Philippou H - Search Results

1

Fibrinogen αC-subregions critically contribute blood clot fibre growth, mechanical stability, and resistance to fibrinolysis.

McPherson HR, Duval C, Baker SR, Hindle MS, Cheah LT, Asquith NL, Domingues MM, Ridger VC, Connell SD, Naseem KM, Philippou H, Ajjan RA, Ariëns RA. McPherson HR, et al. Among authors: philippou h. Elife. 2021 Oct 11;10:e68761. doi: 10.7554/eLife.68761. Elife. 2021. PMID: 34633287 Free PMC article.

2

The factor XIII V34L polymorphism accelerates thrombin activation of factor XIII and affects cross-linked fibrin structure.

Ariëns RA, Philippou H, Nagaswami C, Weisel JW, Lane DA, Grant PJ. Ariëns RA, et al. Among authors: philippou h. Blood. 2000 Aug 1;96(3):988-95. Blood. 2000. PMID: 10910914 Free article.

3

Roles of low specificity and cofactor interaction sites on thrombin during factor XIII activation. Competition for cofactor sites on thrombin determines its fate.

Philippou H, Rance J, Myles T, Hall SW, Ariens RA, Grant PJ, Leung L, Lane DA. Philippou H, et al. J Biol Chem. 2003 Aug 22;278(34):32020-6. doi: 10.1074/jbc.M305364200. Epub 2003 Jun 6. J Biol Chem. 2003. PMID: 12794066 Free article.

4

Molecular mechanisms involved in the resistance of fibrin to clot lysis by plasmin in subjects with type 2 diabetes mellitus.

Dunn EJ, Philippou H, Ariëns RA, Grant PJ. Dunn EJ, et al. Among authors: philippou h. Diabetologia. 2006 May;49(5):1071-80. doi: 10.1007/s00125-006-0197-4. Epub 2006 Mar 16. Diabetologia. 2006. PMID: 16538489

5

Allele-specific alternative splicing; the tail of FXIII-B tells its own tale.

Uitte De Willige S, Philippou H, Ariëns RA. Uitte De Willige S, et al. Among authors: philippou h. J Thromb Haemost. 2009 Jul;7(7):1081-3. doi: 10.1111/j.1538-7836.2009.03479.x. Epub 2009 May 8. J Thromb Haemost. 2009. PMID: 19426285 Free article. No abstract available.

6

The pleiotropic role of the fibrinogen gamma' chain in hemostasis.

Uitte de Willige S, Standeven KF, Philippou H, Ariëns RA. Uitte de Willige S, et al. Among authors: philippou h. Blood. 2009 Nov 5;114(19):3994-4001. doi: 10.1182/blood-2009-05-217968. Epub 2009 Aug 17. Blood. 2009. PMID: 19687509 Free article. Review.

7

Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin.

Mutch NJ, Engel R, Uitte de Willige S, Philippou H, Ariëns RA. Mutch NJ, et al. Among authors: philippou h. Blood. 2010 May 13;115(19):3980-8. doi: 10.1182/blood-2009-11-254029. Epub 2010 Mar 12. Blood. 2010. PMID: 20228273 Free article.

8

Fibrin clot structure remains unaffected in young, healthy individuals after transient exposure to diesel exhaust.

Metassan S, Routledge MN, Lucking AJ, Uitte de Willige S, Philippou H, Mills NL, Newby DE, Ariëns RA. Metassan S, et al. Among authors: philippou h. Part Fibre Toxicol. 2010 Jun 16;7:17. doi: 10.1186/1743-8977-7-17. Part Fibre Toxicol. 2010. PMID: 20565709 Free PMC article.

9

Interactions between factor XIII and the alphaC region of fibrinogen.

Smith KA, Adamson PJ, Pease RJ, Brown JM, Balmforth AJ, Cordell PA, Ariëns RA, Philippou H, Grant PJ. Smith KA, et al. Among authors: philippou h. Blood. 2011 Mar 24;117(12):3460-8. doi: 10.1182/blood-2010-10-313601. Epub 2011 Jan 11. Blood. 2011. PMID: 21224475 Free article.

10

Proteolytic and genetic variation of the alpha-2-antiplasmin C-terminus in myocardial infarction.

Uitte de Willige S, Miedzak M, Carter AM, Lisman T, Rosendaal FR, Grant PJ, Philippou H, Ariëns RA. Uitte de Willige S, et al. Among authors: philippou h. Blood. 2011 Jun 16;117(24):6694-701. doi: 10.1182/blood-2010-11-320325. Epub 2011 Apr 19. Blood. 2011. PMID: 21505192 Free article.

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