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Osteoprotegerin protects against muscular dystrophy.
Dufresne SS, Dumont NA, Bouchard P, Lavergne É, Penninger JM, Frenette J. Dufresne SS, et al. Among authors: penninger jm. Am J Pathol. 2015 Apr;185(4):920-6. doi: 10.1016/j.ajpath.2015.01.006. Epub 2015 Feb 21. Am J Pathol. 2015. PMID: 25708645 Free article.
Muscle RANK is a key regulator of Ca2+ storage, SERCA activity, and function of fast-twitch skeletal muscles.
Dufresne SS, Dumont NA, Boulanger-Piette A, Fajardo VA, Gamu D, Kake-Guena SA, David RO, Bouchard P, Lavergne É, Penninger JM, Pape PC, Tupling AR, Frenette J. Dufresne SS, et al. Among authors: penninger jm. Am J Physiol Cell Physiol. 2016 Apr 15;310(8):C663-72. doi: 10.1152/ajpcell.00285.2015. Epub 2016 Jan 28. Am J Physiol Cell Physiol. 2016. PMID: 26825123 Free PMC article.
Genetic deletion of muscle RANK or selective inhibition of RANKL is not as effective as full-length OPG-fc in mitigating muscular dystrophy.
Dufresne SS, Boulanger-Piette A, Bossé S, Argaw A, Hamoudi D, Marcadet L, Gamu D, Fajardo VA, Yagita H, Penninger JM, Russell Tupling A, Frenette J. Dufresne SS, et al. Among authors: penninger jm. Acta Neuropathol Commun. 2018 Apr 24;6(1):31. doi: 10.1186/s40478-018-0533-1. Acta Neuropathol Commun. 2018. PMID: 29699580 Free PMC article.
Central control of fever and female body temperature by RANKL/RANK.
Hanada R, Leibbrandt A, Hanada T, Kitaoka S, Furuyashiki T, Fujihara H, Trichereau J, Paolino M, Qadri F, Plehm R, Klaere S, Komnenovic V, Mimata H, Yoshimatsu H, Takahashi N, von Haeseler A, Bader M, Kilic SS, Ueta Y, Pifl C, Narumiya S, Penninger JM. Hanada R, et al. Among authors: penninger jm. Nature. 2009 Nov 26;462(7272):505-9. doi: 10.1038/nature08596. Nature. 2009. PMID: 19940926
Role of RANKL and RANK in bone loss and arthritis.
Jones DH, Kong YY, Penninger JM. Jones DH, et al. Among authors: penninger jm. Ann Rheum Dis. 2002 Nov;61 Suppl 2(Suppl 2):ii32-9. doi: 10.1136/ard.61.suppl_2.ii32. Ann Rheum Dis. 2002. PMID: 12379618 Free PMC article. Review.
RANKL and RANK as novel therapeutic targets for arthritis.
Nakashima T, Wada T, Penninger JM. Nakashima T, et al. Among authors: penninger jm. Curr Opin Rheumatol. 2003 May;15(3):280-7. doi: 10.1097/00002281-200305000-00016. Curr Opin Rheumatol. 2003. PMID: 12707582 Review.
Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes.
Pospisilik JA, Knauf C, Joza N, Benit P, Orthofer M, Cani PD, Ebersberger I, Nakashima T, Sarao R, Neely G, Esterbauer H, Kozlov A, Kahn CR, Kroemer G, Rustin P, Burcelin R, Penninger JM. Pospisilik JA, et al. Among authors: penninger jm. Cell. 2007 Nov 2;131(3):476-91. doi: 10.1016/j.cell.2007.08.047. Cell. 2007. PMID: 17981116 Free article.
632 results