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CSF/plasma HIV-1 RNA discordance even at low levels is associated with up-regulation of host inflammatory mediators in CSF.
Nightingale S, Michael BD, Fisher M, Winston A, Nelson M, Taylor S, Ustianowski A, Ainsworth J, Gilson R, Haddow L, Ong E, Leen C, Minton J, Post F, Beloukas A, Borrow R, Pirmohamed M, Geretti AM, Khoo S, Solomon T. Nightingale S, et al. Among authors: pirmohamed m. Cytokine. 2016 Jul;83:139-146. doi: 10.1016/j.cyto.2016.04.004. Epub 2016 Apr 28. Cytokine. 2016. PMID: 27131579 Free PMC article. Clinical Trial.
Pharmacogenetics of HIV therapy.
Owen A, Pirmohamed M, Khoo SH, Back DJ. Owen A, et al. Among authors: pirmohamed m. Pharmacogenet Genomics. 2006 Oct;16(10):693-703. doi: 10.1097/01.fpc.0000236338.41799.57. Pharmacogenet Genomics. 2006. PMID: 17001288
Association of ABCC10 polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS.
Liptrott NJ, Pushpakom S, Wyen C, Fätkenheuer G, Hoffmann C, Mauss S, Knechten H, Brockmeyer NH, Hopper-Borge E, Siccardi M, Back DJ, Khoo SH, Pirmohamed M, Owen A; German Competence Network for HIV/AIDS. Liptrott NJ, et al. Among authors: pirmohamed m. Pharmacogenet Genomics. 2012 Jan;22(1):10-9. doi: 10.1097/FPC.0b013e32834dd82e. Pharmacogenet Genomics. 2012. PMID: 22082652 Free PMC article.
Population pharmacokinetic and pharmacogenetic analysis of nevirapine in hypersensitive and tolerant HIV-infected patients from Malawi.
Dickinson L, Chaponda M, Carr DF, van Oosterhout JJ, Kumwenda J, Lalloo DG, Pirmohamed M, Heyderman RS, Khoo SH. Dickinson L, et al. Among authors: pirmohamed m. Antimicrob Agents Chemother. 2014;58(2):706-12. doi: 10.1128/AAC.02069-13. Epub 2013 Nov 11. Antimicrob Agents Chemother. 2014. PMID: 24217698 Free PMC article.
CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan HIV populations.
Carr DF, Chaponda M, Cornejo Castro EM, Jorgensen AL, Khoo S, Van Oosterhout JJ, Dandara C, Kampira E, Ssali F, Munderi P, Lalloo DG, Heyderman RS, Pirmohamed M. Carr DF, et al. Among authors: pirmohamed m. J Antimicrob Chemother. 2014 Dec;69(12):3329-34. doi: 10.1093/jac/dku315. Epub 2014 Aug 20. J Antimicrob Chemother. 2014. PMID: 25147095 Free PMC article.
Telmisartan and Insulin Resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of telmisartan as a strategy for the reduction of insulin resistance in HIV-positive individuals on combination antiretroviral therapy.
Pushpakom SP, Taylor C, Kolamunnage-Dona R, Spowart C, Vora J, García-Fiñana M, Kemp GJ, Whitehead J, Jaki T, Khoo S, Williamson P, Pirmohamed M. Pushpakom SP, et al. Among authors: pirmohamed m. BMJ Open. 2015 Oct 15;5(10):e009566. doi: 10.1136/bmjopen-2015-009566. BMJ Open. 2015. PMID: 26474943 Free PMC article. Clinical Trial.
661 results