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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2005 2
2008 1
2009 1
2011 1
2012 2
2014 2
2015 3
2018 1
2020 1
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2023 1
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Page 1
p53 suppresses lipid droplet-fueled tumorigenesis through phosphatidylcholine.
Xu X, Wang J, Xu L, Li P, Jiang P. Xu X, et al. J Clin Invest. 2024 Jan 9;134(4):e171788. doi: 10.1172/JCI171788. J Clin Invest. 2024. PMID: 38194288 Free PMC article.
Here, by choline-free diet-associated RNA-Seq analyses, we found that the tumor suppressor p53 drives the Kennedy pathway via PCYT1B to control the growth of lipid droplets (LDs) and their fueling role in tumorigenesis. Mechanistically, through upregulation of PCYT1B …
Here, by choline-free diet-associated RNA-Seq analyses, we found that the tumor suppressor p53 drives the Kennedy pathway via PCYT1B …
Genetic Polymorphisms of LPCAT1, CHPT1 and PCYT1B and Risk of Neonatal Respiratory Distress Syndrome among a Chinese Han Population.
Shen W, Kuang P, Wang B, Zeng Q, Chen C, Lin X. Shen W, et al. Pediatr Neonatol. 2020 Jun;61(3):318-324. doi: 10.1016/j.pedneo.2019.12.012. Epub 2020 Jan 3. Pediatr Neonatol. 2020. PMID: 31964590 Free article.
The purpose of this study was to evaluate the association of polymorphisms of surfactant-lipids related genes (LPCAT1, CHPT1 and PCYT1B) with the risk/severity of respiratory distress syndrome (RDS) in preterm neonates among the Chinese Han population in Southern China. .. …
The purpose of this study was to evaluate the association of polymorphisms of surfactant-lipids related genes (LPCAT1, CHPT1 and PCYT1B …
C-reactive protein and its role in preeclampsia.
Mohaupt MG. Mohaupt MG. Hypertension. 2015 Feb;65(2):285-6. doi: 10.1161/HYPERTENSIONAHA.114.04531. Epub 2014 Dec 1. Hypertension. 2015. PMID: 25452476 Free article. No abstract available.
Genome-Wide DNA Methylation Differences between Bos indicus and Bos taurus.
Chen X, Duan X, Chong Q, Li C, Xiao H, Chen S. Chen X, et al. Animals (Basel). 2023 Jan 5;13(2):203. doi: 10.3390/ani13020203. Animals (Basel). 2023. PMID: 36670743 Free PMC article.
As a result of the results of DMR localization, we screened six genes (DNM3, INPP4B, PLD, PCYT1B, KCNN2, and SLIT3) that were tissue-specific candidates for economic traits, disease, and disease resistance in Yunnan zebu. ...
As a result of the results of DMR localization, we screened six genes (DNM3, INPP4B, PLD, PCYT1B, KCNN2, and SLIT3) that were tissue- …
Characterization of the murine CTP:phosphocholine cytidylyltransferase beta gene promoter.
Marcucci H, Elena C, Gilardoni P, Banchio C. Marcucci H, et al. Biochim Biophys Acta. 2008 May;1781(5):254-62. doi: 10.1016/j.bbalip.2008.03.006. Epub 2008 Apr 1. Biochim Biophys Acta. 2008. PMID: 18423385
In mammals, there are two genes that encode the enzyme isoforms that catalyze this reaction: Pcyt1a for CCTalpha and Pcyt1b for CCTbeta. In mouse tissues two different CCTbeta variants named CCTbeta2 and CCTbeta3 have been identified. Although little is known about Pcyt …
In mammals, there are two genes that encode the enzyme isoforms that catalyze this reaction: Pcyt1a for CCTalpha and Pcyt1b for CCTbe …
From Mendel laws to whole genetic association study to decipher the swine mulefoot phenotype.
