Pao W - Search Results

1

Evolutionary modeling of combination treatment strategies to overcome resistance to tyrosine kinase inhibitors in non-small cell lung cancer.

Mumenthaler SM, Foo J, Leder K, Choi NC, Agus DB, Pao W, Mallick P, Michor F. Mumenthaler SM, et al. Among authors: pao w. Mol Pharm. 2011 Dec 5;8(6):2069-79. doi: 10.1021/mp200270v. Epub 2011 Oct 25. Mol Pharm. 2011. PMID: 21995722 Free PMC article.

2

Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling.

Chmielecki J, Foo J, Oxnard GR, Hutchinson K, Ohashi K, Somwar R, Wang L, Amato KR, Arcila M, Sos ML, Socci ND, Viale A, de Stanchina E, Ginsberg MS, Thomas RK, Kris MG, Inoue A, Ladanyi M, Miller VA, Michor F, Pao W. Chmielecki J, et al. Among authors: pao w. Sci Transl Med. 2011 Jul 6;3(90):90ra59. doi: 10.1126/scitranslmed.3002356. Sci Transl Med. 2011. PMID: 21734175 Free PMC article.

3

Effects of pharmacokinetic processes and varied dosing schedules on the dynamics of acquired resistance to erlotinib in EGFR-mutant lung cancer.

Foo J, Chmielecki J, Pao W, Michor F. Foo J, et al. Among authors: pao w. J Thorac Oncol. 2012 Oct;7(10):1583-93. doi: 10.1097/JTO.0b013e31826146ee. J Thorac Oncol. 2012. PMID: 22982659 Free PMC article.

4

The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells.

Mumenthaler SM, Foo J, Choi NC, Heise N, Leder K, Agus DB, Pao W, Michor F, Mallick P. Mumenthaler SM, et al. Among authors: pao w. Cancer Inform. 2015 Jul 15;14(Suppl 4):19-31. doi: 10.4137/CIN.S19338. eCollection 2015. Cancer Inform. 2015. PMID: 26244007 Free PMC article.

5

Dose-Dependent Mutation Rates Determine Optimum Erlotinib Dosing Strategies for EGFR Mutant Non-Small Cell Lung Cancer Patients.

Liu LL, Li F, Pao W, Michor F. Liu LL, et al. Among authors: pao w. PLoS One. 2015 Nov 4;10(11):e0141665. doi: 10.1371/journal.pone.0141665. eCollection 2015. PLoS One. 2015. PMID: 26536620 Free PMC article.

6

Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease.

Ohashi K, Maruvka YE, Michor F, Pao W. Ohashi K, et al. Among authors: pao w. J Clin Oncol. 2013 Mar 10;31(8):1070-80. doi: 10.1200/JCO.2012.43.3912. Epub 2013 Feb 11. J Clin Oncol. 2013. PMID: 23401451 Free PMC article. Review.

7

Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistance.

Jia P, Jin H, Meador CB, Xia J, Ohashi K, Liu L, Pirazzoli V, Dahlman KB, Politi K, Michor F, Zhao Z, Pao W. Jia P, et al. Among authors: pao w. Genome Res. 2013 Sep;23(9):1434-45. doi: 10.1101/gr.152322.112. Epub 2013 Jun 3. Genome Res. 2013. PMID: 23733853 Free PMC article.

8

Phase 1 study of twice weekly pulse dose and daily low-dose erlotinib as initial treatment for patients with EGFR-mutant lung cancers.

Yu HA, Sima C, Feldman D, Liu LL, Vaitheesvaran B, Cross J, Rudin CM, Kris MG, Pao W, Michor F, Riely GJ. Yu HA, et al. Among authors: pao w. Ann Oncol. 2017 Feb 1;28(2):278-284. doi: 10.1093/annonc/mdw556. Ann Oncol. 2017. PMID: 28073786 Free PMC article. Clinical Trial.

9

Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer.

Jackman D, Pao W, Riely GJ, Engelman JA, Kris MG, Jänne PA, Lynch T, Johnson BE, Miller VA. Jackman D, et al. Among authors: pao w. J Clin Oncol. 2010 Jan 10;28(2):357-60. doi: 10.1200/JCO.2009.24.7049. Epub 2009 Nov 30. J Clin Oncol. 2010. PMID: 19949011 Free PMC article.

10

EPHA2 Blockade Overcomes Acquired Resistance to EGFR Kinase Inhibitors in Lung Cancer.

Amato KR, Wang S, Tan L, Hastings AK, Song W, Lovly CM, Meador CB, Ye F, Lu P, Balko JM, Colvin DC, Cates JM, Pao W, Gray NS, Chen J. Amato KR, et al. Among authors: pao w. Cancer Res. 2016 Jan 15;76(2):305-18. doi: 10.1158/0008-5472.CAN-15-0717. Epub 2016 Jan 7. Cancer Res. 2016. PMID: 26744526 Free PMC article.

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