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2003 1
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2014 1
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22 results

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miR-624 accelerates the growth of liver cancer cells by inhibiting EMC3.
Jiang X, Lu Y, Xie S, Chen Y, Liu X, Li S, Song S, Wang L, Lu D. Jiang X, et al. Noncoding RNA Res. 2023 Sep 24;8(4):641-644. doi: 10.1016/j.ncrna.2023.09.005. eCollection 2023 Dec. Noncoding RNA Res. 2023. PMID: 37810370 Free PMC article.
On the other hand, miR-624 affects proteome of several genes in liver cancer, such as, RBM5,PTK2, KDM2A,POLR2H, POLR2G,CDK6,KIF15,CUL2,FKBP2,ErbB-3,JUN, PKM2, CyclinE,PLK1, mTOR, PPARgamma, Rab7A,ARAF, UPF3B ,PTEN, SUZ12, GADD45, H3.3, CUL5, ARF6,EMC3,ATG4B,ATG14,CALR. ...
On the other hand, miR-624 affects proteome of several genes in liver cancer, such as, RBM5,PTK2, KDM2A,POLR2H, POLR2G,CDK6,KIF15,CUL …
RNA polymerase II subunit D is essential for zebrafish development.
Maeta M, Kataoka M, Nishiya Y, Ogino K, Kashima M, Hirata H. Maeta M, et al. Sci Rep. 2020 Aug 6;10(1):13213. doi: 10.1038/s41598-020-70110-1. Sci Rep. 2020. PMID: 32764610 Free PMC article.
The dissociable subcomplex is a heterodimer of Rpb4/Polr2d and Rpb7/Polr2g, which are encoded by RPB4/polr2d and RPB7/polr2g genes, respectively. ...
The dissociable subcomplex is a heterodimer of Rpb4/Polr2d and Rpb7/Polr2g, which are encoded by RPB4/polr2d and RPB7/polr2g g …
Comprehensive Analysis of Gene Expression Profiles and DNA Methylome reveals Oas1, Ppie, Polr2g as Pathogenic Target Genes of Gestational Diabetes Mellitus.
Zhang Y, Zhang T, Chen Y. Zhang Y, et al. Sci Rep. 2018 Nov 2;8(1):16244. doi: 10.1038/s41598-018-34292-z. Sci Rep. 2018. PMID: 30389953 Free PMC article.
GO (gene ontology) and KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway analysis of 326 overlapping genes between DMGs and DEGs showed obvious enrichment in terms related to metabolic disorders and immune responses. We identified Oas1, Ppie, Polr2g as possible pathog …
GO (gene ontology) and KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway analysis of 326 overlapping genes between DMGs and DEGs showed …
miR-34a-5p as molecular hub of pathomechanisms in Huntington's disease.
Hart M, Diener C, Lunkes L, Rheinheimer S, Krammes L, Keller A, Meese E. Hart M, et al. Mol Med. 2023 Apr 3;29(1):43. doi: 10.1186/s10020-023-00640-7. Mol Med. 2023. PMID: 37013480 Free PMC article.
RESULTS: Using our high-throughput miRNA interaction reporter assay (HiTmIR) we identified NDUFA9, TAF4B, NRF1, POLR2J2, DNALI1, HIP1, TGM2 and POLR2G as direct miR-34a-5p target genes. Direct binding of miR-34a-5p to target sites in the 3'UTRs of TAF4B, NDUFA9, HIP1 and N …
RESULTS: Using our high-throughput miRNA interaction reporter assay (HiTmIR) we identified NDUFA9, TAF4B, NRF1, POLR2J2, DNALI1, HIP1, TGM2 …
Specific expression network analysis of diabetic nephropathy kidney tissue revealed key methylated sites.
Wang YZ, Xu WW, Zhu DY, Zhang N, Wang YL, Ding M, Xie XM, Sun LL, Wang XX. Wang YZ, et al. J Cell Physiol. 2018 Oct;233(10):7139-7147. doi: 10.1002/jcp.26638. Epub 2018 May 8. J Cell Physiol. 2018. PMID: 29737531
Besides, we also identified 1 up-regulated gene (PIK3C2B) and 39 down-regulated genes (POLR2G, DDB1, and ZNF230, etc.) in the methylated data of Glom specific genes. ...
Besides, we also identified 1 up-regulated gene (PIK3C2B) and 39 down-regulated genes (POLR2G, DDB1, and ZNF230, etc.) in the methyla …
Single-Cell RNA Sequencing Reveals the Role of Phosphorylation-Related Genes in Hepatocellular Carcinoma Stem Cells.
