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Secretion of Acid Sphingomyelinase and Ceramide by Endothelial Cells Contributes to Radiation-Induced Intestinal Toxicity.
Leonetti D, Estéphan H, Ripoche N, Dubois N, Aguesse A, Gouard S, Brossard L, Chiavassa S, Corre I, Pecqueur C, Neunlist M, Hadchity E, Gaugler MH, Mahé MM, Paris F. Leonetti D, et al. Among authors: paris f. Cancer Res. 2020 Jun 15;80(12):2651-2662. doi: 10.1158/0008-5472.CAN-19-1527. Epub 2020 Apr 14. Cancer Res. 2020. PMID: 32291318
Plasma ceramide, a real-time predictive marker of pulmonary and hepatic metastases response to stereotactic body radiation therapy combined with irinotecan.
Dubois N, Rio E, Ripoche N, Ferchaud-Roucher V, Gaugler MH, Campion L, Krempf M, Carrie C, Mahé M, Mirabel X, Paris F. Dubois N, et al. Among authors: paris f. Radiother Oncol. 2016 May;119(2):229-35. doi: 10.1016/j.radonc.2016.03.014. Epub 2016 Apr 21. Radiother Oncol. 2016. PMID: 27113798 Free article. Clinical Trial.
Oxidative stress disassembles the p38/NPM/PP2A complex, which leads to modulation of nucleophosmin-mediated signaling to DNA damage response.
Guillonneau M, Paris F, Dutoit S, Estephan H, Bénéteau E, Huot J, Corre I. Guillonneau M, et al. Among authors: paris f. FASEB J. 2016 Aug;30(8):2899-914. doi: 10.1096/fj.201500194R. Epub 2016 May 3. FASEB J. 2016. PMID: 27142525
Overall, these results suggest that the p38/NPM/PP2A complex acts as a dynamic sensor, allowing endothelial cells to react rapidly to acute oxidative stress.-Guillonneau, M., Paris, F., Dutoit, S., Estephan, H., Beneteau, E., Huot, J., Corre, I. ...
Overall, these results suggest that the p38/NPM/PP2A complex acts as a dynamic sensor, allowing endothelial cells to react rapidly to acute …
450 results