Pfeifer T - Search Results

1

Identification of substrate-specific inhibitors of cathepsin K through high-throughput screening.

Law S, Du X, Panwar P, Honson NS, Pfeifer T, Roberge M, Brömme D. Law S, et al. Among authors: pfeifer t. Biochem J. 2019 Feb 5;476(3):499-512. doi: 10.1042/BCJ20180851. Biochem J. 2019. PMID: 30622151

2

Inhibitors of the influenza A virus M2 proton channel discovered using a high-throughput yeast growth restoration assay.

Balgi AD, Wang J, Cheng DY, Ma C, Pfeifer TA, Shimizu Y, Anderson HJ, Pinto LH, Lamb RA, DeGrado WF, Roberge M. Balgi AD, et al. PLoS One. 2013;8(2):e55271. doi: 10.1371/journal.pone.0055271. Epub 2013 Feb 1. PLoS One. 2013. PMID: 23383318 Free PMC article.

3

Development of fluorescent peptide substrates and assays for the key autophagy-initiating cysteine protease enzyme, ATG4B.

Vezenkov L, Honson NS, Kumar NS, Bosc D, Kovacic S, Nguyen TG, Pfeifer TA, Young RN. Vezenkov L, et al. Bioorg Med Chem. 2015 Jul 1;23(13):3237-47. doi: 10.1016/j.bmc.2015.04.064. Epub 2015 Apr 28. Bioorg Med Chem. 2015. PMID: 25979376

4

Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen.

Ramón-García S, Ng C, Anderson H, Chao JD, Zheng X, Pfeifer T, Av-Gay Y, Roberge M, Thompson CJ. Ramón-García S, et al. Among authors: pfeifer t. Antimicrob Agents Chemother. 2011 Aug;55(8):3861-9. doi: 10.1128/AAC.00474-11. Epub 2011 May 16. Antimicrob Agents Chemother. 2011. PMID: 21576426 Free PMC article.

5

Identification and characterization of a selective allosteric antagonist of human P2X4 receptor channels.

Ase AR, Honson NS, Zaghdane H, Pfeifer TA, Séguéla P. Ase AR, et al. Mol Pharmacol. 2015 Apr;87(4):606-16. doi: 10.1124/mol.114.096222. Epub 2015 Jan 16. Mol Pharmacol. 2015. PMID: 25597706

6

Compounds producing an effective combinatorial regimen for disruption of HIV-1 latency.

Hashemi P, Barreto K, Bernhard W, Lomness A, Honson N, Pfeifer TA, Harrigan PR, Sadowski I. Hashemi P, et al. EMBO Mol Med. 2018 Feb;10(2):160-174. doi: 10.15252/emmm.201708193. EMBO Mol Med. 2018. PMID: 29246970 Free PMC article.

7

A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B.

Bosc D, Vezenkov L, Bortnik S, An J, Xu J, Choutka C, Hannigan AM, Kovacic S, Loo S, Clark PGK, Chen G, Guay-Ross RN, Yang K, Dragowska WH, Zhang F, Go NE, Leung A, Honson NS, Pfeifer TA, Gleave M, Bally M, Jones SJ, Gorski SM, Young RN. Bosc D, et al. Among authors: pfeifer ta. Sci Rep. 2018 Aug 3;8(1):11653. doi: 10.1038/s41598-018-29900-x. Sci Rep. 2018. PMID: 30076329 Free PMC article.

8

Novel spirothiazamenthane inhibitors of the influenza A M2 proton channel.

Arns S, Balgi AD, Shimizu Y, Pfeifer TA, Kumar N, Shidmoossavee FS, Sun S, Tai SS, Agafitei O, Jaquith JB, Bourque E, Niikura M, Roberge M. Arns S, et al. Eur J Med Chem. 2016 Sep 14;120:64-73. doi: 10.1016/j.ejmech.2016.05.008. Epub 2016 May 7. Eur J Med Chem. 2016. PMID: 27187859

9

Development of fluorescent substrates and assays for the key autophagy-related cysteine protease enzyme, ATG4B.

Nguyen TG, Honson NS, Arns S, Davis TL, Dhe-Paganon S, Kovacic S, Kumar NS, Pfeifer TA, Young RN. Nguyen TG, et al. Assay Drug Dev Technol. 2014 Apr;12(3):176-89. doi: 10.1089/adt.2013.561. Assay Drug Dev Technol. 2014. PMID: 24735444 Free PMC article.

10

Novel small molecules potentiate premature termination codon readthrough by aminoglycosides.

Baradaran-Heravi A, Balgi AD, Zimmerman C, Choi K, Shidmoossavee FS, Tan JS, Bergeaud C, Krause A, Flibotte S, Shimizu Y, Anderson HJ, Mouly V, Jan E, Pfeifer T, Jaquith JB, Roberge M. Baradaran-Heravi A, et al. Among authors: pfeifer t. Nucleic Acids Res. 2016 Aug 19;44(14):6583-98. doi: 10.1093/nar/gkw638. Epub 2016 Jul 12. Nucleic Acids Res. 2016. PMID: 27407112 Free PMC article.

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