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Page 1
Deregulation of miR-324/KISS1/kisspeptin in early ectopic pregnancy: mechanistic findings with clinical and diagnostic implications.
Romero-Ruiz A, Avendaño MS, Dominguez F, Lozoya T, Molina-Abril H, Sangiao-Alvarellos S, Gurrea M, Lara-Chica M, Fernandez-Sanchez M, Torres-Jimenez E, Perdices-Lopez C, Abbara A, Steffani L, Calzado MA, Dhillo WS, Pellicer A, Tena-Sempere M. Romero-Ruiz A, et al. Among authors: perdices lopez c. Am J Obstet Gynecol. 2019 May;220(5):480.e1-480.e17. doi: 10.1016/j.ajog.2019.01.228. Epub 2019 Jan 29. Am J Obstet Gynecol. 2019. PMID: 30707968 Free article.
Molecular diagnosis of polycystic ovary syndrome in obese and non-obese women by targeted plasma miRNA profiling.
Romero-Ruiz A, Pineda B, Ovelleiro D, Perdices-Lopez C, Torres E, Vazquez MJ, Guler I, Jiménez Á, Pineda R, Persano M, Romero-Baldonado C, Arjona JE, Lorente J, Muñoz C, Paz E, Garcia-Maceira FI, Arjona-Sánchez Á, Tena-Sempere M. Romero-Ruiz A, et al. Among authors: perdices lopez c. Eur J Endocrinol. 2021 Oct 8;185(5):637-652. doi: 10.1530/EJE-21-0552. Eur J Endocrinol. 2021. PMID: 34403358
Connecting nutritional deprivation and pubertal inhibition via GRK2-mediated repression of kisspeptin actions in GnRH neurons.
Perdices-Lopez C, Avendaño MS, Barroso A, Gaytán F, Ruiz-Pino F, Vázquez MJ, Leon S, Song YB, Sobrino V, Heras V, Romero-Ruiz A, Roa J, Mayor F Jr, Murga C, Pinilla L, Kaiser UB, Tena-Sempere M. Perdices-Lopez C, et al. Metabolism. 2022 Apr;129:155141. doi: 10.1016/j.metabol.2022.155141. Epub 2022 Jan 22. Metabolism. 2022. PMID: 35074314 Free PMC article.
Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female mice.
Roa J, Ruiz-Cruz M, Ruiz-Pino F, Onieva R, Vazquez MJ, Sanchez-Tapia MJ, Ruiz-Rodriguez JM, Sobrino V, Barroso A, Heras V, Velasco I, Perdices-Lopez C, Ohlsson C, Avendaño MS, Prevot V, Poutanen M, Pinilla L, Gaytan F, Tena-Sempere M. Roa J, et al. Among authors: perdices lopez c. Nat Commun. 2022 Aug 9;13(1):4663. doi: 10.1038/s41467-022-32347-4. Nat Commun. 2022. PMID: 35945211 Free PMC article.
Kisspeptin treatment induces gonadotropic responses and rescues ovulation in a subset of preclinical models and women with polycystic ovary syndrome.
Romero-Ruiz A, Skorupskaite K, Gaytan F, Torres E, Perdices-Lopez C, Mannaerts BM, Qi S, Leon S, Manfredi-Lozano M, Lopez-Rodriguez C, Avendaño MS, Sanchez-Garrido MA, Vazquez MJ, Pinilla L, van Duin M, Kohout TA, Anderson RA, Tena-Sempere M. Romero-Ruiz A, et al. Among authors: perdices lopez c. Hum Reprod. 2019 Dec 1;34(12):2495-2512. doi: 10.1093/humrep/dez205. Hum Reprod. 2019. PMID: 31820802 Free PMC article. Clinical Trial.
Neonatal exposure to androgens dynamically alters gut microbiota architecture.
Barroso A, Santos-Marcos JA, Perdices-Lopez C, Vega-Rojas A, Sanchez-Garrido MA, Krylova Y, Molina-Abril H, Ohlsson C, Perez-Martinez P, Poutanen M, Lopez-Miranda J, Tena-Sempere M, Camargo A. Barroso A, et al. Among authors: perdices lopez c. J Endocrinol. 2020 Oct;247(1):69-85. doi: 10.1530/JOE-20-0277. J Endocrinol. 2020. PMID: 32755996 Free article.
Interplay between gonadal hormones and postnatal overfeeding in defining sex-dependent differences in gut microbiota architecture.
Santos-Marcos JA, Barroso A, Rangel-Zuñiga OA, Perdices-Lopez C, Haro C, Sanchez-Garrido MA, Molina-Abril H, Ohlsson C, Perez-Martinez P, Poutanen M, Lopez-Miranda J, Perez-Jimenez F, Tena-Sempere M, Camargo A. Santos-Marcos JA, et al. Among authors: perdices lopez c. Aging (Albany NY). 2020 Oct 27;12(20):19979-20000. doi: 10.18632/aging.104140. Epub 2020 Oct 27. Aging (Albany NY). 2020. PMID: 33107844 Free PMC article.