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Year Number of Results
1799 1
1850 2
1945 1
1947 1
1949 1
1952 1
1954 1
1955 1
1964 1
1965 1
1966 1
1967 1
1968 1
1974 1
1975 1
1976 1
1977 3
1981 1
1982 1
1983 1
1984 1
1985 2
1989 2
1990 1
1991 1
1992 1
1993 4
1994 10
1995 8
1996 6
1997 6
1998 4
1999 6
2000 12
2001 2
2002 7
2003 10
2004 14
2005 13
2006 25
2007 22
2008 20
2009 27
2010 21
2011 34
2012 41
2013 24
2014 35
2015 38
2016 39
2017 36
2018 31
2019 26
2020 39
2021 48
2022 46
2023 35
2024 24

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662 results

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The following term was not found in PubMed: munbyana
Page 1
Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy.
Qiu WQ, Ai W, Zhu FD, Zhang Y, Guo MS, Law BY, Wu JM, Wong VK, Tang Y, Yu L, Chen Q, Yu CL, Liu J, Qin DL, Zhou XG, Wu AG. Qiu WQ, et al. Free Radic Biol Med. 2022 Feb 1;179:76-94. doi: 10.1016/j.freeradbiomed.2021.12.263. Epub 2021 Dec 20. Free Radic Biol Med. 2022. PMID: 34933095 Review.
In this study, we investigated whether triterpenoid saponins in Radix Polygalae inhibit the NLRP3 inflammasome via mitophagy induction. First, we isolated the active fraction (polygala saponins (PSS)) and identified 17 saponins by ultra-performance liquid chromatogr …
In this study, we investigated whether triterpenoid saponins in Radix Polygalae inhibit the NLRP3 inflammasome via mitophagy inductio …
Therapeutic potential of Polygala saponins in neurological diseases.
Zhang L, Yong YY, Deng L, Wang J, Law BY, Hu ML, Wu JM, Yu L, Wong VK, Yu CL, Qin DL, Zhou XG, Wu AG. Zhang L, et al. Phytomedicine. 2023 Jan;108:154483. doi: 10.1016/j.phymed.2022.154483. Epub 2022 Sep 29. Phytomedicine. 2023. PMID: 36260972 Review.
RESULTS: This literature review mainly reports on the traditional use of the Polygala genus and prescriptions containing Radix Polygalae in neurological diseases. ...This review provides directions for the future study of Polygala saponins and references for …
RESULTS: This literature review mainly reports on the traditional use of the Polygala genus and prescriptions containing Radix Pol …
Polygala tenuifolia: a source for anti-Alzheimer's disease drugs.
Deng X, Zhao S, Liu X, Han L, Wang R, Hao H, Jiao Y, Han S, Bai C. Deng X, et al. Pharm Biol. 2020 Dec;58(1):410-416. doi: 10.1080/13880209.2020.1758732. Pharm Biol. 2020. PMID: 32429787 Free PMC article. Review.
However, lacking effective drugs is the biggest handicap in treating AD. In traditional Chinese medicine (TCM), Polygala tenuifolia Willd. (Polygalaceae) is generally used to treat insomnia, memory dysfunction and neurasthenia.Objective: This review article explores the ro …
However, lacking effective drugs is the biggest handicap in treating AD. In traditional Chinese medicine (TCM), Polygala tenuifolia W …
Aqueous extract of Polygala japonica Houtt. ameliorated nonalcoholic steatohepatitis in mice through restoring the gut microbiota disorders and affecting the metabolites in feces and liver.
Liao J, Cao Y, Zhao J, Yu B, Wang Y, Li W, Li H, Lv S, Wen W, Cui H, Chen Y. Liao J, et al. Phytomedicine. 2023 Sep;118:154937. doi: 10.1016/j.phymed.2023.154937. Epub 2023 Jun 20. Phytomedicine. 2023. PMID: 37393831
BACKGROUND: Polygala japonica Houtt. (PJ) has been demonstrated with several biological potentials such as lipid-lowering and anti-inflammatory effects. ...
