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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2004 1
2005 2
2006 3
2010 3
2011 2
2012 2
2013 3
2014 4
2015 2
2016 4
2017 3
2018 2
2019 2
2020 1
2021 3
2022 3
2023 2
2024 1

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38 results

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Page 1
VIRMA facilitates intrahepatic cholangiocarcinoma progression through epigenetic augmentation of TMED2 and PARD3B mRNA stabilization.
Xu H, Lin X, Li Z, He X, Li Y, Qiu L, Lu L, Liu B, Zhan M, He K. Xu H, et al. J Gastroenterol. 2023 Sep;58(9):925-944. doi: 10.1007/s00535-023-02015-5. Epub 2023 Jun 30. J Gastroenterol. 2023. PMID: 37391589
Mechanistically, multi-omics analysis using ICC cells demonstrated that TMED2 and PARD3B were the direct downstream target of VIRMA. The methylated TMED2 and PARD3B transcripts were directly recognized by HuR, which exerted stabilizing effects on its bound RNA. VIRM …
Mechanistically, multi-omics analysis using ICC cells demonstrated that TMED2 and PARD3B were the direct downstream target of VIRMA. …
Contribution of the Testosterone Androgen Receptor-PARD3B Signaling Axis to Tumorigenesis and Malignance of Glioblastoma Multiforme through Stimulating Cell Proliferation and Colony Formation.
Yang JD, Chen JT, Liu SH, Chen RM. Yang JD, et al. J Clin Med. 2022 Aug 17;11(16):4818. doi: 10.3390/jcm11164818. J Clin Med. 2022. PMID: 36013056 Free PMC article.
Interestingly, a highly positive correlation between AR and PARD3B gene expressions in human GBM was identified. The results of a bioinformatics search further showed that there were five AR-specific DNA-binding elements predicted in the 5' promoter of the PARD3B ge …
Interestingly, a highly positive correlation between AR and PARD3B gene expressions in human GBM was identified. The results of a bio …
Par-3 family proteins in cell polarity & adhesion.
Thompson BJ. Thompson BJ. FEBS J. 2022 Feb;289(3):596-613. doi: 10.1111/febs.15754. Epub 2021 Mar 3. FEBS J. 2022. PMID: 33565714 Free PMC article. Review.
The evolution of Par-3 family proteins into distinct apical PARD3 and junctional PARD3B orthologs coincides with the emergence of stratified squamous epithelia in vertebrates, where PARD3B, but not PARD3, is strongly expressed in basal layer stem cells - which lack …
The evolution of Par-3 family proteins into distinct apical PARD3 and junctional PARD3B orthologs coincides with the emergence of str …
Genome-wide association study implicates PARD3B-based AIDS restriction.
Troyer JL, Nelson GW, Lautenberger JA, Chinn L, McIntosh C, Johnson RC, Sezgin E, Kessing B, Malasky M, Hendrickson SL, Li G, Pontius J, Tang M, An P, Winkler CA, Limou S, Le Clerc S, Delaneau O, Zagury JF, Schuitemaker H, van Manen D, Bream JH, Gomperts ED, Buchbinder S, Goedert JJ, Kirk GD, O'Brien SJ. Troyer JL, et al. J Infect Dis. 2011 May 15;203(10):1491-502. doi: 10.1093/infdis/jir046. J Infect Dis. 2011. PMID: 21502085 Free PMC article.
Nine of the top-ranked SNPs define a PARD3B haplotype that also displays significant association with progression to AIDS (hazard ratio, 0.3; P = 3.220 10(-8)). One of these SNPs, rs10185378, is a predicted exonic splicing enhancer; significant alteration in the expression …
Nine of the top-ranked SNPs define a PARD3B haplotype that also displays significant association with progression to AIDS (hazard rat …
Gene fusions during the early evolution of mesothelioma correlate with impaired DNA repair and Hippo pathways.
