Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2000 2
2001 1
2002 9
2003 9
2004 10
2005 9
2006 5
2007 14
2008 11
2009 16
2010 16
2011 14
2012 11
2013 15
2014 15
2015 16
2016 13
2017 16
2018 12
2019 12
2020 9
2021 9
2022 12
2023 6
2024 5

Text availability

Article attribute

Article type

Publication date

Search Results

227 results

Results by year

Filters applied: . Clear all
Page 1
Barcoded viral tracing of single-cell interactions in central nervous system inflammation.
Clark IC, Gutiérrez-Vázquez C, Wheeler MA, Li Z, Rothhammer V, Linnerbauer M, Sanmarco LM, Guo L, Blain M, Zandee SEJ, Chao CC, Batterman KV, Schwabenland M, Lotfy P, Tejeda-Velarde A, Hewson P, Manganeli Polonio C, Shultis MW, Salem Y, Tjon EC, Fonseca-Castro PH, Borucki DM, Alves de Lima K, Plasencia A, Abate AR, Rosene DL, Hodgetts KJ, Prinz M, Antel JP, Prat A, Quintana FJ. Clark IC, et al. Science. 2021 Apr 23;372(6540):eabf1230. doi: 10.1126/science.abf1230. Science. 2021. PMID: 33888612 Free PMC article.
PLXNB1 mutations in the etiology of idiopathic hypogonadotropic hypogonadism.
Welch BA, Cho HJ, Ucakturk SA, Farmer SM, Cetinkaya S, Abaci A, Akkus G, Simsek E, Kotan LD, Turan I, Gurbuz F, Yuksel B, Wray S, Topaloglu AK. Welch BA, et al. J Neuroendocrinol. 2022 Apr;34(4):e13103. doi: 10.1111/jne.13103. Epub 2022 Feb 16. J Neuroendocrinol. 2022. PMID: 35170806
In total, 336 IHH patients (normosmic IHH, n = 293 and Kallmann syndrome, n = 43) from 290 independent families were included in the present study. Six PLXNB1 rare sequence variants (p.N361S, p.V608A, p.R636C, p.V672A, p.R1031H, and p.C1318R) are described in eight normosm …
In total, 336 IHH patients (normosmic IHH, n = 293 and Kallmann syndrome, n = 43) from 290 independent families were included in the present …
Neurite outgrowth deficits caused by rare PLXNB1 mutation in pediatric bipolar disorder.
Yang G, Ullah HMA, Parker E, Gorsi B, Libowitz M, Maguire C, King JB, Coon H, Lopez-Larson M, Anderson JS, Yandell M, Shcheglovitov A. Yang G, et al. Mol Psychiatry. 2023 Jun;28(6):2525-2539. doi: 10.1038/s41380-023-02035-w. Epub 2023 Apr 10. Mol Psychiatry. 2023. PMID: 37032361
Expression of wild-type PLXNB1, but not the variant, rescued neurite outgrowth in patient neurons, and expression of the variant caused the neurite outgrowth deficits in cortical neurons from PlxnB1 knockout mice. These results indicate that dysregulated PLXNB1 …
Expression of wild-type PLXNB1, but not the variant, rescued neurite outgrowth in patient neurons, and expression of the variant caus …
MiR-362-5p inhibits cartilage repair in osteoarthritis via targeting plexin B1.
Li Q, Xu P, Zhang C, Gao Y. Li Q, et al. J Orthop Surg (Hong Kong). 2022 Sep-Dec;30(3):10225536221139887. doi: 10.1177/10225536221139887. J Orthop Surg (Hong Kong). 2022. PMID: 36523183 Free article.
Mechanically, PLXNB1 was targeted by miR-362-5p. In rescue assays, miR-362-5p reversed the effects of PLXNB1 on chondrogenic differentiation of BMSCs. ...CONCLUSION: MiR-362-5p promotes OA progression by suppressing PLXNB1....
Mechanically, PLXNB1 was targeted by miR-362-5p. In rescue assays, miR-362-5p reversed the effects of PLXNB1 on chondrogenic d …
Increased BMSC exosomal miR-140-3p alleviates bone degradation and promotes bone restoration by targeting Plxnb1 in diabetic rats.
