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Page 1
Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection.
Haltalli MLR, Watcham S, Wilson NK, Eilers K, Lipien A, Ang H, Birch F, Anton SG, Pirillo C, Ruivo N, Vainieri ML, Pospori C, Sinden RE, Luis TC, Langhorne J, Duffy KR, Göttgens B, Blagborough AM, Lo Celso C. Haltalli MLR, et al. Among authors: pospori c. Nat Cell Biol. 2020 Dec;22(12):1399-1410. doi: 10.1038/s41556-020-00601-w. Epub 2020 Nov 23. Nat Cell Biol. 2020. PMID: 33230302 Free PMC article.
Metalloproteinase inhibition reduces AML growth, prevents stem cell loss, and improves chemotherapy effectiveness.
Pirillo C, Birch F, Tissot FS, Anton SG, Haltalli M, Tini V, Kong I, Piot C, Partridge B, Pospori C, Keeshan K, Santamaria S, Hawkins E, Falini B, Marra A, Duarte D, Lee CF, Roberts E, Lo Celso C. Pirillo C, et al. Among authors: pospori c. Blood Adv. 2022 May 24;6(10):3126-3141. doi: 10.1182/bloodadvances.2021004321. Blood Adv. 2022. PMID: 35157757 Free PMC article.
Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress.
Burt R, Dey A, Aref S, Aguiar M, Akarca A, Bailey K, Day W, Hooper S, Kirkwood A, Kirschner K, Lee SW, Lo Celso C, Manji J, Mansour MR, Marafioti T, Mitchell RJ, Muirhead RC, Cheuk Yan Ng K, Pospori C, Puccio I, Zuborne-Alapi K, Sahai E, Fielding AK. Burt R, et al. Among authors: pospori c. Blood. 2019 Oct 24;134(17):1415-1429. doi: 10.1182/blood.2019001398. Blood. 2019. PMID: 31501154 Free PMC article.
Redirection to the bone marrow improves T cell persistence and antitumor functions.
Khan AB, Carpenter B, Santos E Sousa P, Pospori C, Khorshed R, Griffin J, Velica P, Zech M, Ghorashian S, Forrest C, Thomas S, Gonzalez Anton S, Ahmadi M, Holler A, Flutter B, Ramirez-Ortiz Z, Means TK, Bennett CL, Stauss H, Morris E, Lo Celso C, Chakraverty R. Khan AB, et al. Among authors: pospori c. J Clin Invest. 2018 May 1;128(5):2010-2024. doi: 10.1172/JCI97454. Epub 2018 Apr 9. J Clin Invest. 2018. PMID: 29485974 Free PMC article.
Reversible CD8 T cell-neuron cross-talk causes aging-dependent neuronal regenerative decline.
Zhou L, Kong G, Palmisano I, Cencioni MT, Danzi M, De Virgiliis F, Chadwick JS, Crawford G, Yu Z, De Winter F, Lemmon V, Bixby J, Puttagunta R, Verhaagen J, Pospori C, Lo Celso C, Strid J, Botto M, Di Giovanni S. Zhou L, et al. Among authors: pospori c. Science. 2022 May 13;376(6594):eabd5926. doi: 10.1126/science.abd5926. Epub 2022 May 13. Science. 2022. PMID: 35549409
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