Jama M, Zhang M, Poile C, Nakas A, Sharkey A, Dzialo J, Dawson A, Kutywayo K, Fennell DA, Hollox EJ. Jama M, et al. Genes Chromosomes Cancer. 2024 Jan;63(1):e23189. doi: 10.1002/gcc.23189. Epub 2023 Jul 8. Genes Chromosomes Cancer. 2024. PMID: 37421230
Fusions involved known tumor suppressors BAP1, MTAP, and LRP1B, and a clonal oncogenic fusion involving CACNA1D-ERC2, PARD3B-NT5DC2, and STAB2-NT5DC2 fusions were also identified as clonal fusions. ...
Fusions involved known tumor suppressors BAP1, MTAP, and LRP1B, and a clonal oncogenic fusion involving CACNA1D-ERC2, PARD3B-NT5DC2, …
A proximity proteomics screen in three-dimensional spheroid cultures identifies novel regulators of lumen formation.
Wang LT, Proulx MÈ, Kim AD, Lelarge V, McCaffrey L. Wang LT, et al. Sci Rep. 2021 Nov 23;11(1):22807. doi: 10.1038/s41598-021-02178-2. Sci Rep. 2021. PMID: 34815476 Free PMC article.
Using this approach, we identified several known and unknown proteins proximally associated with PAR6B, an apical protein involved in lumen formation. Functional analyses of candidates identified PARD3B (a homolog of PARD3), RALB, and HRNR as regulators of lumen formation. …
Using this approach, we identified several known and unknown proteins proximally associated with PAR6B, an apical protein involved in lumen …
HIV types, groups, subtypes and recombinant forms: errors in replication, selection pressure and quasispecies.
Eberle J, Gürtler L. Eberle J, et al. Intervirology. 2012;55(2):79-83. doi: 10.1159/000331993. Epub 2012 Jan 24. Intervirology. 2012. PMID: 22286874 Free article. Review.
Human genetic factors associated with a better clinical outcome are proteins such as APOBEC, langerin, tetherin and chemokine receptor 5 (CCR5) and HLA B27, B57, DRB1*1303, KIR and PARD3B....
Human genetic factors associated with a better clinical outcome are proteins such as APOBEC, langerin, tetherin and chemokine receptor 5 (CC …
Hydrochlorothiazide-induced hyperuricaemia in the pharmacogenomic evaluation of antihypertensive responses study.
Vandell AG, McDonough CW, Gong Y, Langaee TY, Lucas AM, Chapman AB, Gums JG, Beitelshees AL, Bailey KR, Johnson RJ, Boerwinkle E, Turner ST, Cooper-DeHoff RM, Johnson JA. Vandell AG, et al. J Intern Med. 2014 Nov;276(5):486-97. doi: 10.1111/joim.12215. Epub 2014 Feb 28. J Intern Med. 2014. PMID: 24612202 Free PMC article.
RESULTS: Five unique gene regions were identified in African Americans (LUC7L2, ANKRD17/COX18, FTO, PADI4 and PARD3B), and one region was identified in Caucasians (GRIN3A). Increases in UA of up to 1.8 mg dL(-1) were observed following HCTZ therapy in individuals homozygou …
RESULTS: Five unique gene regions were identified in African Americans (LUC7L2, ANKRD17/COX18, FTO, PADI4 and PARD3B), and one region …
Identification of Novel Genetic Variants and Comorbidities Associated With ICD-10-Based Diagnosis of Hypertrophic Cardiomyopathy Using the UK Biobank Cohort.
Gyftopoulos A, Chen YJ, Wang L, Williams CH, Chun YW, O'Connell JR, Perry JA, Hong CC. Gyftopoulos A, et al. Front Genet. 2022 May 24;13:866042. doi: 10.3389/fgene.2022.866042. eCollection 2022. Front Genet. 2022. PMID: 35685441 Free PMC article.

We identified two novel, non-sarcomeric genetic variants in KMT2C rs78630626, and PARD3B rs188937806 that were associated with ICD-10 codes for HCM with genome-wide significance (p < 5 x 10(-8)). ...This UK Biobank database-based GWAS identified common variants in KMT2C

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We identified two novel, non-sarcomeric genetic variants in KMT2C rs78630626, and PARD3B rs188937806 that were associated with ICD-10 …
38 results