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1977 1
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1997 4
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2001 4
2003 1
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2006 2
2007 2
2008 1
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48 results

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Page 1
Phenylacetyl-/Trolox- Amides: Synthesis, Sigma-1, HDAC-6, and Antioxidant Activities.
Flores R, Iqbal S, Sikazwe D. Flores R, et al. Int J Mol Sci. 2023 Oct 18;24(20):15295. doi: 10.3390/ijms242015295. Int J Mol Sci. 2023. PMID: 37894975 Free PMC article.
Target compounds were conveniently synthesized via amidation by either directly reacting acyl chlorides with amines or condensing acids with amines in the presence of coupling agents 1-[bis(dimethylamino)methylene]-1H-1,2,3-triazolo [4,5-b] pyridinium 3-oxide hexafluoropho …
Target compounds were conveniently synthesized via amidation by either directly reacting acyl chlorides with amines or condensing aci …
Phentermine interference and high L-methamphetamine concentration problems in GC-EI-MS SIM Analyses of R-(-)-alpha-methoxy-alpha-(trifluoromethyl)phenylacetyl chloride-derivatized amphetamines and methamphetamines.
Hamilton TJ, Qui HZ, Dozier KV, Fuller ZJ. Hamilton TJ, et al. J Anal Toxicol. 2014 Sep;38(7):456-61. doi: 10.1093/jat/bku069. Epub 2014 Jun 20. J Anal Toxicol. 2014. PMID: 24951536
In order to achieve chromatographic separation, urine samples shown to be initially positive for amphetamines and methamphetamines in US Department of Defense immunoassays are derivatized with R-(-)-alpha-methoxy-alpha-(trifluoromethyl)phenylacetyl chloride (R-(-)-M …
In order to achieve chromatographic separation, urine samples shown to be initially positive for amphetamines and methamphetamines in US Dep …
Chiral separation of beta-blockers after derivatization with (-)-alphamethoxy-alpha-(trifluoromethyl)phenylacetyl chloride by gas chromatography.
Kim KH, Lee JH, Ko MY, Hong SP, Youm JR. Kim KH, et al. Arch Pharm Res. 2001 Oct;24(5):402-6. doi: 10.1007/BF02975183. Arch Pharm Res. 2001. PMID: 11693539
Gas chromatographic method was investigated for the chiral separation of several beta-blockers(atenolol, betaxolol, bisoprolol, metoprolol and pindolol) using (-)-alpha-methoxy-alpha-(trifluoromethyl)phenylacetyl chloride as a chiral derivatizing agent for amino gro …
Gas chromatographic method was investigated for the chiral separation of several beta-blockers(atenolol, betaxolol, bisoprolol, metoprolol a …
Detection of l-Methamphetamine and l-Amphetamine as Selegiline Metabolites.
Shin I, Choi H, Kang S, Kim J, Park Y, Yang W. Shin I, et al. J Anal Toxicol. 2021 Feb 6;45(1):99-104. doi: 10.1093/jat/bkaa058. J Anal Toxicol. 2021. PMID: 32476010
Furthermore, we confirmed l-methamphetamine and l-amphetamine by chiral derivatization using (R)-(-)-alpha-methoxy-alpha-(trifluoromethyl) phenylacetyl chloride....
Furthermore, we confirmed l-methamphetamine and l-amphetamine by chiral derivatization using (R)-(-)-alpha-methoxy-alpha-(trifluoromethyl) …
Stereochemistry of metabolism of amphetamines: use of (-)-alpha-methoxy-alpha-(trifluoromethyl)phenylacetyl chloride for GLC resolution of chiral amines.
Gal J. Gal J. J Pharm Sci. 1977 Feb;66(2):169-72. doi: 10.1002/jps.2600660209. J Pharm Sci. 1977. PMID: 839411
Amphetamine and eight related compounds were reacted with the chiral acylating reagent (-)-alpha-methoxy-alpha-(trifluoromethyl)phenylacetyl chloride to obtain, in each case, two diastereomeric amide derivatives. ...
Amphetamine and eight related compounds were reacted with the chiral acylating reagent (-)-alpha-methoxy-alpha-(trifluoromethyl)phenylace …
Enantiomeric profiling of amphetamines in wastewater using chiral derivatisation with gas chromatographic-tandem mass spectrometric detection.
