Plate R - Search Results

1

Synthesis, and in vitro and in vivo muscarinic pharmacological properties of a series of 1,6-dihydro-5-(4H)-pyrimidinone oximes.

Plate R, Plaum MJ, Pintar P, Jans CG, de Boer T, Dijcks FA, Ruigt G, Andrews JS. Plate R, et al. Bioorg Med Chem. 1998 Sep;6(9):1404-20. doi: 10.1016/s0968-0896(98)00074-1. Bioorg Med Chem. 1998. PMID: 9801812

2

Synthesis and muscarinic activities of 3-(pyrazolyl)-1,2,5,6-tetrahydropyridine derivatives.

Plate R, Plaum MJ, de Boer T, Andrews JS, Rae DR, Gibson S. Plate R, et al. Bioorg Med Chem. 1996 Feb;4(2):227-37. doi: 10.1016/0968-0896(96)00001-6. Bioorg Med Chem. 1996. PMID: 8814880

3

Synthesis and muscarinic M3 pharmacological activities of 1-azabicyclo[2.2.2]octan-3-one oxime derivatives.

Plate R, Plaum MJ, de Boer T, Andrews JS. Plate R, et al. Bioorg Med Chem. 1996 Feb;4(2):239-45. doi: 10.1016/0968-0896(96)00035-1. Bioorg Med Chem. 1996. PMID: 8814881

4

Synthesis and in vitro muscarinic activities of a series of 3-(pyrazol-3-yl)-1-azabicyclo[2.2.2]octanes.

Plate R, Plaum MJ, van der Hulst RG, de Boer T. Plate R, et al. Bioorg Med Chem. 2000 Feb;8(2):449-54. doi: 10.1016/s0968-0896(99)00299-0. Bioorg Med Chem. 2000. PMID: 10722168

5

Synthesis and in vitro muscarinic activities of a series of 1,3-diazacycloalkyl carboxaldehyde oxime derivatives.

Plate R, Jans CG, Plaum MJ, de Boer T. Plate R, et al. Bioorg Med Chem. 2002 Apr;10(4):1143-52. doi: 10.1016/s0968-0896(01)00379-0. Bioorg Med Chem. 2002. PMID: 11836126

6

Synthesis of (3alpha,7beta, 17alpha)-7-methyl-19-norpregn-5(10)-en-20-yne-3,7,17-triol, a metabolite of ORG OD14, and its 7-epimer.

Plate R, van Wuijtswinkel RC, Jans CG, Groen MB. Plate R, et al. Steroids. 2000 Sep;65(9):497-504. doi: 10.1016/s0039-128x(00)00110-0. Steroids. 2000. PMID: 10978728 Corrected and republished.

7

Synthesis of (3alpha,7beta,17alpha)-7-methyl-19-norpregn-5(10)-en-20-yne-3,7,17-triol, a metabolite of ORG OD14, and its 7-epimer.

Plate R, van Wuijtswinkel RC, Jans CG, Groen MB. Plate R, et al. Steroids. 2001 Feb;66(2):117-26. doi: 10.1016/s0039-128x(00)00233-6. Steroids. 2001. PMID: 11146092

8

Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index.

van Lierop MJ, Alkema W, Laskewitz AJ, Dijkema R, van der Maaden HM, Smit MJ, Plate R, Conti PG, Jans CG, Timmers CM, van Boeckel CA, Lusher SJ, McGuire R, van Schaik RC, de Vlieg J, Smeets RL, Hofstra CL, Boots AM, van Duin M, Ingelse BA, Schoonen WG, Grefhorst A, van Dijk TH, Kuipers F, Dokter WH. van Lierop MJ, et al. Among authors: plate r. PLoS One. 2012;7(11):e48385. doi: 10.1371/journal.pone.0048385. Epub 2012 Nov 12. PLoS One. 2012. PMID: 23152771 Free PMC article.

9

Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2).

Roumen L, Peeters JW, Emmen JM, Beugels IP, Custers EM, de Gooyer M, Plate R, Pieterse K, Hilbers PA, Smits JF, Vekemans JA, Leysen D, Ottenheijm HC, Janssen HM, Hermans JJ. Roumen L, et al. Among authors: plate r. J Med Chem. 2010 Feb 25;53(4):1712-25. doi: 10.1021/jm901356d. J Med Chem. 2010. PMID: 20121113

10

Mechanism of action of a nanomolar potent, allosteric antagonist of the thyroid-stimulating hormone receptor.

van Koppen CJ, de Gooyer ME, Karstens WJ, Plate R, Conti PG, van Achterberg TA, van Amstel MG, Brands JH, Wat J, Berg RJ, Lane JR, Miltenburg AM, Timmers CM. van Koppen CJ, et al. Among authors: plate r. Br J Pharmacol. 2012 Apr;165(7):2314-24. doi: 10.1111/j.1476-5381.2011.01709.x. Br J Pharmacol. 2012. PMID: 22014107 Free PMC article.

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