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In vitro evolution of itraconazole resistance in Aspergillus fumigatus involves multiple mechanisms of resistance.
da Silva Ferreira ME, Capellaro JL, dos Reis Marques E, Malavazi I, Perlin D, Park S, Anderson JB, Colombo AL, Arthington-Skaggs BA, Goldman MH, Goldman GH. da Silva Ferreira ME, et al. Antimicrob Agents Chemother. 2004 Nov;48(11):4405-13. doi: 10.1128/AAC.48.11.4405-4413.2004. Antimicrob Agents Chemother. 2004. PMID: 15504870 Free PMC article.
Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates.
Park S, Kelly R, Kahn JN, Robles J, Hsu MJ, Register E, Li W, Vyas V, Fan H, Abruzzo G, Flattery A, Gill C, Chrebet G, Parent SA, Kurtz M, Teppler H, Douglas CM, Perlin DS. Park S, et al. Among authors: perlin ds. Antimicrob Agents Chemother. 2005 Aug;49(8):3264-73. doi: 10.1128/AAC.49.8.3264-3273.2005. Antimicrob Agents Chemother. 2005. PMID: 16048935 Free PMC article. Clinical Trial.
352 results