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Pregnane X-receptor promotes stem cell-mediated colon cancer relapse.
Planque C, Rajabi F, Grillet F, Finetti P, Bertucci F, Gironella M, Lozano JJ, Beucher B, Giraud J, Garambois V, Vincent C, Brown D, Caillo L, Kantar J, Pelegrin A, Prudhomme M, Ripoche J, Bourgaux JF, Ginestier C, Castells A, Hollande F, Pannequin J, Pascussi JM. Planque C, et al. Among authors: pelegrin a. Oncotarget. 2016 Aug 30;7(35):56558-56573. doi: 10.18632/oncotarget.10646. Oncotarget. 2016. PMID: 27448961 Free PMC article.
Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem-like Cells.
Giraud J, Failla LM, Pascussi JM, Lagerqvist EL, Ollier J, Finetti P, Bertucci F, Ya C, Gasmi I, Bourgaux JF, Prudhomme M, Mazard T, Ait-Arsa I, Houhou L, Birnbaum D, Pélegrin A, Vincent C, Ryall JG, Joubert D, Pannequin J, Hollande F. Giraud J, et al. Among authors: pelegrin a. Cancer Res. 2016 Jun 15;76(12):3618-28. doi: 10.1158/0008-5472.CAN-15-1497. Epub 2016 May 4. Cancer Res. 2016. PMID: 27197176
Symplekin promotes tumorigenicity by up-regulating claudin-2 expression.
Buchert M, Papin M, Bonnans C, Darido C, Raye WS, Garambois V, Pélegrin A, Bourgaux JF, Pannequin J, Joubert D, Hollande F. Buchert M, et al. Among authors: pelegrin a. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2628-33. doi: 10.1073/pnas.0903747107. Epub 2010 Jan 25. Proc Natl Acad Sci U S A. 2010. PMID: 20133805 Free PMC article.
Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors.
Pannequin J, Delaunay N, Buchert M, Surrel F, Bourgaux JF, Ryan J, Boireau S, Coelho J, Pélegrin A, Singh P, Shulkes A, Yim M, Baldwin GS, Pignodel C, Lambeau G, Jay P, Joubert D, Hollande F. Pannequin J, et al. Among authors: pelegrin a. Gastroenterology. 2007 Nov;133(5):1554-68. doi: 10.1053/j.gastro.2007.08.023. Epub 2007 Oct 24. Gastroenterology. 2007. PMID: 17920061
The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells.
Estupina P, Fontayne A, Barret JM, Kersual N, Dubreuil O, Le Blay M, Pichard A, Jarlier M, Pugnière M, Chauvin M, Chardès T, Pouget JP, Deshayes E, Rossignol A, Abache T, de Romeuf C, Terrier A, Verhaeghe L, Gaucher C, Prost JF, Pèlegrin A, Navarro-Teulon I. Estupina P, et al. Among authors: pelegrin a. Oncotarget. 2017 Jun 6;8(23):37061-37079. doi: 10.18632/oncotarget.15715. Oncotarget. 2017. PMID: 28427157 Free PMC article.
Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in gemcitabine-resistant pancreatic cancer models.
Rabia E, Garambois V, Hubert J, Bruciamacchie M, Pirot N, Delpech H, Broyon M, Theillet C, Colombo PE, Vie N, Tosi D, Gongora C, Khellaf L, Jarlier M, Radosevic-Robin N, Chardès T, Pèlegrin A, Larbouret C. Rabia E, et al. Among authors: pelegrin a. MAbs. 2021 Jan-Dec;13(1):1914883. doi: 10.1080/19420862.2021.1914883. MAbs. 2021. PMID: 33876707 Free PMC article.
Anti-Müllerian hormone concentration regulates activin receptor-like kinase-2/3 expression levels with opposing effects on ovarian cancer cell survival.
Chauvin M, Garambois V, Choblet S, Colombo PE, Chentouf M, Gros L, De Brauwere DP, Duonor-Cerutti M, Dumas K, Robert B, Jarlier M, Martineau P, Navarro-Teulon I, Pépin D, Chardès T, Pèlegrin A. Chauvin M, et al. Among authors: pelegrin a. Int J Oncol. 2021 Jul;59(1):43. doi: 10.3892/ijo.2021.5223. Epub 2021 May 20. Int J Oncol. 2021. PMID: 34013359 Free PMC article.
166 results