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Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase.
Aghajan M, Jonai N, Flick K, Fu F, Luo M, Cai X, Ouni I, Pierce N, Tang X, Lomenick B, Damoiseaux R, Hao R, Del Moral PM, Verma R, Li Y, Li C, Houk KN, Jung ME, Zheng N, Huang L, Deshaies RJ, Kaiser P, Huang J. Aghajan M, et al. Nat Biotechnol. 2010 Jul;28(7):738-42. doi: 10.1038/nbt.1645. Epub 2010 Jun 27. Nat Biotechnol. 2010. PMID: 20581845 Free PMC article.
Transfer of ubiquitin protein caught in the act.
Deshaies RJ, Pierce NW. Deshaies RJ, et al. Among authors: pierce nw. Nature. 2020 Feb;578(7795):372-373. doi: 10.1038/d41586-020-00325-9. Nature. 2020. PMID: 32066917 No abstract available.
Cilia grow by taking a bite out of the cell.
Pierce NW, Nachury MV. Pierce NW, et al. Dev Cell. 2013 Oct 28;27(2):126-127. doi: 10.1016/j.devcel.2013.10.013. Dev Cell. 2013. PMID: 24176638 Free PMC article.
Exome sequencing of Bardet-Biedl syndrome patient identifies a null mutation in the BBSome subunit BBIP1 (BBS18).
Scheidecker S, Etard C, Pierce NW, Geoffroy V, Schaefer E, Muller J, Chennen K, Flori E, Pelletier V, Poch O, Marion V, Stoetzel C, Strähle U, Nachury MV, Dollfus H. Scheidecker S, et al. Among authors: pierce nw. J Med Genet. 2014 Feb;51(2):132-6. doi: 10.1136/jmedgenet-2013-101785. Epub 2013 Sep 11. J Med Genet. 2014. PMID: 24026985 Free PMC article.