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High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes.
Charbord J, Poydenot P, Bonnefond C, Feyeux M, Casagrande F, Brinon B, Francelle L, Aurégan G, Guillermier M, Cailleret M, Viegas P, Nicoleau C, Martinat C, Brouillet E, Cattaneo E, Peschanski M, Lechuga M, Perrier AL. Charbord J, et al. Among authors: poydenot p. Stem Cells. 2013 Sep;31(9):1816-28. doi: 10.1002/stem.1430. Stem Cells. 2013. PMID: 23712629
Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.
Blondel S, Egesipe AL, Picardi P, Jaskowiak AL, Notarnicola M, Ragot J, Tournois J, Le Corf A, Brinon B, Poydenot P, Georges P, Navarro C, Pitrez PR, Ferreira L, Bollot G, Bauvais C, Laustriat D, Mejat A, De Sandre-Giovannoli A, Levy N, Bifulco M, Peschanski M, Nissan X. Blondel S, et al. Among authors: poydenot p. Cell Death Dis. 2016 Feb 18;7(2):e2105. doi: 10.1038/cddis.2015.374. Cell Death Dis. 2016. PMID: 26890144 Free PMC article.
Pluripotent Stem Cell-Based Drug Screening Reveals Cardiac Glycosides as Modulators of Myotonic Dystrophy Type 1.
Maury Y, Poydenot P, Brinon B, Lesueur L, Gide J, Roquevière S, Côme J, Polvèche H, Auboeuf D, Alexandre Denis J, Pietu G, Furling D, Lechuga M, Baghdoyan S, Peschanski M, Martinat C. Maury Y, et al. Among authors: poydenot p. iScience. 2019 Jan 25;11:258-271. doi: 10.1016/j.isci.2018.12.019. Epub 2018 Dec 27. iScience. 2019. PMID: 30639849 Free PMC article.
MBNL-dependent impaired development within the neuromuscular system in myotonic dystrophy type 1.
Tahraoui-Bories J, Mérien A, González-Barriga A, Lainé J, Leteur C, Polvèche H, Carteron A, De Lamotte JD, Nicoleau C, Polentes J, Jarrige M, Gomes-Pereira M, Ventre E, Poydenot P, Furling D, Schaeffer L, Legay C, Martinat C. Tahraoui-Bories J, et al. Among authors: poydenot p. Neuropathol Appl Neurobiol. 2023 Feb;49(1):e12876. doi: 10.1111/nan.12876. Neuropathol Appl Neurobiol. 2023. PMID: 36575942 Free PMC article.