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Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis.
Johnston KL, Ford L, Umareddy I, Townson S, Specht S, Pfarr K, Hoerauf A, Altmeyer R, Taylor MJ. Johnston KL, et al. Among authors: pfarr k. Int J Parasitol Drugs Drug Resist. 2014 Sep 16;4(3):278-86. doi: 10.1016/j.ijpddr.2014.09.001. eCollection 2014 Dec. Int J Parasitol Drugs Drug Resist. 2014. PMID: 25516838 Free PMC article.
Doxycycline as a novel strategy against bancroftian filariasis-depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production.
Hoerauf A, Mand S, Fischer K, Kruppa T, Marfo-Debrekyei Y, Debrah AY, Pfarr KM, Adjei O, Büttner DW. Hoerauf A, et al. Among authors: pfarr km. Med Microbiol Immunol. 2003 Nov;192(4):211-6. doi: 10.1007/s00430-002-0174-6. Epub 2003 Mar 5. Med Microbiol Immunol. 2003. PMID: 12684759 Clinical Trial.
Evidence against Wolbachia symbiosis in Loa loa.
McGarry HF, Pfarr K, Egerton G, Hoerauf A, Akue JP, Enyong P, Wanji S, Kläger SL, Bianco AE, Beeching NJ, Taylor MJ. McGarry HF, et al. Among authors: pfarr k. Filaria J. 2003 May 2;2(1):9. doi: 10.1186/1475-2883-2-9. Filaria J. 2003. PMID: 12816546 Free PMC article.
109 results