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A class of anti-inflammatory lipids decrease with aging in the central nervous system.
Tan D, Konduri S, Erikci Ertunc M, Zhang P, Wang J, Chang T, Pinto AFM, Rocha A, Donaldson CJ, Vaughan JM, Ludwig RG, Willey E, Iyer M, Gray PC, Maher P, Allen NJ, Zuchero JB, Dillin A, Mori MA, Kohama SG, Siegel D, Saghatelian A. Tan D, et al. Among authors: pinto afm. Nat Chem Biol. 2023 Feb;19(2):187-197. doi: 10.1038/s41589-022-01165-6. Epub 2022 Oct 20. Nat Chem Biol. 2023. PMID: 36266352 Free PMC article.
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice.
Erikci Ertunc M, Kok BP, Parsons WH, Wang JG, Tan D, Donaldson CJ, Pinto AFM, Vaughan JM, Ngo N, Lum KM, Henry CL, Coppola AR, Niphakis MJ, Cravatt BF, Saez E, Saghatelian A. Erikci Ertunc M, et al. Among authors: pinto afm. J Biol Chem. 2020 May 1;295(18):5891-5905. doi: 10.1074/jbc.RA119.012145. Epub 2020 Mar 9. J Biol Chem. 2020. PMID: 32152231 Free PMC article.
Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis.
Chen PB, Black AS, Sobel AL, Zhao Y, Mukherjee P, Molparia B, Moore NE, Aleman Muench GR, Wu J, Chen W, Pinto AFM, Maryanoff BE, Saghatelian A, Soroosh P, Torkamani A, Leman LJ, Ghadiri MR. Chen PB, et al. Among authors: pinto afm. Nat Biotechnol. 2020 Nov;38(11):1288-1297. doi: 10.1038/s41587-020-0549-5. Epub 2020 Jun 15. Nat Biotechnol. 2020. PMID: 32541956 Free PMC article.
FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis.
Becuwe M, Bond LM, Pinto AFM, Boland S, Mejhert N, Elliott SD, Cicconet M, Graham MM, Liu XN, Ilkayeva O, Saghatelian A, Walther TC, Farese RV Jr. Becuwe M, et al. Among authors: pinto afm. J Cell Biol. 2020 Oct 5;219(10):e202006111. doi: 10.1083/jcb.202006111. J Cell Biol. 2020. PMID: 32915949 Free PMC article.
Vitamin D Switches BAF Complexes to Protect β Cells.
Wei Z, Yoshihara E, He N, Hah N, Fan W, Pinto AFM, Huddy T, Wang Y, Ross B, Estepa G, Dai Y, Ding N, Sherman MH, Fang S, Zhao X, Liddle C, Atkins AR, Yu RT, Downes M, Evans RM. Wei Z, et al. Among authors: pinto afm. Cell. 2018 May 17;173(5):1135-1149.e15. doi: 10.1016/j.cell.2018.04.013. Epub 2018 May 10. Cell. 2018. PMID: 29754817 Free PMC article.
Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition.
Sander CL, Sears AE, Pinto AFM, Choi EH, Kahremany S, Gao F, Salom D, Jin H, Pardon E, Suh S, Dong Z, Steyaert J, Saghatelian A, Skowronska-Krawczyk D, Kiser PD, Palczewski K. Sander CL, et al. Among authors: pinto afm. J Cell Biol. 2021 Aug 2;220(8):e202101063. doi: 10.1083/jcb.202101063. Epub 2021 Jun 16. J Cell Biol. 2021. PMID: 34132745 Free PMC article.
Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD.
Garcia D, Hellberg K, Chaix A, Wallace M, Herzig S, Badur MG, Lin T, Shokhirev MN, Pinto AFM, Ross DS, Saghatelian A, Panda S, Dow LE, Metallo CM, Shaw RJ. Garcia D, et al. Among authors: pinto afm. Cell Rep. 2019 Jan 2;26(1):192-208.e6. doi: 10.1016/j.celrep.2018.12.036. Cell Rep. 2019. PMID: 30605676 Free PMC article.
The San Diego Nathan Shock Center: tackling the heterogeneity of aging.
Shadel GS, Adams PD, Berggren WT, Diedrich JK, Diffenderfer KE, Gage FH, Hah N, Hansen M, Hetzer MW, Molina AJA, Manor U, Marek K, O'Keefe DD, Pinto AFM, Sacco A, Sharpee TO, Shokriev MN, Zambetti S. Shadel GS, et al. Among authors: pinto afm. Geroscience. 2021 Oct;43(5):2139-2148. doi: 10.1007/s11357-021-00426-x. Epub 2021 Aug 9. Geroscience. 2021. PMID: 34370163 Free PMC article.
67 results