Pesce E - Search Results

1

Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel.

Pedemonte N, Bertozzi F, Caci E, Sorana F, Di Fruscia P, Tomati V, Ferrera L, Rodríguez-Gimeno A, Berti F, Pesce E, Sondo E, Gianotti A, Scudieri P, Bandiera T, Galietta LJV. Pedemonte N, et al. Among authors: pesce e. Sci Adv. 2020 Feb 21;6(8):eaay9669. doi: 10.1126/sciadv.aay9669. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32128418 Free PMC article.

2

The search for a common structural moiety among selected pharmacological correctors of the mutant CFTR chloride channel.

Nieddu E, Pollarolo B, Mazzei MT, Anzaldi M, Schenone S, Pedemonte N, Pesce E, Galietta LJ, Mazzei M. Nieddu E, et al. Among authors: pesce e. Future Med Chem. 2014;6(17):1857-68. doi: 10.4155/fmc.14.118. Future Med Chem. 2014. PMID: 25495980

3

Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.

Pesce E, Bellotti M, Liessi N, Guariento S, Damonte G, Cichero E, Galatini A, Salis A, Gianotti A, Pedemonte N, Zegarra-Moran O, Fossa P, Galietta LJ, Millo E. Pesce E, et al. Eur J Med Chem. 2015 Jun 24;99:14-35. doi: 10.1016/j.ejmech.2015.05.030. Epub 2015 May 28. Eur J Med Chem. 2015. PMID: 26041577

4

Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation.

Tomati V, Sondo E, Armirotti A, Caci E, Pesce E, Marini M, Gianotti A, Jeon YJ, Cilli M, Pistorio A, Mastracci L, Ravazzolo R, Scholte B, Ronai Z, Galietta LJ, Pedemonte N. Tomati V, et al. Among authors: pesce e. Sci Rep. 2015 Jul 17;5:12138. doi: 10.1038/srep12138. Sci Rep. 2015. PMID: 26183966 Free PMC article.

5

Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel.

Pesce E, Gorrieri G, Sirci F, Napolitano F, Carrella D, Caci E, Tomati V, Zegarra-Moran O, di Bernardo D, Galietta LJ. Pesce E, et al. J Cyst Fibros. 2016 Jul;15(4):425-35. doi: 10.1016/j.jcf.2016.02.009. Epub 2016 Mar 10. J Cyst Fibros. 2016. PMID: 26971626 Free article.

6

RNF5, DAB2 and Friends: Novel Drug Targets for Cystic Fibrosis.

Sondo E, Pesce E, Tomati V, Marini M, Pedemonte N. Sondo E, et al. Among authors: pesce e. Curr Pharm Des. 2017;23(1):176-186. doi: 10.2174/1381612822666161006161033. Curr Pharm Des. 2017. PMID: 27719636 Review.

7

Therapeutic approaches to CFTR dysfunction: From discovery to drug development.

Li H, Pesce E, Sheppard DN, Singh AK, Pedemonte N. Li H, et al. Among authors: pesce e. J Cyst Fibros. 2018 Mar;17(2S):S14-S21. doi: 10.1016/j.jcf.2017.08.013. Epub 2017 Sep 12. J Cyst Fibros. 2018. PMID: 28916430 Free article. Review.

8

High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel.

Tomati V, Pesce E, Caci E, Sondo E, Scudieri P, Marini M, Amato F, Castaldo G, Ravazzolo R, Galietta LJV, Pedemonte N. Tomati V, et al. Among authors: pesce e. J Biol Chem. 2018 Jan 26;293(4):1203-1217. doi: 10.1074/jbc.M117.816595. Epub 2017 Nov 20. J Biol Chem. 2018. PMID: 29158263 Free PMC article.

9

Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools.

Liessi N, Cichero E, Pesce E, Arkel M, Salis A, Tomati V, Paccagnella M, Damonte G, Tasso B, Galietta LJV, Pedemonte N, Fossa P, Millo E. Liessi N, et al. Among authors: pesce e. Eur J Med Chem. 2018 Jan 20;144:179-200. doi: 10.1016/j.ejmech.2017.12.030. Epub 2017 Dec 8. Eur J Med Chem. 2018. PMID: 29272749

10

Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia.

Tomati V, Caci E, Ferrera L, Pesce E, Sondo E, Cholon DM, Quinney NL, Boyles SE, Armirotti A, Ravazzolo R, Galietta LJ, Gentzsch M, Pedemonte N. Tomati V, et al. Among authors: pesce e. JCI Insight. 2018 Feb 8;3(3):e98699. doi: 10.1172/jci.insight.98699. eCollection 2018 Feb 8. JCI Insight. 2018. PMID: 29415893 Free PMC article.

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