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Development of a platinum complex as an anti-amyloid agent for the therapy of Alzheimer's disease.
Kenche VB, Hung LW, Perez K, Volitakes I, Ciccotosto G, Kwok J, Critch N, Sherratt N, Cortes M, Lal V, Masters CL, Murakami K, Cappai R, Adlard PA, Barnham KJ. Kenche VB, et al. Among authors: perez k. Angew Chem Int Ed Engl. 2013 Mar 18;52(12):3374-8. doi: 10.1002/anie.201209885. Epub 2013 Feb 10. Angew Chem Int Ed Engl. 2013. PMID: 23401085 No abstract available.
Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease.
Barnham KJ, Kenche VB, Ciccotosto GD, Smith DP, Tew DJ, Liu X, Perez K, Cranston GA, Johanssen TJ, Volitakis I, Bush AI, Masters CL, White AR, Smith JP, Cherny RA, Cappai R. Barnham KJ, et al. Among authors: perez k. Proc Natl Acad Sci U S A. 2008 May 13;105(19):6813-8. doi: 10.1073/pnas.0800712105. Epub 2008 May 7. Proc Natl Acad Sci U S A. 2008. PMID: 18463291 Free PMC article.
Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation.
Crouch PJ, Hung LW, Adlard PA, Cortes M, Lal V, Filiz G, Perez KA, Nurjono M, Caragounis A, Du T, Laughton K, Volitakis I, Bush AI, Li QX, Masters CL, Cappai R, Cherny RA, Donnelly PS, White AR, Barnham KJ. Crouch PJ, et al. Among authors: perez ka. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):381-6. doi: 10.1073/pnas.0809057106. Epub 2009 Jan 2. Proc Natl Acad Sci U S A. 2009. PMID: 19122148 Free PMC article.
Restored degradation of the Alzheimer's amyloid-beta peptide by targeting amyloid formation.
Crouch PJ, Tew DJ, Du T, Nguyen DN, Caragounis A, Filiz G, Blake RE, Trounce IA, Soon CP, Laughton K, Perez KA, Li QX, Cherny RA, Masters CL, Barnham KJ, White AR. Crouch PJ, et al. Among authors: perez ka. J Neurochem. 2009 Mar;108(5):1198-207. doi: 10.1111/j.1471-4159.2009.05870.x. Epub 2009 Jan 7. J Neurochem. 2009. PMID: 19141082 Free article.
635 results