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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1951 4
1953 1
1954 1
1955 2
1956 3
1957 5
1958 3
1959 2
1961 1
1962 6
1963 11
1964 5
1965 3
1966 4
1967 2
1968 4
1969 3
1970 4
1971 3
1972 8
1973 7
1974 4
1975 4
1976 2
1977 24
1978 7
1979 6
1980 6
1981 15
1982 12
1983 19
1984 11
1985 5
1986 6
1987 10
1988 17
1989 8
1990 14
1991 18
1992 8
1993 16
1994 22
1995 12
1996 17
1997 21
1998 12
1999 15
2000 14
2001 22
2002 23
2003 22
2004 18
2005 21
2006 28
2007 38
2008 29
2009 37
2010 41
2011 42
2012 53
2013 55
2014 54
2015 89
2016 96
2017 92
2018 93
2019 121
2020 118
2021 117
2022 98
2023 98
2024 47

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1,682 results

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Page 1
Plat-E: an efficient and stable system for transient packaging of retroviruses.
Morita S, Kojima T, Kitamura T. Morita S, et al. Gene Ther. 2000 Jun;7(12):1063-6. doi: 10.1038/sj.gt.3301206. Gene Ther. 2000. PMID: 10871756
A potent retrovirus packaging cell line named Platinum-E (Plat-E) was generated based on the 293T cell line. Plat-E is superior to existing packaging cell lines regarding efficiency, stability and safety. ...Plat-E cells can stably produce retroviruses with a …
A potent retrovirus packaging cell line named Platinum-E (Plat-E) was generated based on the 293T cell line. Plat-E is superio …
Response to Plat and Mensink.
Calder PC, Rayman MP. Calder PC, et al. Br J Nutr. 2022 Apr 14;127(7):1119-1120. doi: 10.1017/S0007114521001793. Epub 2021 May 28. Br J Nutr. 2022. PMID: 34044897 No abstract available.
Thrombolysis by PLAT/tPA increases serum free IGF1 leading to a decrease of deleterious autophagy following brain ischemia.
Thiebaut AM, Buendia I, Ginet V, Lemarchand E, Boudjadja MB, Hommet Y, Lebouvier L, Lechevallier C, Maillasson M, Hedou E, Déglon N, Oury F, Rubio M, Montaner J, Puyal J, Vivien D, Roussel BD. Thiebaut AM, et al. Autophagy. 2022 Jun;18(6):1297-1317. doi: 10.1080/15548627.2021.1973339. Epub 2021 Sep 14. Autophagy. 2022. PMID: 34520334 Free PMC article.
In two in vitro models of hypoxia reperfusion and an in vivo model of thromboembolic stroke with thrombolysis by PLAT/tPA, we found that ischemia enhances neuronal deleterious autophagy. Interestingly, PLAT/tPA decreases autophagy to mediate neuroprotection by modul …
In two in vitro models of hypoxia reperfusion and an in vivo model of thromboembolic stroke with thrombolysis by PLAT/tPA, we found t …
Gene expression of PLAT and ATS3 proteins increases plant resistance to insects.
Savadogo EH, Shiomi Y, Yasuda J, Akino T, Yamaguchi M, Yoshida H, Umegawachi T, Tanaka R, Suong DNA, Miura K, Yazaki K, Kitajima S. Savadogo EH, et al. Planta. 2021 Jan 19;253(2):37. doi: 10.1007/s00425-020-03530-y. Planta. 2021. PMID: 33464406
Genes of the PLAT protein family, including PLAT and ATS3 subfamilies of higher plants and homologs of liverwort, are involved in plant defense against insects. ...In this study, we investigated whether the PLAT domain-containing proteins are involved in defe …
Genes of the PLAT protein family, including PLAT and ATS3 subfamilies of higher plants and homologs of liverwort, are involved …
Knockdown of PLAT enhances the anticancer effect of gefitinib in non-small cell lung cancer.
Yan M, Wang W, Zhou J, Chang M, Peng W, Zhang G, Li J, Li H, Bai C. Yan M, et al. J Thorac Dis. 2020 Mar;12(3):712-723. doi: 10.21037/jtd.2019.12.106. J Thorac Dis. 2020. PMID: 32274137 Free PMC article.