Verovšek T, Heath D, Heath E. Verovšek T, et al. Sci Total Environ. 2022 Aug 20;835:155594. doi: 10.1016/j.scitotenv.2022.155594. Epub 2022 Apr 28. Sci Total Environ. 2022. PMID: 35490814 Free article.
We report on the enantiomeric profiling of amphetamines in wastewater using R(-)-alpha-methoxy-alpha-(trifluoromethyl) phenylacetyl chloride (R-MTPCl), a chiral derivatising agent and GC-MS/MS. ...
We report on the enantiomeric profiling of amphetamines in wastewater using R(-)-alpha-methoxy-alpha-(trifluoromethyl) phenylacetyl …
Mechanisms of solvolyses of acid chlorides and chloroformates. Chloroacetyl and phenylacetyl chloride as similarity models.
Bentley TW, Harris HC, Ryu ZH, Lim GT, Sung DD, Szajda SR. Bentley TW, et al. J Org Chem. 2005 Oct 28;70(22):8963-70. doi: 10.1021/jo0514366. J Org Chem. 2005. PMID: 16238334
[reaction: see text] Rate constants and product selectivities (S = ([ester product]/[acid product]) x ([water]/[alcohol solvent]) are reported for solvolyses of chloroacetyl chloride (3) at -10 degrees C and phenylacetyl chloride (4) at 0 degrees C in ethanol …
[reaction: see text] Rate constants and product selectivities (S = ([ester product]/[acid product]) x ([water]/[alcohol solvent]) are report …
Efficient construction of a β-naphthol library under continuous flow conditions.
Shan C, Li R, Wang X. Shan C, et al. RSC Adv. 2024 Jan 15;14(4):2673-2677. doi: 10.1039/d3ra08660g. eCollection 2024 Jan 10. RSC Adv. 2024. PMID: 38226147 Free PMC article.
A beta-naphthol library has been efficiently constructed utilizing a mild continuous flow procedure, relying on a tandem Friedel-Crafts reaction and starting from readily available arylacetyl chloride and alkynes. Multiple functionalized beta-naphthols can be acquired with …
A beta-naphthol library has been efficiently constructed utilizing a mild continuous flow procedure, relying on a tandem Friedel-Crafts reac …
Enantiomeric separation and quantitation of (+/-)-amphetamine, (+/-)-methamphetamine, (+/-)-MDA, (+/-)-MDMA, and (+/-)-MDEA in urine specimens by GC-EI-MS after derivatization with (R)-(-)- or (S)-(+)-alpha-methoxy-alpha-(trifluoromethy)phenylacetyl chloride (MTPA).
Paul BD, Jemionek J, Lesser D, Jacobs A, Searles DA. Paul BD, et al. J Anal Toxicol. 2004 Sep;28(6):449-55. doi: 10.1093/jat/28.6.449. J Anal Toxicol. 2004. PMID: 15516295
Instead of using TPC, we utilized (R)-(-)-alpha-methoxy-alpha-(trifluoromethyl)phenylacetyl chloride (MTPA) to prepare the amides of diastereomers of methamphetamine. ...The specimen concentrations (R + S) compared well with that of a non-chiral method that used 4-c …
Instead of using TPC, we utilized (R)-(-)-alpha-methoxy-alpha-(trifluoromethyl)phenylacetyl chloride (MTPA) to prepare the ami …
The Glutaminase-1 Inhibitor [11C-carbony]BPTES: Synthesis and Positron Emission Tomography Study in Mice.
Zhang Y, Kumata K, Xie L, Kurihara Y, Ogawa M, Kokufuta T, Nengaki N, Zhang MR. Zhang Y, et al. Pharmaceuticals (Basel). 2023 Jul 5;16(7):963. doi: 10.3390/ph16070963. Pharmaceuticals (Basel). 2023. PMID: 37513875 Free PMC article.
In this study, we synthesized [(11)C-carbonyl]BPTES ([(11)C]BPTES) as a positron emission tomography (PET) probe for the first time and assessed its biodistribution in mice using PET. [(11)C]BPTES was synthesized by the reaction of an amine precursor () with [(11)C-carbonyl]ph …
In this study, we synthesized [(11)C-carbonyl]BPTES ([(11)C]BPTES) as a positron emission tomography (PET) probe for the first time and asse …
48 results