Perera RL - Search Results

1

A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome.

Kilkenny ML, De Piccoli G, Perera RL, Labib K, Pellegrini L. Kilkenny ML, et al. Among authors: perera rl. J Biol Chem. 2012 Jul 6;287(28):23740-7. doi: 10.1074/jbc.M112.368951. Epub 2012 May 16. J Biol Chem. 2012. PMID: 22593576 Free PMC article.

2

Shared active site architecture between the large subunit of eukaryotic primase and DNA photolyase.

Sauguet L, Klinge S, Perera RL, Maman JD, Pellegrini L. Sauguet L, et al. Among authors: perera rl. PLoS One. 2010 Apr 9;5(4):e10083. doi: 10.1371/journal.pone.0010083. PLoS One. 2010. PMID: 20404922 Free PMC article.

3

Mechanism for priming DNA synthesis by yeast DNA polymerase α.

Perera RL, Torella R, Klinge S, Kilkenny ML, Maman JD, Pellegrini L. Perera RL, et al. Elife. 2013 Apr 2;2:e00482. doi: 10.7554/eLife.00482. Elife. 2013. PMID: 23599895 Free PMC article.

4

Structures of human primase reveal design of nucleotide elongation site and mode of Pol α tethering.

Kilkenny ML, Longo MA, Perera RL, Pellegrini L. Kilkenny ML, et al. Among authors: perera rl. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):15961-6. doi: 10.1073/pnas.1311185110. Epub 2013 Sep 16. Proc Natl Acad Sci U S A. 2013. PMID: 24043831 Free PMC article.

5

A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome.

Simon AC, Zhou JC, Perera RL, van Deursen F, Evrin C, Ivanova ME, Kilkenny ML, Renault L, Kjaer S, Matak-Vinković D, Labib K, Costa A, Pellegrini L. Simon AC, et al. Among authors: perera rl. Nature. 2014 Jun 12;510(7504):293-297. doi: 10.1038/nature13234. Epub 2014 May 4. Nature. 2014. PMID: 24805245 Free PMC article.

6

Flexible tethering of primase and DNA Pol α in the eukaryotic primosome.

Núñez-Ramírez R, Klinge S, Sauguet L, Melero R, Recuero-Checa MA, Kilkenny M, Perera RL, García-Alvarez B, Hall RJ, Nogales E, Pellegrini L, Llorca O. Núñez-Ramírez R, et al. Among authors: perera rl. Nucleic Acids Res. 2011 Oct;39(18):8187-99. doi: 10.1093/nar/gkr534. Epub 2011 Jun 28. Nucleic Acids Res. 2011. PMID: 21715379 Free PMC article.

7

A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA.

Yates LA, Aramayo RJ, Pokhrel N, Caldwell CC, Kaplan JA, Perera RL, Spies M, Antony E, Zhang X. Yates LA, et al. Among authors: perera rl. Nat Commun. 2018 Dec 21;9(1):5447. doi: 10.1038/s41467-018-07883-7. Nat Commun. 2018. PMID: 30575763 Free PMC article.

8

Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance.

Wohlkonig A, Chan PF, Fosberry AP, Homes P, Huang J, Kranz M, Leydon VR, Miles TJ, Pearson ND, Perera RL, Shillings AJ, Gwynn MN, Bax BD. Wohlkonig A, et al. Among authors: perera rl. Nat Struct Mol Biol. 2010 Sep;17(9):1152-3. doi: 10.1038/nsmb.1892. Epub 2010 Aug 29. Nat Struct Mol Biol. 2010. PMID: 20802486

9

Identification of soluble protein fragments by gene fragmentation and genetic selection.

Dyson MR, Perera RL, Shadbolt SP, Biderman L, Bromek K, Murzina NV, McCafferty J. Dyson MR, et al. Among authors: perera rl. Nucleic Acids Res. 2008 May;36(9):e51. doi: 10.1093/nar/gkn151. Epub 2008 Apr 17. Nucleic Acids Res. 2008. PMID: 18420658 Free PMC article.

10

Production of soluble mammalian proteins in Escherichia coli: identification of protein features that correlate with successful expression.

Dyson MR, Shadbolt SP, Vincent KJ, Perera RL, McCafferty J. Dyson MR, et al. Among authors: perera rl. BMC Biotechnol. 2004 Dec 14;4:32. doi: 10.1186/1472-6750-4-32. BMC Biotechnol. 2004. PMID: 15598350 Free PMC article.

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