The aim of this study was to investigate the role of tissue-type plasminogen activator (PLAT) in gefitinib resistance in NSCLC. METHODS: The function of PLAT was determined using gefitinib-resistant cells and a nude mouse model. ...CONCLUSIONS: Our results suggest t …
The aim of this study was to investigate the role of tissue-type plasminogen activator (PLAT) in gefitinib resistance in NSCLC. METHO …
Low Expression of PLAT in Breast Cancer Infers Poor Prognosis and High Immune Infiltrating Level.
Wang X, Xue D, Zhu X, Geng R, Bao X, Chen X, Xia T. Wang X, et al. Int J Gen Med. 2021 Dec 22;14:10213-10224. doi: 10.2147/IJGM.S341959. eCollection 2021. Int J Gen Med. 2021. PMID: 35221711 Free PMC article.
We assessed the correlation between PLAT and immune infiltrating in breast cancer based on the TCGA database. ...DNA methylation of PLAT downregulates the gene expression and affects the prognosis of breast cancer. ...
We assessed the correlation between PLAT and immune infiltrating in breast cancer based on the TCGA database. ...DNA methylation of …
The Nodule-Specific PLAT Domain Protein NPD1 Is Required for Nitrogen-Fixing Symbiosis.
Pislariu CI, Sinharoy S, Torres-Jerez I, Nakashima J, Blancaflor EB, Udvardi MK. Pislariu CI, et al. Plant Physiol. 2019 Jul;180(3):1480-1497. doi: 10.1104/pp.18.01613. Epub 2019 May 6. Plant Physiol. 2019. PMID: 31061106 Free PMC article.
Previously, we isolated >100 nodulation and nitrogen fixation mutants from a population of Tnt1-insertion mutants of Medigaco truncatula Using Tnt1 as a tag to identify genetic lesions in these mutants, we discovered that insertions in a M. truncatula nodule-specific polycysti …
Previously, we isolated >100 nodulation and nitrogen fixation mutants from a population of Tnt1-insertion mutants of Medigaco truncatula …
Nodule-specific PLAT domain proteins are expanded in the Medicago lineage and required for nodulation.
Trujillo DI, Silverstein KAT, Young ND. Trujillo DI, et al. New Phytol. 2019 May;222(3):1538-1550. doi: 10.1111/nph.15697. Epub 2019 Feb 27. New Phytol. 2019. PMID: 30664233 Free article.
In the Medicago lineage, nodule-specific Polycystin-1, Lipoxygenase, Alpha Toxin (PLAT) domain proteins (NPDs) expanded to five members. We examined NPD function using CRISPR/Cas9 multiplex genome editing to create Medicago truncatula NPD knockout lines, targeting one to f …
In the Medicago lineage, nodule-specific Polycystin-1, Lipoxygenase, Alpha Toxin (PLAT) domain proteins (NPDs) expanded to five membe …
DNA Methylation of Proximal PLAT Promoter in Chronic Rhinosinusitis With Nasal Polyps.
Kidoguchi M, Noguchi E, Nakamura T, Ninomiya T, Morii W, Yoshida K, Morikawa T, Kato Y, Imoto Y, Sakashita M, Takabayashi T, Fujieda S. Kidoguchi M, et al. Am J Rhinol Allergy. 2018 Sep;32(5):374-379. doi: 10.1177/1945892418782236. Epub 2018 Jul 2. Am J Rhinol Allergy. 2018. PMID: 29962211
The epigenetic mechanism regulating the PLAT gene expression has been studied in other tissues. Objective We aimed to investigate the methylation levels in the proximal PLAT promoter and their effects on gene expression in NP tissue. ...DNA methylation of proximal …
The epigenetic mechanism regulating the PLAT gene expression has been studied in other tissues. Objective We aimed to investigate the …
Early application of airway pressure release ventilation may reduce the duration of mechanical ventilation in acute respiratory distress syndrome.
Zhou Y, Jin X, Lv Y, Wang P, Yang Y, Liang G, Wang B, Kang Y. Zhou Y, et al. Intensive Care Med. 2017 Nov;43(11):1648-1659. doi: 10.1007/s00134-017-4912-z. Epub 2017 Sep 22. Intensive Care Med. 2017. PMID: 28936695 Free PMC article.
The settings for LTV were: target tidal volume of 6 mL/kg of predicted body weight; P(plat) not exceeding 30 cmH(2)O; positive end-expiratory pressure (PEEP) guided by the PEEP-FiO(2) table according to the ARDSnet protocol. ...CONCLUSIONS: Compared with LTV, early applica …
The settings for LTV were: target tidal volume of 6 mL/kg of predicted body weight; P(plat) not exceeding 30 cmH(2)O; positive end-ex …
1,682 results