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Page 1
Naïve Bayesian Models for Vero Cell Cytotoxicity.
Perryman AL, Patel JS, Russo R, Singleton E, Connell N, Ekins S, Freundlich JS. Perryman AL, et al. Among authors: patel js. Pharm Res. 2018 Jun 29;35(9):170. doi: 10.1007/s11095-018-2439-9. Pharm Res. 2018. PMID: 29959603 Free PMC article.
Addressing the Metabolic Stability of Antituberculars through Machine Learning.
Stratton TP, Perryman AL, Vilchèze C, Russo R, Li SG, Patel JS, Singleton E, Ekins S, Connell N, Jacobs WR Jr, Freundlich JS. Stratton TP, et al. Among authors: patel js. ACS Med Chem Lett. 2017 Sep 14;8(10):1099-1104. doi: 10.1021/acsmedchemlett.7b00299. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057058 Free PMC article.
Pruned Machine Learning Models to Predict Aqueous Solubility.
Perryman AL, Inoyama D, Patel JS, Ekins S, Freundlich JS. Perryman AL, et al. Among authors: patel js. ACS Omega. 2020 Jul 1;5(27):16562-16567. doi: 10.1021/acsomega.0c01251. eCollection 2020 Jul 14. ACS Omega. 2020. PMID: 32685821 Free PMC article.
Targeting Mycobacterium tuberculosis response to environmental cues for the development of effective antitubercular drugs.
Lavin RC, Johnson C, Ahn YM, Kremiller KM, Sherwood M, Patel JS, Pan Y, Russo R, MacGilvary NJ, Giacalone D, Kevorkian YL, Zimmerman MD, Glickman JF, Freundlich JS, Tan S. Lavin RC, et al. Among authors: patel js. PLoS Biol. 2021 Jul 28;19(7):e3001355. doi: 10.1371/journal.pbio.3001355. eCollection 2021 Jul. PLoS Biol. 2021. PMID: 34319985 Free PMC article.
Bayesian Modeling and Intrabacterial Drug Metabolism Applied to Drug-Resistant Staphylococcus aureus.
Patel JS, Norambuena J, Al-Tameemi H, Ahn YM, Perryman AL, Wang X, Daher SS, Occi J, Russo R, Park S, Zimmerman M, Ho HP, Perlin DS, Dartois V, Ekins S, Kumar P, Connell N, Boyd JM, Freundlich JS. Patel JS, et al. ACS Infect Dis. 2021 Aug 13;7(8):2508-2521. doi: 10.1021/acsinfecdis.1c00265. Epub 2021 Aug 3. ACS Infect Dis. 2021. PMID: 34342426 Free PMC article.
Small Molecule Benzothiophene with In Vivo Efficacy in a Mouse Model of Drug-Resistant Enterococcus faecium Infection.
Gallardo-Macias R, Russo R, Sherwood M, Jaskowski M, Nasser W, Sharma P, Tuckman M, Singleton E, Ho HP, Park S, Patel JS, George A, Perlin D, Zimmerman MD, Connell N, Freundlich JS. Gallardo-Macias R, et al. Among authors: patel js. J Med Chem. 2024 Jan 25;67(2):1384-1392. doi: 10.1021/acs.jmedchem.3c01846. Epub 2024 Jan 15. J Med Chem. 2024. PMID: 38225186
203 results