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Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity.
Münzker J, Haase N, Till A, Sucher R, Haange SB, Nemetschke L, Gnad T, Jäger E, Chen J, Riede SJ, Chakaroun R, Massier L, Kovacs P, Ost M, Rolle-Kampczyk U, Jehmlich N, Weiner J, Heiker JT, Klöting N, Seeger G, Morawski M, Keitel V, Pfeifer A, von Bergen M, Heeren J, Krügel U, Fenske WK. Münzker J, et al. Among authors: pfeifer a. Microbiome. 2022 Jun 24;10(1):96. doi: 10.1186/s40168-022-01264-5. Microbiome. 2022. PMID: 35739571 Free PMC article.
Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors.
Gnad T, Scheibler S, von Kügelgen I, Scheele C, Kilić A, Glöde A, Hoffmann LS, Reverte-Salisa L, Horn P, Mutlu S, El-Tayeb A, Kranz M, Deuther-Conrad W, Brust P, Lidell ME, Betz MJ, Enerbäck S, Schrader J, Yegutkin GG, Müller CE, Pfeifer A. Gnad T, et al. Among authors: pfeifer a. Nature. 2014 Dec 18;516(7531):395-9. doi: 10.1038/nature13816. Epub 2014 Oct 15. Nature. 2014. PMID: 25317558
The Gq signalling pathway inhibits brown and beige adipose tissue.
Klepac K, Kilić A, Gnad T, Brown LM, Herrmann B, Wilderman A, Balkow A, Glöde A, Simon K, Lidell ME, Betz MJ, Enerbäck S, Wess J, Freichel M, Blüher M, König G, Kostenis E, Insel PA, Pfeifer A. Klepac K, et al. Among authors: pfeifer a. Nat Commun. 2016 Mar 9;7:10895. doi: 10.1038/ncomms10895. Nat Commun. 2016. PMID: 26955961 Free PMC article.
Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity.
Chen Y, Buyel JJ, Hanssen MJ, Siegel F, Pan R, Naumann J, Schell M, van der Lans A, Schlein C, Froehlich H, Heeren J, Virtanen KA, van Marken Lichtenbelt W, Pfeifer A. Chen Y, et al. Among authors: pfeifer a. Nat Commun. 2016 Apr 27;7:11420. doi: 10.1038/ncomms11420. Nat Commun. 2016. PMID: 27117818 Free PMC article.
A novel thermoregulatory role for PDE10A in mouse and human adipocytes.
Hankir MK, Kranz M, Gnad T, Weiner J, Wagner S, Deuther-Conrad W, Bronisch F, Steinhoff K, Luthardt J, Klöting N, Hesse S, Seibyl JP, Sabri O, Heiker JT, Blüher M, Pfeifer A, Brust P, Fenske WK. Hankir MK, et al. Among authors: pfeifer a. EMBO Mol Med. 2016 Jul 1;8(7):796-812. doi: 10.15252/emmm.201506085. Print 2016 Jul. EMBO Mol Med. 2016. PMID: 27247380 Free PMC article.
Cannabinoid Type 1 Receptors Are Upregulated During Acute Activation of Brown Adipose Tissue.
Lahesmaa M, Eriksson O, Gnad T, Oikonen V, Bucci M, Hirvonen J, Koskensalo K, Teuho J, Niemi T, Taittonen M, Lahdenpohja S, U Din M, Haaparanta-Solin M, Pfeifer A, Virtanen KA, Nuutila P. Lahesmaa M, et al. Among authors: pfeifer a. Diabetes. 2018 Jul;67(7):1226-1236. doi: 10.2337/db17-1366. Epub 2018 Apr 12. Diabetes. 2018. PMID: 29650773 Free article. Clinical Trial.
Impact of obesity and aging on crestal alveolar bone height in mice.
Damanaki A, Memmert S, Nokhbehsaim M, Sanyal A, Gnad T, Pfeifer A, Deschner J. Damanaki A, et al. Among authors: pfeifer a. Ann Anat. 2018 Jul;218:227-235. doi: 10.1016/j.aanat.2018.04.005. Epub 2018 May 4. Ann Anat. 2018. PMID: 29730468
425 results