Facioli FL, da Silva AN, Dos Santos ED, de Camargo J, Warpechowski MB, da Oliveira Cruz J, Lof LM, Zanella R. Facioli FL, et al. Res Vet Sci. 2022 Mar;143:58-65. doi: 10.1016/j.rvsc.2021.12.009. Epub 2021 Dec 20. Res Vet Sci. 2022. PMID: 34974356
Six markers were found in the intronic regions of VWC2L, CATIP, PDK3, PCYT1B, and POLA1 genes. The marker rs81277626, on SSC15:116,886,110 bp, is located in the Von Willebrand Factor C Domain (VWC2L), a possible functional candidate gene. ...
Six markers were found in the intronic regions of VWC2L, CATIP, PDK3, PCYT1B, and POLA1 genes. The marker rs81277626, on SSC15:116,88 …
Gene variants of the phosphatidylcholine synthesis pathway do not contribute to RDS in the Chinese population.
Chen YJ, Meyer J, Wambach JA, DePass K, Wegner DJ, Fan X, Zhang QY, Hillary H, Cole FS, Hamvas A. Chen YJ, et al. World J Pediatr. 2018 Feb;14(1):52-56. doi: 10.1007/s12519-017-0109-3. Epub 2018 Feb 6. World J Pediatr. 2018. PMID: 29411327
We sequenced the exons of cholinephosphate cytidylyltransferase (PCYT1B) lysophospholipid acyltransferase 1 (LPCAT1), and cholinephosphotransferase (CHPT1) genes, and analyzed both rare and common exonic variants. ...CONCLUSIONS: The population-based frequency of mutations …
We sequenced the exons of cholinephosphate cytidylyltransferase (PCYT1B) lysophospholipid acyltransferase 1 (LPCAT1), and cholinephos …
Gene structure, expression and identification of a new CTP:phosphocholine cytidylyltransferase beta isoform.
Karim M, Jackson P, Jackowski S. Karim M, et al. Biochim Biophys Acta. 2003 Jul 4;1633(1):1-12. doi: 10.1016/s1388-1981(03)00067-2. Biochim Biophys Acta. 2003. PMID: 12842190
This work defines the structures of both the murine CCT genes (Pcyt1a and Pcyt1b) and identifies a new CCT protein, CCTbeta3, with a unique amino terminus that arises from an alternate initiation exon. ...
This work defines the structures of both the murine CCT genes (Pcyt1a and Pcyt1b) and identifies a new CCT protein, CCTbeta3, with a …
Early embryonic lethality in mice with targeted deletion of the CTP:phosphocholine cytidylyltransferase alpha gene (Pcyt1a).
Wang L, Magdaleno S, Tabas I, Jackowski S. Wang L, et al. Mol Cell Biol. 2005 Apr;25(8):3357-63. doi: 10.1128/MCB.25.8.3357-3363.2005. Mol Cell Biol. 2005. PMID: 15798219 Free PMC article.
Multiple CCT isoforms, CCTalpha, CCTbeta2, and CCTbeta3, are encoded by two genes, Pcyt1a and Pcyt1b. The importance of CCTalpha in mice was investigated by deleting exons 5 and 6 in the Pcyt1a gene using the Cre-lox system. ...In contrast, enzymatic and real-time PCR data …
Multiple CCT isoforms, CCTalpha, CCTbeta2, and CCTbeta3, are encoded by two genes, Pcyt1a and Pcyt1b. The importance of CCTalpha in m …
Single ABCA3 mutations increase risk for neonatal respiratory distress syndrome.
Wambach JA, Wegner DJ, Depass K, Heins H, Druley TE, Mitra RD, An P, Zhang Q, Nogee LM, Cole FS, Hamvas A. Wambach JA, et al. Pediatrics. 2012 Dec;130(6):e1575-82. doi: 10.1542/peds.2012-0918. Epub 2012 Nov 19. Pediatrics. 2012. PMID: 23166334 Free PMC article.
We found no mutations among the RDS infants and no evidence of contribution to population-based disease burden for SFTPC, CHPT1, LPCAT1, or PCYT1B. CONCLUSIONS: In contrast to lethal neonatal RDS resulting from homozygous or compound heterozygous ABCA3 mutations, single AB …
We found no mutations among the RDS infants and no evidence of contribution to population-based disease burden for SFTPC, CHPT1, LPCAT1, or …
16 results