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The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells.
Spinello I, Saulle E, Quaranta MT, Pasquini L, Pelosi E, Castelli G, Ottone T, Voso MT, Testa U, Labbaye C. Spinello I, et al. Among authors: pasquini l. Haematologica. 2019 May;104(5):973-985. doi: 10.3324/haematol.2018.199661. Epub 2018 Nov 22. Haematologica. 2019. PMID: 30467201 Free PMC article.
Impaired myelopoiesis in mice devoid of interferon regulatory factor 1.
Testa U, Stellacci E, Pelosi E, Sestili P, Venditti M, Orsatti R, Fragale A, Petrucci E, Pasquini L, Belardelli F, Gabriele L, Battistini A. Testa U, et al. Among authors: pasquini l. Leukemia. 2004 Nov;18(11):1864-71. doi: 10.1038/sj.leu.2403472. Leukemia. 2004. PMID: 15385939
Circulating haemopoietic and endothelial progenitor cells are decreased in COPD.
Palange P, Testa U, Huertas A, Calabrò L, Antonucci R, Petrucci E, Pelosi E, Pasquini L, Satta A, Morici G, Vignola MA, Bonsignore MR. Palange P, et al. Among authors: pasquini l. Eur Respir J. 2006 Mar;27(3):529-41. doi: 10.1183/09031936.06.00120604. Eur Respir J. 2006. PMID: 16507853 Free article.
Podocalyxin is expressed in normal and leukemic monocytes.
Riccioni R, Calzolari A, Biffoni M, Senese M, Riti V, Petrucci E, Pasquini L, Cedrone M, Lo-Coco F, Diverio D, Foà R, Peschle C, Testa U. Riccioni R, et al. Among authors: pasquini l. Blood Cells Mol Dis. 2006 Nov-Dec;37(3):218-25. doi: 10.1016/j.bcmd.2006.09.001. Epub 2006 Oct 23. Blood Cells Mol Dis. 2006. PMID: 17059890 Clinical Trial.
Proteasome inhibitors sensitize ovarian cancer cells to TRAIL induced apoptosis.
Saulle E, Petronelli A, Pasquini L, Petrucci E, Mariani G, Biffoni M, Ferretti G, Scambia G, Benedetti-Panici P, Cognetti F, Humphreys R, Peschle C, Testa U. Saulle E, et al. Among authors: pasquini l. Apoptosis. 2007 Apr;12(4):635-55. doi: 10.1007/s10495-006-0025-9. Apoptosis. 2007. PMID: 17252198
A small molecule Smac mimic potentiates TRAIL-mediated cell death of ovarian cancer cells.
Petrucci E, Pasquini L, Petronelli A, Saulle E, Mariani G, Riccioni R, Biffoni M, Ferretti G, Benedetti-Panici P, Cognetti F, Scambia G, Humphreys R, Peschle C, Testa U. Petrucci E, et al. Among authors: pasquini l. Gynecol Oncol. 2007 May;105(2):481-92. doi: 10.1016/j.ygyno.2007.01.011. Epub 2007 Feb 9. Gynecol Oncol. 2007. PMID: 17292950
A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis.
Labbaye C, Spinello I, Quaranta MT, Pelosi E, Pasquini L, Petrucci E, Biffoni M, Nuzzolo ER, Billi M, Foà R, Brunetti E, Grignani F, Testa U, Peschle C. Labbaye C, et al. Among authors: pasquini l. Nat Cell Biol. 2008 Jul;10(7):788-801. doi: 10.1038/ncb1741. Epub 2008 Jun 22. Nat Cell Biol. 2008. PMID: 18568019
354 results