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Ras signalling on the endoplasmic reticulum and the Golgi.
Chiu VK, Bivona T, Hach A, Sajous JB, Silletti J, Wiener H, Johnson RL 2nd, Cox AD, Philips MR. Chiu VK, et al. Among authors: philips mr. Nat Cell Biol. 2002 May;4(5):343-50. doi: 10.1038/ncb783. Nat Cell Biol. 2002. PMID: 11988737
PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis.
Bivona TG, Quatela SE, Bodemann BO, Ahearn IM, Soskis MJ, Mor A, Miura J, Wiener HH, Wright L, Saba SG, Yim D, Fein A, Pérez de Castro I, Li C, Thompson CB, Cox AD, Philips MR. Bivona TG, et al. Among authors: philips mr. Mol Cell. 2006 Feb 17;21(4):481-93. doi: 10.1016/j.molcel.2006.01.012. Mol Cell. 2006. PMID: 16483930 Free article.
FKBP12 binds to acylated H-ras and promotes depalmitoylation.
Ahearn IM, Tsai FD, Court H, Zhou M, Jennings BC, Ahmed M, Fehrenbacher N, Linder ME, Philips MR. Ahearn IM, et al. Among authors: philips mr. Mol Cell. 2011 Jan 21;41(2):173-85. doi: 10.1016/j.molcel.2011.01.001. Mol Cell. 2011. PMID: 21255728 Free PMC article.
Regulating the regulator: post-translational modification of RAS.
Ahearn IM, Haigis K, Bar-Sagi D, Philips MR. Ahearn IM, et al. Among authors: philips mr. Nat Rev Mol Cell Biol. 2011 Dec 22;13(1):39-51. doi: 10.1038/nrm3255. Nat Rev Mol Cell Biol. 2011. PMID: 22189424 Free PMC article. Review.
132 results