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Year Number of Results
1989 1
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2011 5
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209 results

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Page 1
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1.
Luo JQ, Yang TW, Wu J, Lai HH, Zou LB, Chen WB, Zhou XM, Lv DJ, Cen SR, Long ZN, Mao YY, Zheng PX, Su XH, Xian ZY, Shu FP, Mao XM. Luo JQ, et al. Cell Death Dis. 2023 Aug 4;14(8):502. doi: 10.1038/s41419-023-06007-4. Cell Death Dis. 2023. PMID: 37542027 Free PMC article.
Tumor-derived exosomes and their contents promote cancer metastasis. Phosphoglycerate mutase 1 (PGAM1) is involved in various cancer-related processes. Nevertheless, the underlying mechanism of exosomal PGAM1 in prostate cancer (PCa) metastasis remains unclear. ...I …
Tumor-derived exosomes and their contents promote cancer metastasis. Phosphoglycerate mutase 1 (PGAM1) is involved in various cancer- …
PGAM1 Inhibition Promotes HCC Ferroptosis and Synergizes with Anti-PD-1 Immunotherapy.
Zheng Y, Wang Y, Lu Z, Wan J, Jiang L, Song D, Wei C, Gao C, Shi G, Zhou J, Fan J, Ke A, Zhou L, Cai J. Zheng Y, et al. Adv Sci (Weinh). 2023 Oct;10(29):e2301928. doi: 10.1002/advs.202301928. Epub 2023 Sep 14. Adv Sci (Weinh). 2023. PMID: 37705495 Free PMC article.
PGAM1 is highly expressed in HCC and associated with a poor prognosis and a poor response to immunotherapy. ...Targeting PGAM1 can be a promising new strategy of "killing two birds with one stone" for HCC treatment....
PGAM1 is highly expressed in HCC and associated with a poor prognosis and a poor response to immunotherapy. ...Targeting PGAM1 …
Targeting PGAM1 in cancer: An emerging therapeutic opportunity.
Yang GJ, Tao F, Zhong HJ, Yang C, Chen J. Yang GJ, et al. Eur J Med Chem. 2022 Dec 15;244:114798. doi: 10.1016/j.ejmech.2022.114798. Epub 2022 Oct 3. Eur J Med Chem. 2022. PMID: 36215859 Review.
The critical roles of PGAM1 in tumorigenesis make it a promising theranostical target for cancer. ...This review provides insights into structure, function, and regulation of PGAM1, summarizes its mechanism in tumorigenesis, reviews the advanced status of PGAM1 …
The critical roles of PGAM1 in tumorigenesis make it a promising theranostical target for cancer. ...This review provides insights in …
PGAM1 regulation of ASS1 contributes to the progression of breast cancer through the cAMP/AMPK/CEBPB pathway.
Liu M, Li R, Wang M, Liu T, Zhou Q, Zhang D, Wang J, Shen M, Ren X, Sun Q. Liu M, et al. Mol Oncol. 2022 Aug;16(15):2843-2860. doi: 10.1002/1878-0261.13259. Epub 2022 Jun 27. Mol Oncol. 2022. PMID: 35674458 Free PMC article.
However, the precise role and other biological functions of PGAM1 remain unclear. Here, we report that PGAM1 expression is upregulated and related to poor prognosis in patients with breast cancer (BC). ...Importantly, we demonstrated that PGAM1 negatively reg …
However, the precise role and other biological functions of PGAM1 remain unclear. Here, we report that PGAM1 expression is upr …
S1P/S1PR3 axis promotes aerobic glycolysis by YAP/c-MYC/PGAM1 axis in osteosarcoma.
Shen Y, Zhao S, Wang S, Pan X, Zhang Y, Xu J, Jiang Y, Li H, Zhang Q, Gao J, Yang Q, Zhou Y, Jiang S, Yang H, Zhang Z, Zhang R, Li J, Zhou D. Shen Y, et al. EBioMedicine. 2019 Feb;40:210-223. doi: 10.1016/j.ebiom.2018.12.038. Epub 2018 Dec 23. EBioMedicine. 2019. PMID: 30587459 Free PMC article.