Yao F, Zhan Y, Li C, Lu Y, Chen J, Deng J, Wu Z, Li Q, Song Y, Chen B, Chen J, Tian K, Pu Z, Ni Y, Mou L. Yao F, et al. Front Cell Dev Biol. 2022 Jan 4;9:734287. doi: 10.3389/fcell.2021.734287. eCollection 2021. Front Cell Dev Biol. 2022. PMID: 35059393 Free PMC article.
We found nine protein kinases and PRGs with high expression levels that were mainly detected in HCC cancer stem cells, including POLR2G, PPP2R1A, POLR2L, PRC1, ITBG1BP1, MARCKSL1, EZH2, DTYMK, and AURKA. ...
We found nine protein kinases and PRGs with high expression levels that were mainly detected in HCC cancer stem cells, including POLR2G
Identification of a novel DNA repair-related prognostic signature predicting survival of patients with hepatocellular carcinoma.
Li N, Zhao L, Guo C, Liu C, Liu Y. Li N, et al. Cancer Manag Res. 2019 Aug 6;11:7473-7484. doi: 10.2147/CMAR.S204864. eCollection 2019. Cancer Manag Res. 2019. PMID: 31496805 Free PMC article.
RESULTS: GSEA revealed that the hallmark DNA repair gene set was significantly upregulated in the tumor phenotype. A set of seven genes, namely, ADA, FEN1, POLR2G, SAC3D1, SEC61A1, SF3A3, and UPF3B, were significantly a ssociated with overall survival (OS) and used to form …
RESULTS: GSEA revealed that the hallmark DNA repair gene set was significantly upregulated in the tumor phenotype. A set of seven genes, nam …
A novel approach to genome-wide association analysis identifies genetic associations with primary biliary cholangitis and primary sclerosing cholangitis in Polish patients.
Paziewska A, Habior A, Rogowska A, Zych W, Goryca K, Karczmarski J, Dabrowska M, Ambrozkiewicz F, Walewska-Zielecka B, Krawczyk M, Cichoz-Lach H, Milkiewicz P, Kowalik A, Mucha K, Raczynska J, Musialik J, Boryczka G, Wasilewicz M, Ciecko-Michalska I, Ferenc M, Janiak M, Kanikowska A, Stankiewicz R, Hartleb M, Mach T, Grzymislawski M, Raszeja-Wyszomirska J, Wunsch E, Bobinski T, Mikula M, Ostrowski J. Paziewska A, et al. BMC Med Genomics. 2017 Jan 6;10(1):2. doi: 10.1186/s12920-016-0239-9. BMC Med Genomics. 2017. PMID: 28056976 Free PMC article.
The SNPs mapped to seven (1p31.3, 3q13, 6p21, 7q32.1, 11q23.3, 17q12, 19q13.33) and one (6p21) chromosome region previously associated with PBC and PSC, respectively. The SNP, rs35730843, mapping to the POLR2G gene promoter (P = 1.2 10(-5), OR = 0.39) demonstrated the high …
The SNPs mapped to seven (1p31.3, 3q13, 6p21, 7q32.1, 11q23.3, 17q12, 19q13.33) and one (6p21) chromosome region previously associated with …
Mining the role of RECQL5 in gastric cancer and seeking potential regulatory network by bioinformatics analysis.
Lin Y, Chen H, Wang X, Xiang J, Wang H, Peng J. Lin Y, et al. Exp Mol Pathol. 2020 Aug;115:104477. doi: 10.1016/j.yexmp.2020.104477. Epub 2020 Jun 1. Exp Mol Pathol. 2020. PMID: 32497619
RECQL5 might be enriched in homologous recombination pathways and Fanconi anemia pathway. Bioinformatics analysis identified 5 genes, namely POLR2D, POLR2G, DXO, KIN, and EIF2D, that were significantly correlated with RECQL5. ...
RECQL5 might be enriched in homologous recombination pathways and Fanconi anemia pathway. Bioinformatics analysis identified 5 genes, namely …
Genome and chromosome wide association studies for growth traits in Simmental and Simbrah cattle.
Calderón-Chagoya R, Vega-Murillo VE, García-Ruiz A, Ríos-Utrera Á, Martínez-Velázquez G, Montaño-Bermúdez M. Calderón-Chagoya R, et al. Anim Biosci. 2023 Jan;36(1):19-28. doi: 10.5713/ab.21.0517. Epub 2022 Jun 30. Anim Biosci. 2023. PMID: 35798032 Free PMC article.
It stands out from the enrichment analysis of the pathways for RNA polymerase (POLR2G, POLR3E) and GABAergic synapse (GABRR1, GABRR3) for Simmental cattle and p53 signaling pathway (BID, SERPINB5) for Simbrah cattle. ...
It stands out from the enrichment analysis of the pathways for RNA polymerase (POLR2G, POLR3E) and GABAergic synapse (GABRR1, GABRR3) …
22 results