Pantze M - Search Results

1

Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer.

Calvert H, Twelves C, Ranson M, Plummer R, Fettner S, Pantze M, Ling J, Hamilton M, Lum BL, Rakhit A. Calvert H, et al. Among authors: pantze m. Anticancer Drugs. 2014 Aug;25(7):832-40. doi: 10.1097/CAD.0000000000000099. Anticancer Drugs. 2014. PMID: 24637575 Clinical Trial.

2

Metabolism and excretion of erlotinib, a small molecule inhibitor of epidermal growth factor receptor tyrosine kinase, in healthy male volunteers.

Ling J, Johnson KA, Miao Z, Rakhit A, Pantze MP, Hamilton M, Lum BL, Prakash C. Ling J, et al. Among authors: pantze mp. Drug Metab Dispos. 2006 Mar;34(3):420-6. doi: 10.1124/dmd.105.007765. Epub 2005 Dec 28. Drug Metab Dispos. 2006. PMID: 16381666

3

The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition.

Rakhit A, Pantze MP, Fettner S, Jones HM, Charoin JE, Riek M, Lum BL, Hamilton M. Rakhit A, et al. Among authors: pantze mp. Eur J Clin Pharmacol. 2008 Jan;64(1):31-41. doi: 10.1007/s00228-007-0396-z. Epub 2007 Nov 14. Eur J Clin Pharmacol. 2008. PMID: 18000659 Clinical Trial.

4

Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: in vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat.

Funk C, Ponelle C, Scheuermann G, Pantze M. Funk C, et al. Among authors: pantze m. Mol Pharmacol. 2001 Mar;59(3):627-35. Mol Pharmacol. 2001. PMID: 11179459

5

The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions.

Fattinger K, Funk C, Pantze M, Weber C, Reichen J, Stieger B, Meier PJ. Fattinger K, et al. Among authors: pantze m. Clin Pharmacol Ther. 2001 Apr;69(4):223-31. doi: 10.1067/mcp.2001.114667. Clin Pharmacol Ther. 2001. PMID: 11309550

6

Pharmacokinetics and metabolism of the dipeptidyl peptidase IV inhibitor carmegliptin in rats, dogs, and monkeys.

Kuhlmann O, Paehler A, Weick I, Funk C, Pantze M, Zell M, Timm U. Kuhlmann O, et al. Among authors: pantze m. Xenobiotica. 2010 Dec;40(12):840-52. doi: 10.3109/00498254.2010.519406. Epub 2010 Sep 24. Xenobiotica. 2010. PMID: 20868265

7

Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration.

Zheng Y, Tesar DB, Benincosa L, Birnböck H, Boswell CA, Bumbaca D, Cowan KJ, Danilenko DM, Daugherty AL, Fielder PJ, Grimm HP, Joshi A, Justies N, Kolaitis G, Lewin-Koh N, Li J, McVay S, O'Mahony J, Otteneder M, Pantze M, Putnam WS, Qiu ZJ, Ruppel J, Singer T, Stauch O, Theil FP, Visich J, Yang J, Ying Y, Khawli LA, Richter WF. Zheng Y, et al. Among authors: pantze m. MAbs. 2012 Mar-Apr;4(2):243-55. doi: 10.4161/mabs.4.2.19387. Epub 2012 Mar 1. MAbs. 2012. PMID: 22453096 Free PMC article.

8

Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile salt export pump (Bsep) by troglitazone and troglitazone sulfate.

Funk C, Pantze M, Jehle L, Ponelle C, Scheuermann G, Lazendic M, Gasser R. Funk C, et al. Among authors: pantze m. Toxicology. 2001 Oct 5;167(1):83-98. doi: 10.1016/s0300-483x(01)00460-7. Toxicology. 2001. PMID: 11557132

9

Anti-inflammatory properties of docosahexaenoic and eicosapentaenoic acids in phorbol-ester-induced mouse ear inflammation.

Raederstorff D, Pantze M, Bachmann H, Moser U. Raederstorff D, et al. Among authors: pantze m. Int Arch Allergy Immunol. 1996 Nov;111(3):284-90. doi: 10.1159/000237379. Int Arch Allergy Immunol. 1996. PMID: 8917124

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