleel M, Tiwari NK, Panigrahi SK, Krishnamurthy NR, Takahashi T, Patane MA. Lagu B, et al. Among authors: panigrahi sk. ACS Med Chem Lett. 2018 Jul 31;9(9):935-940. doi: 10.1021/acsmedchemlett.8b00287. eCollection 2018 Sep 13. ACS Med Chem Lett. 2018. PMID: 30258544 Free PMC article.
Novel highly selective peroxisome proliferator-activated receptor δ (PPARδ) modulators with pharmacokinetic properties suitable for once-daily oral dosing.
Lagu B, Kluge AF, Fredenburg RA, Tozzo E, Senaiar RS, Jaleel M, Panigrahi SK, Tiwari NK, Krishnamurthy NR, Takahashi T, Patane MA. Lagu B, et al. Among authors: panigrahi sk. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5230-5234. doi: 10.1016/j.bmcl.2017.10.037. Epub 2017 Oct 27. Bioorg Med Chem Lett. 2017. PMID: 29103972
Correction to "Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD)".
Lagu B, Kluge AF, Tozzo E, Fredenburg R, Bell EL, Goddeeris MM, Dwyer P, Basinski A, Senaiar RS, Jaleel M, Tiwari NK, Panigrahi SK, Krishnamurthy NR, Takahashi T, Patane MA. Lagu B, et al. Among authors: panigrahi sk. ACS Med Chem Lett. 2019 Apr 24;10(6):1013. doi: 10.1021/acsmedchemlett.9b00160. eCollection 2019 Jun 13. ACS Med Chem Lett. 2019. PMID: 31223463 Free PMC article.
Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: wild type and mutant (L1196M) active compounds with unique binding mode.
Gummadi VR, Rajagopalan S, Looi CY, Paydar M, Renukappa GA, Ainan BR, Krishnamurthy NR, Panigrahi SK, Mahasweta K, Raghuramachandran S, Rajappa M, Ramanathan A, Lakshminarasimhan A, Ramachandra M, Wong PF, Mustafa MR, Nanduri S, Hosahalli S. Gummadi VR, et al. Among authors: panigrahi sk. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4911-8. doi: 10.1016/j.bmcl.2013.06.071. Epub 2013 Jul 4. Bioorg Med Chem Lett. 2013. PMID: 23880539
X-ray structure of PTP1B in complex with a new PTP1B inhibitor.
Reddy MV, Ghadiyaram C, Panigrahi SK, Krishnamurthy NR, Hosahalli S, Chandrasekharappa AP, Manna D, Badiger SE, Dubey PK, Mangamoori LN. Reddy MV, et al. Among authors: panigrahi sk. Protein Pept Lett. 2014;21(1):90-3. doi: 10.2174/09298665113209990089. Protein Pept Lett. 2014. PMID: 23964742
Discovery of MAP855, an Efficacious and Selective MEK1/2 Inhibitor with an ATP-Competitive Mode of Action.
Poddutoori R, Aardalen K, Aithal K, Barahagar SS, Belliappa C, Bock M, Chelur S, Gerken A, Gopinath S, Gruenenfelder B, Kiffe M, Krishnaswami M, Langowski J, Madapa S, Narayanan K, Pandit C, Panigrahi SK, Perrone M, Potakamuri RK, Ramachandra M, Ramanathan A, Ramos R, Sager E, Samajdar S, Subramanya HS, Thimmasandra DS, Venetsanakos E, Möbitz H. Poddutoori R, et al. Among authors: panigrahi sk. J Med Chem. 2022 Mar 10;65(5):4350-4366. doi: 10.1021/acs.jmedchem.1c02192. Epub 2022 Feb 23. J Med Chem. 2022. PMID: 35195996
Discovery of azetidine based ene-amides as potent bacterial enoyl ACP reductase (FabI) inhibitors.
Takhi M, Sreenivas K, Reddy CK, Munikumar M, Praveena K, Sudheer P, Rao BN, Ramakanth G, Sivaranjani J, Mulik S, Reddy YR, Narasimha Rao K, Pallavi R, Lakshminarasimhan A, Panigrahi SK, Antony T, Abdullah I, Lee YK, Ramachandra M, Yusof R, Rahman NA, Subramanya H. Takhi M, et al. Among authors: panigrahi sk. Eur J Med Chem. 2014 Sep 12;84:382-94. doi: 10.1016/j.ejmech.2014.07.036. Epub 2014 Jul 11. Eur J Med Chem. 2014. PMID: 25036796
89 results