Wang N, Liu X, Tang Z, Wei X, Dong H, Liu Y, Wu H, Wu Z, Li X, Ma X, Guo Z. Wang N, et al. J Nanobiotechnology. 2022 Mar 2;20(1):97. doi: 10.1186/s12951-022-01267-2. J Nanobiotechnology. 2022. PMID: 35236339 Free PMC article.
In in vitro experiments, upregulated miR-140-3p exosomes promoted DM BMSCs differentiation into osteoblasts. The effects were exerted by miR-140-3p targeting plxnb1, plexin B1 is the receptor of semaphoring 4D(Sema4D) that inhibited osteocytes differentiation, thereby prom …
In in vitro experiments, upregulated miR-140-3p exosomes promoted DM BMSCs differentiation into osteoblasts. The effects were exerted by miR …
Long noncoding RNA ZEB2-AS1 facilitates laryngeal squamous cell carcinoma progression by miR-6840-3p/PLXNB1 axis.
Xu Q, Liu H, Yu B, Chen W, Zhai L, Li X, Fang Y. Xu Q, et al. Onco Targets Ther. 2019 Sep 6;12:7337-7345. doi: 10.2147/OTT.S212749. eCollection 2019. Onco Targets Ther. 2019. PMID: 31564916 Free PMC article.
We identified that ZEB2-AS1 binds to miR-6840-3p and targets PLXNB1. Additionally, miR-6840-3p overexpression or knockdown of PLXNB1 decreased the abilities of cell migration and invasion. CONCLUSION: These findings demonstrated that overexpression of ZEB2-AS1 promo …
We identified that ZEB2-AS1 binds to miR-6840-3p and targets PLXNB1. Additionally, miR-6840-3p overexpression or knockdown of PLXN …
De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function.
Sugano-Nakamura N, Matoba K, Hirose M, Bashiruddin NK, Matsunaga Y, Yamashita K, Hirata K, Yamamoto M, Arimori T, Suga H, Takagi J. Sugano-Nakamura N, et al. Structure. 2022 Oct 6;30(10):1411-1423.e4. doi: 10.1016/j.str.2022.07.008. Epub 2022 Aug 17. Structure. 2022. PMID: 35981535 Free article.
Here, we describe the generation of both antagonistic and agonistic receptor dimerizers toward PlexinB1 (PlxnB1), a receptor for semaphorin 4D (Sema4D), by grafting two different PlxnB1-binding peptides onto the human immunoglobulin G1 (IgG1) Fc protein. The functio …
Here, we describe the generation of both antagonistic and agonistic receptor dimerizers toward PlexinB1 (PlxnB1), a receptor for sema …
Circular RNA circ_0065378 upregulates tumor suppressor candidate 1 by competitively binding with miR-4701-5p to alleviate colorectal cancer progression.
Yan D, Liu W, Liu Y, Zhu X. Yan D, et al. J Gastroenterol Hepatol. 2022 Jun;37(6):1107-1118. doi: 10.1111/jgh.15862. Epub 2022 May 1. J Gastroenterol Hepatol. 2022. PMID: 35434854
Mouse xenograft models were used to investigate the role of circ_PLXNB1 in tumor growth. RESULTS: The results showed that gene expression of circ_PLXNB1 in CRC tissues was significantly downregulated. ...Mechanistically, circ_PLXNB1 exerted its functional eff …
Mouse xenograft models were used to investigate the role of circ_PLXNB1 in tumor growth. RESULTS: The results showed that gene expres …
The emerging roles of semaphorin4D/CD100 in immunological diseases.
Wang L, Li X, Song Y, Song D, Huang D. Wang L, et al. Biochem Soc Trans. 2020 Dec 18;48(6):2875-2890. doi: 10.1042/BST20200821. Biochem Soc Trans. 2020. PMID: 33258873 Review.
SEMA4D has diverse effects on immunologic processes, including immune cell proliferation, differentiation, activation, and migration, through binding to its specific membrane receptors CD72, PLXNB1, and PLXNB2. Furthermore, SEMA4D and its underlying signaling have been inc …
SEMA4D has diverse effects on immunologic processes, including immune cell proliferation, differentiation, activation, and migration, throug …
227 results