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Higher topoisomerase 2 alpha gene transcript levels predict better prognosis in GBM patients receiving temozolomide chemotherapy: identification of temozolomide as a TOP2A inhibitor.
Arivazhagan A, Kumar DM, Sagar V, Patric IR, Sridevi S, Thota B, Srividya MR, Prasanna K, Thennarasu K, Mondal N, Hegde AS, Chandramouli BA, Santosh V, Rao MR, Kondaiah P, Somasundaram K. Arivazhagan A, et al. Among authors: prasanna k. J Neurooncol. 2012 Apr;107(2):289-97. doi: 10.1007/s11060-011-0758-3. Epub 2011 Nov 19. J Neurooncol. 2012. PMID: 22102081
Insulin growth factor-2 binding protein 3 (IGF2BP3) is a glioblastoma-specific marker that activates phosphatidylinositol 3-kinase/mitogen-activated protein kinase (PI3K/MAPK) pathways by modulating IGF-2.
Suvasini R, Shruti B, Thota B, Shinde SV, Friedmann-Morvinski D, Nawaz Z, Prasanna KV, Thennarasu K, Hegde AS, Arivazhagan A, Chandramouli BA, Santosh V, Somasundaram K. Suvasini R, et al. Among authors: prasanna kv. J Biol Chem. 2011 Jul 22;286(29):25882-90. doi: 10.1074/jbc.M110.178012. Epub 2011 May 25. J Biol Chem. 2011. PMID: 21613208 Free PMC article.
A fourteen gene GBM prognostic signature identifies association of immune response pathway and mesenchymal subtype with high risk group.
Arimappamagan A, Somasundaram K, Thennarasu K, Peddagangannagari S, Srinivasan H, Shailaja BC, Samuel C, Patric IR, Shukla S, Thota B, Prasanna KV, Pandey P, Balasubramaniam A, Santosh V, Chandramouli BA, Hegde AS, Kondaiah P, Sathyanarayana Rao MR. Arimappamagan A, et al. Among authors: prasanna kv. PLoS One. 2013 Apr 30;8(4):e62042. doi: 10.1371/journal.pone.0062042. Print 2013. PLoS One. 2013. PMID: 23646114 Free PMC article.
Grade-specific expression of insulin-like growth factor-binding proteins-2, -3, and -5 in astrocytomas: IGFBP-3 emerges as a strong predictor of survival in patients with newly diagnosed glioblastoma.
Santosh V, Arivazhagan A, Sreekanthreddy P, Srinivasan H, Thota B, Srividya MR, Vrinda M, Sridevi S, Shailaja BC, Samuel C, Prasanna KV, Thennarasu K, Balasubramaniam A, Chandramouli BA, Hegde AS, Somasundaram K, Kondaiah P, Rao MR. Santosh V, et al. Among authors: prasanna kv. Cancer Epidemiol Biomarkers Prev. 2010 Jun;19(6):1399-408. doi: 10.1158/1055-9965.EPI-09-1213. Epub 2010 May 25. Cancer Epidemiol Biomarkers Prev. 2010. PMID: 20501753
65 results