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An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective.
Wang KK, Nath R, Posner A, Raser KJ, Buroker-Kilgore M, Hajimohammadreza I, Probert A W Jr, Marcoux FW, Ye Q, Takano E, Hatanaka M, Maki M, Caner H, Collins JL, Fergus A, Lee KS, Lunney EA, Hays SJ, Yuen P. Wang KK, et al. Among authors: posner a. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6687-92. doi: 10.1073/pnas.93.13.6687. Proc Natl Acad Sci U S A. 1996. PMID: 8692879 Free PMC article.
Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis.
Nath R, Raser KJ, Stafford D, Hajimohammadreza I, Posner A, Allen H, Talanian RV, Yuen P, Gilbertsen RB, Wang KK. Nath R, et al. Among authors: posner a. Biochem J. 1996 Nov 1;319 ( Pt 3)(Pt 3):683-90. doi: 10.1042/bj3190683. Biochem J. 1996. PMID: 8920967 Free PMC article.
Alpha-mercaptoacrylic acid derivatives as novel selective calpain inhibitors.
Wang KK, Posner A, Raser KJ, Buroker-Kilgore M, Nath R, Hajimohammadreza I, Probert AW, Marcoux FW, Lunney EA, Hays SJ, Yuen P-W. Wang KK, et al. Among authors: posner a. Adv Exp Med Biol. 1996;389:95-101. doi: 10.1007/978-1-4613-0335-0_11. Adv Exp Med Biol. 1996. PMID: 8860998 Review. No abstract available.
MDM4 is a rational target for treating breast cancers with mutant p53.
Miranda PJ, Buckley D, Raghu D, Pang JB, Takano EA, Vijayakumaran R, Teunisse AF, Posner A, Procter T, Herold MJ, Gamell C, Marine JC, Fox SB, Jochemsen A, Haupt S, Haupt Y. Miranda PJ, et al. Among authors: posner a. J Pathol. 2017 Apr;241(5):661-670. doi: 10.1002/path.4877. Epub 2017 Mar 1. J Pathol. 2017. PMID: 28097652
CUP-AI-Dx: A tool for inferring cancer tissue of origin and molecular subtype using RNA gene-expression data and artificial intelligence.
Zhao Y, Pan Z, Namburi S, Pattison A, Posner A, Balachander S, Paisie CA, Reddi HV, Rueter J, Gill AJ, Fox S, Raghav KPS, Flynn WF, Tothill RW, Li S, Karuturi RKM, George J. Zhao Y, et al. Among authors: posner a. EBioMedicine. 2020 Nov;61:103030. doi: 10.1016/j.ebiom.2020.103030. Epub 2020 Oct 9. EBioMedicine. 2020. PMID: 33039710 Free PMC article.
γδ T Cells in Merkel Cell Carcinomas Have a Proinflammatory Profile Prognostic of Patient Survival.
Gherardin NA, Waldeck K, Caneborg A, Martelotto LG, Balachander S, Zethoven M, Petrone PM, Pattison A, Wilmott JS, Quiñones-Parra SM, Rossello F, Posner A, Wong A, Weppler AM, Shannon KF, Hong A, Ferguson PM, Jakrot V, Raleigh J, Hatzimihalis A, Neeson PJ, Deleso P, Johnston M, Chua M, Becker JC, Sandhu S, McArthur GA, Gill AJ, Scolyer RA, Hicks RJ, Godfrey DI, Tothill RW. Gherardin NA, et al. Among authors: posner a. Cancer Immunol Res. 2021 Jun;9(6):612-623. doi: 10.1158/2326-6066.CIR-20-0817. Epub 2021 Mar 5. Cancer Immunol Res. 2021. PMID: 33674358
376 results