Parkinson GN - Search Results

1

Selectivity in ligand recognition of G-quadruplex loops.

Campbell NH, Patel M, Tofa AB, Ghosh R, Parkinson GN, Neidle S. Campbell NH, et al. Among authors: parkinson gn. Biochemistry. 2009 Mar 3;48(8):1675-80. doi: 10.1021/bi802233v. Biochemistry. 2009. PMID: 19173611

2

A new crystal form for the dodecamer C-G-C-G-A-A-T-T-C-G-C-G: symmetry effects on sequence-dependent DNA structure.

Johansson E, Parkinson G, Neidle S. Johansson E, et al. J Mol Biol. 2000 Jul 14;300(3):551-61. doi: 10.1006/jmbi.2000.3907. J Mol Biol. 2000. PMID: 10884351

3

Crystal structure of FMN-dependent nitroreductase from Escherichia coli B: a prodrug-activating enzyme.

Parkinson GN, Skelly JV, Neidle S. Parkinson GN, et al. J Med Chem. 2000 Oct 5;43(20):3624-31. doi: 10.1021/jm000159m. J Med Chem. 2000. PMID: 11020276

4

A new class of symmetric bisbenzimidazole-based DNA minor groove-binding agents showing antitumor activity.

Mann J, Baron A, Opoku-Boahen Y, Johansson E, Parkinson G, Kelland LR, Neidle S. Mann J, et al. J Med Chem. 2001 Jan 18;44(2):138-44. doi: 10.1021/jm000297b. J Med Chem. 2001. PMID: 11170623

5

Crystal structure of parallel quadruplexes from human telomeric DNA.

Parkinson GN, Lee MP, Neidle S. Parkinson GN, et al. Nature. 2002 Jun 20;417(6891):876-80. doi: 10.1038/nature755. Epub 2002 May 26. Nature. 2002. PMID: 12050675

6

Crystal structure of the potassium form of an Oxytricha nova G-quadruplex.

Haider S, Parkinson GN, Neidle S. Haider S, et al. Among authors: parkinson gn. J Mol Biol. 2002 Jul 5;320(2):189-200. doi: 10.1016/S0022-2836(02)00428-X. J Mol Biol. 2002. PMID: 12079378

7

Telomere maintenance as a target for anticancer drug discovery.

Neidle S, Parkinson G. Neidle S, et al. Nat Rev Drug Discov. 2002 May;1(5):383-93. doi: 10.1038/nrd793. Nat Rev Drug Discov. 2002. PMID: 12120414 Review.

8

Structure of a G-quadruplex-ligand complex.

Haider SM, Parkinson GN, Neidle S. Haider SM, et al. Among authors: parkinson gn. J Mol Biol. 2003 Feb 7;326(1):117-25. doi: 10.1016/s0022-2836(02)01354-2. J Mol Biol. 2003. PMID: 12547195

9

The structure of telomeric DNA.

Neidle S, Parkinson GN. Neidle S, et al. Among authors: parkinson gn. Curr Opin Struct Biol. 2003 Jun;13(3):275-83. doi: 10.1016/s0959-440x(03)00072-1. Curr Opin Struct Biol. 2003. PMID: 12831878 Review.

10

Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form.

Johansson E, Parkinson GN, Denny WA, Neidle S. Johansson E, et al. Among authors: parkinson gn. J Med Chem. 2003 Sep 11;46(19):4009-20. doi: 10.1021/jm030843b. J Med Chem. 2003. PMID: 12954054

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