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Polar, functionalized guanine-O6 derivatives resistant to repair by O6-alkylguanine-DNA alkyltransferase: implications for the design of DNA-modifying drugs.
Eur J Med Chem. 2006 Mar;41(3):330-9. doi: 10.1016/j.ejmech.2005.11.007. Epub 2006 Feb 3.
Eur J Med Chem. 2006.
PMID: 16458393
Design, synthesis, and evaluation of novel biarylpyrimidines: a new class of ligand for unusual nucleic acid structures.
Wheelhouse RT, Jennings SA, Phillips VA, Pletsas D, Murphy PM, Garbett NC, Chaires JB, Jenkins TC.
Wheelhouse RT, et al. Among authors: pletsas d.
J Med Chem. 2006 Aug 24;49(17):5187-98. doi: 10.1021/jm060315a.
J Med Chem. 2006.
PMID: 16913707
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Synthesis and quantitative structure-activity relationship of imidazotetrazine prodrugs with activity independent of O6-methylguanine-DNA-methyltransferase, DNA mismatch repair, and p53.
Pletsas D, Garelnabi EA, Li L, Phillips RM, Wheelhouse RT.
Pletsas D, et al.
J Med Chem. 2013 Sep 12;56(17):7120-32. doi: 10.1021/jm401121k. Epub 2013 Aug 16.
J Med Chem. 2013.
PMID: 23895620
Free PMC article.
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Strategy for Imidazotetrazine Prodrugs with Anticancer Activity Independent of MGMT and MMR.
Garelnabi EA, Pletsas D, Li L, Kiakos K, Karodia N, Hartley JA, Phillips RM, Wheelhouse RT.
Garelnabi EA, et al. Among authors: pletsas d.
ACS Med Chem Lett. 2012 Sep 18;3(12):965-8. doi: 10.1021/ml300132t. eCollection 2012 Dec 13.
ACS Med Chem Lett. 2012.
PMID: 24900418
Free PMC article.
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Methods to Reduce Energy and Polymer Consumption for Fused Filament Fabrication 3D Printing.
Harding OJ, Griffiths CA, Rees A, Pletsas D.
Harding OJ, et al. Among authors: pletsas d.
Polymers (Basel). 2023 Apr 13;15(8):1874. doi: 10.3390/polym15081874.
Polymers (Basel). 2023.
PMID: 37112021
Free PMC article.
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