Chromatin immunoprecipitation was used to investigate the binding capability of PGAM1 and YAP or c-MYC. Moreover, the activities of promoter were determined by the luciferase reporter assay. ...Mechanistically, the S1P/S1PR3 axis inhibited the phosphorylation of YAP and pr …
Chromatin immunoprecipitation was used to investigate the binding capability of PGAM1 and YAP or c-MYC. Moreover, the activities of p …
PGAM1 Promotes Glycolytic Metabolism and Paclitaxel Resistance via Pyruvic Acid Production in Ovarian Cancer Cells.
Feng Y, Zhang X, Zhang S, Xu S, Chen X, Zhou C, Xi Y, Xie X, Lu W. Feng Y, et al. Front Biosci (Landmark Ed). 2022 Sep 16;27(9):262. doi: 10.31083/j.fbl2709262. Front Biosci (Landmark Ed). 2022. PMID: 36224008 Free article.
Down-regulation of PGAM1 in SKOV3-TR30 cells resulted in decreased paclitaxel resistance. ...Inhibiting PGAM1 may provide a new approach to favorably alter paclitaxel resistance in ovarian cancer....
Down-regulation of PGAM1 in SKOV3-TR30 cells resulted in decreased paclitaxel resistance. ...Inhibiting PGAM1 may provide a ne …
PGAM1 regulates the glycolytic metabolism of SCs in tibetan sheep and its influence on the development of SCs.
An X, Li T, Chen N, Wang H, Wang X, Ma Y. An X, et al. Gene. 2021 Dec 15;804:145897. doi: 10.1016/j.gene.2021.145897. Epub 2021 Aug 19. Gene. 2021. PMID: 34418471
This study was to explore the regulation effect of PGAM1 on the proliferation, apoptosis and glycolysis pathway of Tibetan sheep Sertoli cells. ...This result provides basic data for the study of the function of PGAM1 in sheep testicular development....
This study was to explore the regulation effect of PGAM1 on the proliferation, apoptosis and glycolysis pathway of Tibetan sheep Sert …
PGAM1 and TP53 mRNA levels in canine mammary carcinomas - Short communication.
Maués T, Oliveira TF, El-Jaick KB, Figueiredo AMS, Ferreira MLG, Ferreira AMR. Maués T, et al. Acta Vet Hung. 2021 Apr 10;69(1):50-54. doi: 10.1556/004.2021.00008. Acta Vet Hung. 2021. PMID: 33844639
TP53 and PGAM1 genes play a key role in glycolysis which is an essential metabolic pathway of cancer cells for obtaining energy. ...None of the nine samples analysed revealed PGAM1 DNA sequence variations. PGAM1 and TP53 RNA expressions from 21 CMC were analy …
TP53 and PGAM1 genes play a key role in glycolysis which is an essential metabolic pathway of cancer cells for obtaining energy. ...N …
PGAM1 knockdown is associated with busulfan-induced hypospermatogenesis and spermatogenic cell apoptosis.
Zhao Y, Zhang S. Zhao Y, et al. Mol Med Rep. 2019 Apr;19(4):2497-2502. doi: 10.3892/mmr.2019.9930. Epub 2019 Feb 4. Mol Med Rep. 2019. PMID: 30720109 Free PMC article.
Phosphoglycerate mutase 1 (PGAM1) is reported to be involved in spermatogenic dysfunction. However, the association between PGAM1 and busulfan-induced hypospermatogenesis and spermatogenic cell apoptosis remains unclear. The aim of the current study was to investiga …
Phosphoglycerate mutase 1 (PGAM1) is reported to be involved in spermatogenic dysfunction. However, the association between PGAM1 …
209 results