BACKGROUND: Polygala japonica Houtt. (PJ) has been demonstrated with several biological potentials such as lipid-lowering and anti-in …
Polysaccharide from Polygala tenuifolia alleviates cognitive decline in Alzheimer's disease mice by alleviating Abeta damage and targeting the ERK pathway.
Li Y, Wu H, Liu M, Zhang Z, Ji Y, Xu L, Liu Y. Li Y, et al. J Ethnopharmacol. 2024 Mar 1;321:117564. doi: 10.1016/j.jep.2023.117564. Epub 2023 Dec 9. J Ethnopharmacol. 2024. PMID: 38081400
ETHNOPHARMACOLOGICAL RELEVANCE: Polygala tenuifolia is used in a variety of Chinese medicine prescriptions for the classic dementia treatment, and polysaccharide is an important active component in the herb. AIM OF THE STUDY: This study investigated the in vivo anti-Alzhei …
ETHNOPHARMACOLOGICAL RELEVANCE: Polygala tenuifolia is used in a variety of Chinese medicine prescriptions for the classic dementia t …
A review on the phytopharmacological studies of the genus Polygala.
Lacaille-Dubois MA, Delaude C, Mitaine-Offer AC. Lacaille-Dubois MA, et al. J Ethnopharmacol. 2020 Mar 1;249:112417. doi: 10.1016/j.jep.2019.112417. Epub 2019 Nov 22. J Ethnopharmacol. 2020. PMID: 31765761
ETHNOPHARMACOLOGICAL RELEVANCE: The genus Polygala, the most representative genus of the Polygalaceae family, comprises more than 600 species from all over the world of which around 40 are distributed in China, some of them, being used in the Traditional Chinese Medicine s …
ETHNOPHARMACOLOGICAL RELEVANCE: The genus Polygala, the most representative genus of the Polygalaceae family, comprises more than 600 …
[Research progress on Polygalae Radix].
Liu L, Feng WH, Liu XQ, Liang YH, Li C, Wang ZM. Liu L, et al. Zhongguo Zhong Yao Za Zhi. 2021 Nov;46(22):5744-5759. doi: 10.19540/j.cnki.cjcmm.20210518.601. Zhongguo Zhong Yao Za Zhi. 2021. PMID: 34951162 Review. Chinese.
Polygalae Radix has long been used in China for calming the mind, promoting intelligence, communicating the heart and kidney, eliminating phlegm, and reducing swelling. ...The present study reviews the research progress on chemical composition, pharmacological action, qual …
Polygalae Radix has long been used in China for calming the mind, promoting intelligence, communicating the heart and kidney, elimina …
3-Hy-droxy-1,2-dimeth-oxyxanthone.
Xiong HP, Wu ZJ, Chen FT, Chen DS. Xiong HP, et al. Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1667. doi: 10.1107/S160053681102160X. Epub 2011 Jun 18. Acta Crystallogr Sect E Struct Rep Online. 2011. PMID: 21837066 Free PMC article.
3-hy-droxy-1,2-dimeth-oxy-9H-xanthen-9-one), C(15)H(12)O(5), was isolated from Polygala arillata. The tricyclic unit is essentially planar (r.m.s. deviation = 0.039 A). ...
3-hy-droxy-1,2-dimeth-oxy-9H-xanthen-9-one), C(15)H(12)O(5), was isolated from Polygala arillata. The tricyclic unit is essentially p …
Active constituent of Polygala tenuifolia attenuates cognitive deficits by rescuing hippocampal neurogenesis in APP/PS1 transgenic mice.
Wang XF, Xiao HH, Wu YT, Kong L, Chen JC, Yang JX, Hu XL. Wang XF, et al. BMC Complement Med Ther. 2021 Oct 25;21(1):267. doi: 10.1186/s12906-021-03437-5. BMC Complement Med Ther. 2021. PMID: 34696749 Free PMC article.
BACKGROUND: Alzheimer's disease (AD) is the most common dementia worldwide, and there is still no satisfactory drug or therapeutic strategy. Polygala tenuifolia is a traditional Chinese medicine with multiple neuroprotective effects. In present study, we investigated the e …
BACKGROUND: Alzheimer's disease (AD) is the most common dementia worldwide, and there is still no satisfactory drug or therapeutic strategy. …
662 results