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Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses.
Urrutia A, Duffy D, Rouilly V, Posseme C, Djebali R, Illanes G, Libri V, Albaud B, Gentien D, Piasecka B, Hasan M, Fontes M, Quintana-Murci L, Albert ML; Milieu Intérieur Consortium. Urrutia A, et al. Among authors: posseme c. Cell Rep. 2016 Sep 6;16(10):2777-2791. doi: 10.1016/j.celrep.2016.08.011. Epub 2016 Aug 25. Cell Rep. 2016. PMID: 27568558 Free article.
Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges.
Piasecka B, Duffy D, Urrutia A, Quach H, Patin E, Posseme C, Bergstedt J, Charbit B, Rouilly V, MacPherson CR, Hasan M, Albaud B, Gentien D, Fellay J, Albert ML, Quintana-Murci L; Milieu Intérieur Consortium. Piasecka B, et al. Among authors: posseme c. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E488-E497. doi: 10.1073/pnas.1714765115. Epub 2017 Dec 27. Proc Natl Acad Sci U S A. 2018. PMID: 29282317 Free PMC article.
Variability of Primary Sjögren's Syndrome Is Driven by Interferon-α and Interferon-α Blood Levels Are Associated With the Class II HLA-DQ Locus.
Trutschel D, Bost P, Mariette X, Bondet V, Llibre A, Posseme C, Charbit B, Thorball CW, Jonsson R, Lessard CJ, Felten R, Ng WF, Chatenoud L, Dumortier H, Sibilia J, Fellay J, Brokstad KA, Appel S, Tarn JR, Quintana-Murci L, Mingueneau M, Meyer N, Duffy D, Schwikowski B, Gottenberg JE; Milieu Intérieur Consortium, ASSESS study investigators, and NECESSITY Consortium. Trutschel D, et al. Among authors: posseme c. Arthritis Rheumatol. 2022 Dec;74(12):1991-2002. doi: 10.1002/art.42265. Epub 2022 Nov 2. Arthritis Rheumatol. 2022. PMID: 35726083 Free PMC article.
Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation.
Posseme C, Llibre A, Charbit B, Bondet V, Rouilly V, Saint-André V, Boussier J, Bergstedt J, Smith N, Townsend L, Sugrue JA, Ní Cheallaigh C, Conlon N, Rotival M, Kobor MS, Mottez E, Pol S, Patin E, Albert ML, Quintana-Murci L, Duffy D; Milieu Intérieur Consortium. Posseme C, et al. Cell Rep. 2022 Jun 28;39(13):110989. doi: 10.1016/j.celrep.2022.110989. Cell Rep. 2022. PMID: 35767946 Free PMC article.
Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity.
Smith N, Possémé C, Bondet V, Sugrue J, Townsend L, Charbit B, Rouilly V, Saint-André V, Dott T, Pozo AR, Yatim N, Schwartz O, Cervantes-Gonzalez M, Ghosn J, Bastard P, Casanova JL, Szwebel TA, Terrier B, Conlon N, O'Farrelly C, Cheallaigh CN, Bourke NM, Duffy D. Smith N, et al. Among authors: posseme c. Nat Commun. 2022 Nov 25;13(1):7254. doi: 10.1038/s41467-022-34895-1. Nat Commun. 2022. PMID: 36434007 Free PMC article.
Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses.
Llibre A, Smith N, Rouilly V, Musvosvi M, Nemes E, Posseme C, Mabwe S, Charbit B, Mbandi SK, Filander E, Africa H, Saint-André V, Bondet V, Bost P, Mulenga H, Bilek N, Albert ML, Scriba TJ, Duffy D. Llibre A, et al. Among authors: posseme c. Front Immunol. 2022 Dec 14;13:897193. doi: 10.3389/fimmu.2022.897193. eCollection 2022. Front Immunol. 2022. PMID: 36591308 Free PMC article.
Differential levels of IFNα subtypes in autoimmunity and viral infection.
Bondet V, Rodero MP, Posseme C, Bost P, Decalf J, Haljasmägi L, Bekaddour N, Rice GI, Upasani V, Herbeuval JP, Reynolds JA, Briggs TA, Bruce IN, Mauri C, Isenberg D, Menon M, Hunt D, Schwikowski B, Mariette X, Pol S, Rozenberg F, Cantaert T, Eric Gottenberg J, Kisand K, Duffy D. Bondet V, et al. Among authors: posseme c. Cytokine. 2021 Aug;144:155533. doi: 10.1016/j.cyto.2021.155533. Epub 2021 Apr 30. Cytokine. 2021. PMID: 33941444 Free PMC article.
17 results